Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001120690                                                           18    1482
NP_006221                                                              18    1482
NP_001243808                                                           18    1482
XP_006715808                                                           18    1482
NP_000811                                                              16    5631
NP_775792                                                              16    7355
NP_001074020                                                           16    7355
XP_006717039                                                           16    7355
XP_006717038                                                           16    7355
XP_005251795                                                           16    7355
XP_006717037                                                           16    7355
NP_115763                                                              15    9605
NP_689549                                                              15    9605
NP_002970                                                              15    9605
NP_005161                                                              15    9605
NP_001273700                                                           15    9605
NP_444514                                                              15    9605
NP_115593                                                              15    9605
NP_942592                                                              15    9605
NP_001007099                                                           15    9605
NP_001180529                                                           15    9605
XP_006725043                                                           15    9605
XP_006725041                                                           15    9605
XP_006725040                                                           15    9605
XP_006725039                                                           15    9605
XP_006725038                                                           15    9605
XP_006725037                                                           15    9605
XP_006722085                                                           15    9605
XP_006722084                                                           15    9605
XP_005257655                                                           15    9605
XP_006722083                                                           15    9605
XP_005257654                                                           15    9605
XP_005257653                                                           15    9605
XP_005257652                                                           15    9605
XP_005265728                                                           15    9605
XP_005265724                                                           15    9605
XP_006712378                                                           15    9605
XP_005263945                                                           15    9605
XP_006712376                                                           15    9605
XP_006712375                                                           15    9605
XP_006712374                                                           15    9605
XP_006712371                                                           15    9605
XP_006711911                                                           15    9605
XP_006711910                                                           15    9605
XP_006711909                                                           15    9605
XP_006711908                                                           15    9605
XP_006711907                                                           15    9605
XP_006711906                                                           15    9605
XP_005271161                                                           15    9605
XP_005271160                                                           15    9605
NP_001366                                                              15    9605
>NP_001120690
          Length = 469

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YSATQSAC 9
           +SATQ+AC
Sbjct: 431 FSATQTAC 438
>NP_006221
          Length = 504

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YSATQSAC 9
           +SATQ+AC
Sbjct: 466 FSATQTAC 473
>NP_001243808
          Length = 469

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YSATQSAC 9
           +SATQ+AC
Sbjct: 431 FSATQTAC 438
>XP_006715808
          Length = 488

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YSATQSAC 9
           +SATQ+AC
Sbjct: 450 FSATQTAC 457
>NP_000811
          Length = 678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           AYS+ + AC
Sbjct: 228 AYSSQEKAC 236
>NP_775792
          Length = 1444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    YSATQSAC 9
            Y A Q+AC
Sbjct: 1312 YGAQQTAC 1319
>NP_001074020
          Length = 1405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    YSATQSAC 9
            Y A Q+AC
Sbjct: 1273 YGAQQTAC 1280
>XP_006717039
          Length = 1370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    YSATQSAC 9
            Y A Q+AC
Sbjct: 1238 YGAQQTAC 1245
>XP_006717038
          Length = 1473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    YSATQSAC 9
            Y A Q+AC
Sbjct: 1341 YGAQQTAC 1348
>XP_005251795
          Length = 1508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    YSATQSAC 9
            Y A Q+AC
Sbjct: 1376 YGAQQTAC 1383
>XP_006717037
          Length = 1508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    YSATQSAC 9
            Y A Q+AC
Sbjct: 1376 YGAQQTAC 1383
>NP_115763
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 575 SYSSTTSDC 583
>NP_689549
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YSATQSAC 9
           YS  QS+C
Sbjct: 350 YSKDQSSC 357
>NP_002970
          Length = 547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  YSATQSAC 9
          YSA   AC
Sbjct: 54 YSAVDQAC 61
>NP_005161
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   AYSATQSAC 9
           AYS+  S C
Sbjct: 164 AYSSDDSGC 172
>NP_001273700
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ATQSAC 9
            +TQSAC
Sbjct: 2112 STQSAC 2117
>NP_444514
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2   YSATQSAC 9
           Y A Q AC
Sbjct: 344 YEACQQAC 351
>NP_115593
          Length = 2603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ATQSAC 9
            +TQSAC
Sbjct: 2225 STQSAC 2230
>NP_942592
          Length = 2352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ATQSAC 9
            +TQSAC
Sbjct: 1974 STQSAC 1979
>NP_001007099
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  YSATQSAC 9
          YSA   AC
Sbjct: 54 YSAVDQAC 61
>NP_001180529
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  YSATQSAC 9
          YSA   AC
Sbjct: 54 YSAVDQAC 61
>XP_006725043
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725041
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725040
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725039
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725038
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725037
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006722085
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 239 SYSSTTSDC 247
>XP_006722084
          Length = 943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 239 SYSSTTSDC 247
>XP_005257655
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 267 SYSSTTSDC 275
>XP_006722083
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 575 SYSSTTSDC 583
>XP_005257654
          Length = 1237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 575 SYSSTTSDC 583
>XP_005257653
          Length = 1242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 575 SYSSTTSDC 583
>XP_005257652
          Length = 1279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AYSATQSAC 9
           +YS+T S C
Sbjct: 575 SYSSTTSDC 583
>XP_005265728
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ATQSAC 9
            +TQSAC
Sbjct: 1973 STQSAC 1978
>XP_005265724
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    ATQSAC 9
            +TQSAC
Sbjct: 2224 STQSAC 2229
>XP_006712378
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ATQSAC 9
           ATQS+C
Sbjct: 635 ATQSSC 640
>XP_005263945
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ATQSAC 9
           ATQS+C
Sbjct: 635 ATQSSC 640
>XP_006712376
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ATQSAC 9
           ATQS+C
Sbjct: 641 ATQSSC 646
>XP_006712375
          Length = 685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ATQSAC 9
           ATQS+C
Sbjct: 641 ATQSSC 646
>XP_006712374
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ATQSAC 9
           ATQS+C
Sbjct: 685 ATQSSC 690
>XP_006712371
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ATQSAC 9
           ATQS+C
Sbjct: 685 ATQSSC 690
>XP_006711911
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711910
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711909
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711908
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711907
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711906
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AYSATQSA 8
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_005271161
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  YSATQSAC 9
          YSA   AC
Sbjct: 54 YSAVDQAC 61
>XP_005271160
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  YSATQSAC 9
          YSA   AC
Sbjct: 54 YSAVDQAC 61
>NP_001366
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   AYSATQSAC 9
           AYS   SAC
Sbjct: 143 AYSWPHSAC 151
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.102    0.296 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 396,761
Number of extensions: 773
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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