Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              21     229
NP_001153182                                                           18    1935
NP_001153179                                                           18    1935
NP_001035552                                                           18    1935
NP_001153181                                                           18    1935
NP_037472                                                              17    2528
NP_078948                                                              17    3301
XP_005263278                                                           17    3301
XP_005263277                                                           17    3301
NP_006217                                                              16    5631
XP_005246701                                                           16    5631
XP_005246700                                                           16    5631
NP_780778                                                              16    7355
NP_001092805                                                           16    7355
NP_055574                                                              16    7355
NP_005896                                                              16    7355
NP_001120689                                                           16    7355
NP_001135392                                                           16    7355
NP_001135391                                                           16    7355
XP_005274644                                                           16    7355
XP_005266461                                                           16    7355
XP_005266460                                                           16    7355
XP_005266458                                                           16    7355
XP_006719890                                                           16    7355
XP_006716479                                                           16    7355
NP_997244                                                              15    9605
NP_005492                                                              15    9605
NP_079350                                                              15    9605
NP_002195                                                              15    9605
NP_061325                                                              15    9605
NP_940998                                                              15    9605
NP_001155313                                                           15    9605
NP_689835                                                              15    9605
NP_000188                                                              15    9605
NP_775922                                                              15    9605
XP_005276759                                                           15    9605
XP_005276750                                                           15    9605
XP_003846353                                                           15    9605
XP_005261913                                                           15    9605
XP_005261910                                                           15    9605
XP_005261905                                                           15    9605
XP_003846349                                                           15    9605
XP_006723893                                                           15    9605
XP_005260515                                                           15    9605
XP_006723892                                                           15    9605
XP_006723891                                                           15    9605
XP_006723890                                                           15    9605
XP_005257365                                                           15    9605
XP_005252027                                                           15    9605
XP_006717157                                                           15    9605
XP_005248505                                                           15    9605
XP_006714380                                                           15    9605
XP_006714379                                                           15    9605
XP_006714378                                                           15    9605
XP_006714377                                                           15    9605
XP_005264092                                                           15    9605
XP_003960959                                                           15    9605
NP_004852                                                              15    9605
>NP_004351
          Length = 882

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  AYFSLNTRF 9
          AYFSL+TRF
Sbjct: 67 AYFSLDTRF 75
>NP_001153182
          Length = 316

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YFSLNTRF 9
           YF+LN RF
Sbjct: 204 YFTLNPRF 211
>NP_001153179
          Length = 384

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YFSLNTRF 9
           YF+LN RF
Sbjct: 272 YFTLNPRF 279
>NP_001035552
          Length = 500

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YFSLNTRF 9
           YF+LN RF
Sbjct: 388 YFTLNPRF 395
>NP_001153181
          Length = 375

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YFSLNTRF 9
           YF+LN RF
Sbjct: 263 YFTLNPRF 270
>NP_037472
          Length = 818

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YFSLNTRF 9
           YF L+TRF
Sbjct: 177 YFHLHTRF 184
>NP_078948
          Length = 903

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AYFSLNTRF 9
           AY++L TR+
Sbjct: 637 AYYNLETRY 645
>XP_005263278
          Length = 620

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AYFSLNTRF 9
           AY++L TR+
Sbjct: 354 AYYNLETRY 362
>XP_005263277
          Length = 759

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AYFSLNTRF 9
           AY++L TR+
Sbjct: 493 AYYNLETRY 501
>NP_006217
          Length = 1095

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS NT+
Sbjct: 705 SYFSANTK 712
>XP_005246701
          Length = 1016

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS NT+
Sbjct: 626 SYFSANTK 633
>XP_005246700
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS NT+
Sbjct: 631 SYFSANTK 638
>NP_780778
          Length = 180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           +YF LN R
Sbjct: 161 SYFKLNNR 168
>NP_001092805
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YFSLNTRF 9
           +FS NT F
Sbjct: 183 FFSCNTEF 190
>NP_055574
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YFSLNTRF 9
           +FS NT F
Sbjct: 183 FFSCNTEF 190
>NP_005896
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY+ LN R
Sbjct: 240 AYYELNNR 247
>NP_001120689
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY+ LN R
Sbjct: 277 AYYELNNR 284
>NP_001135392
          Length = 181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           +YF LN R
Sbjct: 162 SYFKLNNR 169
>NP_001135391
          Length = 195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           +YF LN R
Sbjct: 176 SYFKLNNR 183
>XP_005274644
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           +YF LN R
Sbjct: 177 SYFKLNNR 184
>XP_005266461
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY+ LN R
Sbjct: 154 AYYELNNR 161
>XP_005266460
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY+ LN R
Sbjct: 191 AYYELNNR 198
>XP_005266458
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY+ LN R
Sbjct: 240 AYYELNNR 247
>XP_006719890
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY+ LN R
Sbjct: 277 AYYELNNR 284
>XP_006716479
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YFSLNTRF 9
           +FS NT F
Sbjct: 183 FFSCNTEF 190
>NP_997244
          Length = 3169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AYFSLNTR 8
            A FSLNT+
Sbjct: 2855 AEFSLNTQ 2862
>NP_005492
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FSLNTRF 9
          F+L+TRF
Sbjct: 33 FNLDTRF 39
>NP_079350
          Length = 4012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FSLNTRF 9
            +SLNT F
Sbjct: 3660 YSLNTEF 3666
>NP_002195
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FSLNTRF 9
          F+L+TRF
Sbjct: 33 FNLDTRF 39
>NP_061325
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 781 YFDLNT 786
>NP_940998
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 781 YFDLNT 786
>NP_001155313
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 781 YFDLNT 786
>NP_689835
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YFSLNTRF 9
           YF+  TRF
Sbjct: 331 YFAQQTRF 338
>NP_000188
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY  LNT+
Sbjct: 301 AYLKLNTK 308
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    AYFSLNT 7
            A+FS NT
Sbjct: 4450 AFFSFNT 4456
>XP_005276759
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS+N +
Sbjct: 129 SYFSINAK 136
>XP_005276750
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS+N +
Sbjct: 129 SYFSINAK 136
>XP_003846353
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS+N +
Sbjct: 129 SYFSINAK 136
>XP_005261913
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   YFSLNTR 8
           YF LN R
Sbjct: 275 YFKLNAR 281
>XP_005261910
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   YFSLNTR 8
           YF LN R
Sbjct: 275 YFKLNAR 281
>XP_005261905
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   YFSLNTR 8
           YF LN R
Sbjct: 275 YFKLNAR 281
>XP_003846349
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS+N +
Sbjct: 129 SYFSINAK 136
>XP_006723893
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 781 YFDLNT 786
>XP_005260515
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 781 YFDLNT 786
>XP_006723892
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 782 YFDLNT 787
>XP_006723891
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 782 YFDLNT 787
>XP_006723890
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   YFSLNT 7
           YF LNT
Sbjct: 782 YFDLNT 787
>XP_005257365
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FSLNTRF 9
          F+L+TRF
Sbjct: 33 FNLDTRF 39
>XP_005252027
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY  LNT+
Sbjct: 181 AYLKLNTK 188
>XP_006717157
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   AYFSLNTR 8
           AY  LNT+
Sbjct: 247 AYLKLNTK 254
>XP_005248505
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YFSLNTRF 9
           YF+  TRF
Sbjct: 332 YFAQQTRF 339
>XP_006714380
          Length = 3897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FSLNTRF 9
            +SLNT F
Sbjct: 3545 YSLNTEF 3551
>XP_006714379
          Length = 3936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FSLNTRF 9
            +SLNT F
Sbjct: 3584 YSLNTEF 3590
>XP_006714378
          Length = 3965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FSLNTRF 9
            +SLNT F
Sbjct: 3613 YSLNTEF 3619
>XP_006714377
          Length = 4010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FSLNTRF 9
            +SLNT F
Sbjct: 3658 YSLNTEF 3664
>XP_005264092
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AYFSLNTR 8
          +YF L+TR
Sbjct: 8  SYFPLSTR 15
>XP_003960959
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AYFSLNTR 8
           +YFS+N +
Sbjct: 129 SYFSINAK 136
>NP_004852
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   YFSLNTR 8
           YF LN R
Sbjct: 275 YFKLNAR 281
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.141    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 421,915
Number of extensions: 613
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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