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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005270509                                                           17    4312
XP_005270508                                                           17    4312
NP_055140                                                              16    5631
NP_001098707                                                           16    5631
NP_001263400                                                           16    5631
NP_056170                                                              16    5631
NP_620636                                                              16    5631
NP_005724                                                              16    5631
NP_003062                                                              16    5631
XP_006721857                                                           16    5631
XP_005258011                                                           16    5631
XP_006714577                                                           16    5631
XP_005247781                                                           16    5631
NP_002462                                                              16    7355
NP_112176                                                              16    7355
NP_001252511                                                           16    7355
NP_001129419                                                           16    7355
XP_006720215                                                           16    7355
XP_006720214                                                           16    7355
XP_005267751                                                           16    7355
NP_001073932                                                           15    9605
NP_001368                                                              15    9605
XP_006718966                                                           15    9605
XP_006711533                                                           15    9605
XP_005245422                                                           15    9605
NP_065821                                                              15    9605

>XP_005270509
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVKKNLL 8
           +VKKNLL
Sbjct: 341 IVKKNLL 347



>XP_005270508
          Length = 430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVKKNLL 8
           +VKKNLL
Sbjct: 422 IVKKNLL 428



>NP_055140
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVKKNLL 8
           VVKKN+L
Sbjct: 404 VVKKNIL 410



>NP_001098707
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVKKNLL 8
           VVKKN+L
Sbjct: 457 VVKKNIL 463



>NP_001263400
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VVKKNLL 8
           VVKKN+L
Sbjct: 404 VVKKNIL 410



>NP_056170
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VVKKNLLR 9
           ++KKNL R
Sbjct: 647 IIKKNLCR 654



>NP_620636
          Length = 1009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKKNLLR 9
           VKKNLL+
Sbjct: 323 VKKNLLK 329



>NP_005724
          Length = 890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  AVVKKNLL 8
          +VV+KNLL
Sbjct: 33 SVVRKNLL 40



>NP_003062
          Length = 1009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKKNLLR 9
           VKKNLL+
Sbjct: 323 VKKNLLK 329



>XP_006721857
          Length = 603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VVKKNLLR 9
           ++KKNL R
Sbjct: 511 IIKKNLCR 518



>XP_005258011
          Length = 716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VVKKNLLR 9
           ++KKNL R
Sbjct: 624 IIKKNLCR 631



>XP_006714577
          Length = 890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  AVVKKNLL 8
          +VV+KNLL
Sbjct: 33 SVVRKNLL 40



>XP_005247781
          Length = 1008

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKKNLLR 9
           VKKNLL+
Sbjct: 323 VKKNLLK 329



>NP_002462
          Length = 1939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KKNLLR 9
            KKNLLR
Sbjct: 1860 KKNLLR 1865



>NP_112176
          Length = 101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VKKNLLR 9
          +KKNLL+
Sbjct: 45 IKKNLLK 51



>NP_001252511
          Length = 63

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VKKNLLR 9
          +KKNLL+
Sbjct: 45 IKKNLLK 51



>NP_001129419
          Length = 146

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VKKNLLR 9
          +KKNLL+
Sbjct: 45 IKKNLLK 51



>XP_006720215
          Length = 1968

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KKNLLR 9
            KKNLLR
Sbjct: 1889 KKNLLR 1894



>XP_006720214
          Length = 1978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KKNLLR 9
            KKNLLR
Sbjct: 1899 KKNLLR 1904



>XP_005267751
          Length = 1979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    KKNLLR 9
            KKNLLR
Sbjct: 1900 KKNLLR 1905



>NP_001073932
          Length = 4314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VKKNLLR 9
            +KKNL+R
Sbjct: 3843 LKKNLMR 3849



>NP_001368
          Length = 4307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VKKNLLR 9
            +KKNL+R
Sbjct: 3836 LKKNLMR 3842



>XP_006718966
          Length = 4300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VKKNLLR 9
            +KKNL+R
Sbjct: 3829 LKKNLMR 3835



>XP_006711533
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVKKNLLR 9
           V+KK LLR
Sbjct: 629 VLKKELLR 636



>XP_005245422
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVKKNLLR 9
           V+KK LLR
Sbjct: 629 VLKKELLR 636



>NP_065821
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVKKNLLR 9
           V+KK LLR
Sbjct: 629 VLKKELLR 636



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.137    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 419,214
Number of extensions: 513
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)