Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_001157717                                                           17    3301
NP_001157718                                                           17    3301
NP_060317                                                              17    3301
XP_006711463                                                           17    3301
XP_006711462                                                           17    3301
NP_631899                                                              16    5631
NP_001070710                                                           16    5631
NP_899630                                                              16    7355
NP_068591                                                              16    7355
XP_006713441                                                           16    7355
XP_006713435                                                           16    7355
XP_006713432                                                           16    7355
NP_663306                                                              15    9605
NP_003179                                                              15    9605
NP_663304                                                              15    9605
NP_663305                                                              15    9605
NP_000180                                                              15    9605
NP_000179                                                              15    9605
NP_277033                                                              15    9605
NP_277032                                                              15    9605
NP_277035                                                              15    9605
NP_277031                                                              15    9605
NP_002106                                                              15    9605
NP_001438                                                              15    9605
NP_079406                                                              15    9605
NP_001240723                                                           15    9605
NP_001240719                                                           15    9605
NP_001240720                                                           15    9605
NP_001240722                                                           15    9605
XP_005255387                                                           15    9605
XP_005269794                                                           15    9605
XP_005269793                                                           15    9605
XP_005269792                                                           15    9605
XP_006714824                                                           15    9605
XP_005264337                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVVEETIGR 9
            A VEETIGR
Sbjct: 1743 AAVEETIGR 1751
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVVEETIGR 9
            A VEETIGR
Sbjct: 1743 AAVEETIGR 1751
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVVEETIGR 9
            A VEETIGR
Sbjct: 1696 AAVEETIGR 1704
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVVEETIGR 9
            A VEETIGR
Sbjct: 1775 AAVEETIGR 1783
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVVEETIGR 9
            A VEETIGR
Sbjct: 1775 AAVEETIGR 1783
>NP_001157717
          Length = 431

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VVEETIGR 9
          +VEET+G+
Sbjct: 6  IVEETVGQ 13
>NP_001157718
          Length = 422

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VVEETIGR 9
          +VEET+G+
Sbjct: 6  IVEETVGQ 13
>NP_060317
          Length = 454

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VVEETIGR 9
          +VEET+G+
Sbjct: 6  IVEETVGQ 13
>XP_006711463
          Length = 374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VVEETIGR 9
          +VEET+G+
Sbjct: 6  IVEETVGQ 13
>XP_006711462
          Length = 406

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VVEETIGR 9
          +VEET+G+
Sbjct: 6  IVEETVGQ 13
>NP_631899
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EETIGR 9
           EETIGR
Sbjct: 196 EETIGR 201
>NP_001070710
          Length = 511

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EETIGR 9
           EETIGR
Sbjct: 205 EETIGR 210
>NP_899630
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AVVEETIGR 9
           A +EE +GR
Sbjct: 840 AKIEENVGR 848
>NP_068591
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VEETIGR 9
           +EET+GR
Sbjct: 309 LEETLGR 315
>XP_006713441
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AVVEETIGR 9
           A +EE +GR
Sbjct: 691 AKIEENVGR 699
>XP_006713435
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AVVEETIGR 9
           A +EE +GR
Sbjct: 691 AKIEENVGR 699
>XP_006713432
          Length = 1184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AVVEETIGR 9
           A +EE +GR
Sbjct: 691 AKIEENVGR 699
>NP_663306
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VEETIGR 9
          VEE +GR
Sbjct: 38 VEEVVGR 44
>NP_003179
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VEETIGR 9
          VEE +GR
Sbjct: 38 VEEVVGR 44
>NP_663304
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VEETIGR 9
          VEE +GR
Sbjct: 38 VEEVVGR 44
>NP_663305
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VEETIGR 9
          VEE +GR
Sbjct: 38 VEEVVGR 44
>NP_000180
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 205 AVVNDTVG 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 653 AVVNDTVG 660
>NP_000179
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 205 AVVNDTVG 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 653 AVVNDTVG 660
>NP_277033
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 209 AVVNDTVG 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 657 AVVNDTVG 664
>NP_277032
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 209 AVVNDTVG 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 657 AVVNDTVG 664
>NP_277035
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 193 AVVNDTVG 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 641 AVVNDTVG 648
>NP_277031
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 204 AVVNDTVG 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 652 AVVNDTVG 659
>NP_002106
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 218 AVVNDTVG 225
>NP_001438
          Length = 4349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EETIGR 9
            EET+GR
Sbjct: 3571 EETLGR 3576
>NP_079406
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 652 AVVNDTVG 659
>NP_001240723
          Length = 88

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AVVEETIGR 9
          A V+E +GR
Sbjct: 10 ATVQEVLGR 18
>NP_001240719
          Length = 83

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AVVEETIGR 9
          A V+E +GR
Sbjct: 10 ATVQEVLGR 18
>NP_001240720
          Length = 88

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AVVEETIGR 9
          A V+E +GR
Sbjct: 10 ATVQEVLGR 18
>NP_001240722
          Length = 83

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AVVEETIGR 9
          A V+E +GR
Sbjct: 10 ATVQEVLGR 18
>XP_005255387
          Length = 88

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AVVEETIGR 9
          A V+E +GR
Sbjct: 10 ATVQEVLGR 18
>XP_005269794
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 177 AVVNDTVG 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 625 AVVNDTVG 632
>XP_005269793
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 209 AVVNDTVG 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 657 AVVNDTVG 664
>XP_005269792
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 248 AVVNDTVG 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 696 AVVNDTVG 703
>XP_006714824
          Length = 4349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    EETIGR 9
            EET+GR
Sbjct: 3571 EETLGR 3576
>XP_005264337
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 205 AVVNDTVG 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVVEETIG 8
           AVV +T+G
Sbjct: 674 AVVNDTVG 681
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.132    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,819
Number of extensions: 557
Number of successful extensions: 50
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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