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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1482
NP_001138390                                                           18    1482
NP_001138386                                                           18    1482
NP_001138387                                                           18    1482
NP_000132                                                              18    1482
NP_075259                                                              18    1482
NP_001138388                                                           18    1482
NP_001138391                                                           18    1482
NP_001138385                                                           18    1482
NP_075418                                                              18    1482
XP_006717776                                                           18    1482
XP_006717775                                                           18    1482
XP_006717774                                                           18    1482
XP_006717773                                                           18    1482
XP_006717772                                                           18    1482
XP_006717771                                                           18    1482
NP_001156685                                                           17    4312
NP_000133                                                              17    4312
NP_075254                                                              17    4312
XP_006713936                                                           17    4312
XP_006713935                                                           17    4312
XP_006713934                                                           17    4312
XP_006713933                                                           17    4312
XP_006713932                                                           17    4312
XP_006713931                                                           17    4312
NP_061146                                                              16    7355
NP_954872                                                              16    7355
NP_001027466                                                           15    9605
NP_000053                                                              15    9605

>NP_001138389
          Length = 705

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 395 AVTVAVKML 403



>NP_001138390
          Length = 704

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 394 AVTVAVKML 402



>NP_001138386
          Length = 709

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 399 AVTVAVKML 407



>NP_001138387
          Length = 707

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 422 AVTVAVKML 430



>NP_000132
          Length = 821

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 511 AVTVAVKML 519



>NP_075259
          Length = 822

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 512 AVTVAVKML 520



>NP_001138388
          Length = 706

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 396 AVTVAVKML 404



>NP_001138391
          Length = 680

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 423 AVTVAVKML 431



>NP_001138385
          Length = 769

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 512 AVTVAVKML 520



>NP_075418
          Length = 732

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 422 AVTVAVKML 430



>XP_006717776
          Length = 806

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 530 AVTVAVKML 538



>XP_006717775
          Length = 726

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 416 AVTVAVKML 424



>XP_006717774
          Length = 752

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 442 AVTVAVKML 450



>XP_006717773
          Length = 807

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 531 AVTVAVKML 539



>XP_006717772
          Length = 838

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 528 AVTVAVKML 536



>XP_006717771
          Length = 839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AVTVVVKML 9
           AVTV VKML
Sbjct: 529 AVTVAVKML 537



>NP_001156685
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 505 VTVAVKML 512



>NP_000133
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 503 VTVAVKML 510



>NP_075254
          Length = 694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 391 VTVAVKML 398



>XP_006713936
          Length = 807

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 503 VTVAVKML 510



>XP_006713935
          Length = 807

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 504 VTVAVKML 511



>XP_006713934
          Length = 809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 505 VTVAVKML 512



>XP_006713933
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 506 VTVAVKML 513



>XP_006713932
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 507 VTVAVKML 514



>XP_006713931
          Length = 811

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VTVVVKML 9
           VTV VKML
Sbjct: 507 VTVAVKML 514



>NP_061146
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTVVVKML 9
           VTVV+K+L
Sbjct: 215 VTVVLKLL 222



>NP_954872
          Length = 799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTVVVKML 9
           VTVV+K+L
Sbjct: 215 VTVVLKLL 222



>NP_001027466
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AVTVVVKML 9
          A TV+ KML
Sbjct: 46 ATTVISKML 54



>NP_000053
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AVTVVVKML 9
          A TV+ KML
Sbjct: 46 ATTVISKML 54



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.136    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 219,298
Number of extensions: 157
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)