Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           19     869
NP_000170                                                              19     869
NP_001268422                                                           19     869
NP_001268423                                                           19     869
XP_005264328                                                           19     869
NP_113642                                                              16    7355
NP_003645                                                              15    9605
NP_001157973                                                           15    9605
NP_062817                                                              15    9605
NP_065961                                                              15    9605
NP_001158137                                                           15    9605
XP_005261745                                                           15    9605
XP_005261744                                                           15    9605
XP_005261743                                                           15    9605
XP_006724347                                                           15    9605
XP_006724346                                                           15    9605
XP_006724345                                                           15    9605
XP_006724344                                                           15    9605
XP_006718420                                                           15    9605
XP_006718419                                                           15    9605
XP_006716134                                                           15    9605
NP_001245312                                                           15    9605
>NP_001268421
          Length = 1230

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSTTRSGA 9
           VSTTRSGA
Sbjct: 587 VSTTRSGA 594
>NP_000170
          Length = 1360

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSTTRSGA 9
           VSTTRSGA
Sbjct: 717 VSTTRSGA 724
>NP_001268422
          Length = 1058

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSTTRSGA 9
           VSTTRSGA
Sbjct: 415 VSTTRSGA 422
>NP_001268423
          Length = 1058

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSTTRSGA 9
           VSTTRSGA
Sbjct: 415 VSTTRSGA 422
>XP_005264328
          Length = 1261

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSTTRSGA 9
           VSTTRSGA
Sbjct: 618 VSTTRSGA 625
>NP_113642
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VSTTRSGA 9
           V TTR+GA
Sbjct: 211 VPTTRAGA 218
>NP_003645
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VSTTRSGA 9
          ++TTRSG+
Sbjct: 66 LATTRSGS 73
>NP_001157973
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 130 AVSSRRSGS 138
>NP_062817
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 130 AVSSRRSGS 138
>NP_065961
          Length = 1934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VSTTRSGA 9
           VSTT +GA
Sbjct: 883 VSTTSTGA 890
>NP_001158137
          Length = 1950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VSTTRSGA 9
           VSTT +GA
Sbjct: 883 VSTTSTGA 890
>XP_005261745
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 130 AVSSRRSGS 138
>XP_005261744
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 130 AVSSRRSGS 138
>XP_005261743
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 130 AVSSRRSGS 138
>XP_006724347
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 171 AVSSRRSGS 179
>XP_006724346
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 171 AVSSRRSGS 179
>XP_006724345
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 171 AVSSRRSGS 179
>XP_006724344
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSTTRSGA 9
           AVS+ RSG+
Sbjct: 171 AVSSRRSGS 179
>XP_006718420
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VSTTRSGA 9
          ++TTRSG+
Sbjct: 66 LATTRSGS 73
>XP_006718419
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VSTTRSGA 9
          ++TTRSG+
Sbjct: 66 LATTRSGS 73
>XP_006716134
          Length = 1847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VSTTRSGA 9
           VSTT +GA
Sbjct: 780 VSTTSTGA 787
>NP_001245312
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  VSTTRSG 8
          VST RSG
Sbjct: 10 VSTARSG 16
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.102    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 356,066
Number of extensions: 508
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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