Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000262                                                              17    2528
XP_006722542                                                           17    2528
XP_005258336                                                           17    2528
XP_005258335                                                           17    2528
XP_005258334                                                           17    2528
NP_037521                                                              16    5631
NP_001095118                                                           16    5631
NP_443137                                                              16    7355
NP_783863                                                              16    7355
NP_944489                                                              16    7355
XP_005269276                                                           16    7355
XP_006719749                                                           16    7355
XP_005269275                                                           16    7355
XP_005246323                                                           16    7355
XP_005246322                                                           16    7355
XP_006712291                                                           16    7355
XP_005246320                                                           16    7355
NP_000278                                                              15    9605
NP_057228                                                              15    9605
NP_852006                                                              15    9605
NP_055640                                                              15    9605
NP_065961                                                              15    9605
NP_001158137                                                           15    9605
NP_005823                                                              15    9605
NP_001265840                                                           15    9605
XP_006716134                                                           15    9605
XP_005249237                                                           15    9605
>NP_000262
          Length = 1278

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            AVSLVN+++
Sbjct: 1151 AVSLVNLVM 1159
>XP_006722542
          Length = 1273

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            AVSLVN+++
Sbjct: 1168 AVSLVNLVM 1176
>XP_005258336
          Length = 1286

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            AVSLVN+++
Sbjct: 1151 AVSLVNLVM 1159
>XP_005258335
          Length = 1295

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            AVSLVN+++
Sbjct: 1168 AVSLVNLVM 1176
>XP_005258334
          Length = 1303

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            AVSLVN+++
Sbjct: 1168 AVSLVNLVM 1176
>NP_037521
          Length = 1359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AVSLVNII 8
            AVSL+N++
Sbjct: 1192 AVSLINLV 1199
>NP_001095118
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AVSLVNII 8
            AVSL+N++
Sbjct: 1165 AVSLINLV 1172
>NP_443137
          Length = 1092

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 893 AVSLENVLL 901
>NP_783863
          Length = 1027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 838 AVSLENVLL 846
>NP_944489
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 787 AVSLENVLL 795
>XP_005269276
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 735 AVSLENVLL 743
>XP_006719749
          Length = 977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 787 AVSLENVLL 795
>XP_005269275
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 838 AVSLENVLL 846
>XP_005246323
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 870 AVSLENVLL 878
>XP_005246322
          Length = 1084

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 893 AVSLENVLL 901
>XP_006712291
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 893 AVSLENVLL 901
>XP_005246320
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AVSLVNIIL 9
           AVSL N++L
Sbjct: 893 AVSLENVLL 901
>NP_000278
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AVSLVNII 8
           +VSLVN++
Sbjct: 895 SVSLVNVL 902
>NP_057228
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AVSLVNII 8
          AVSL+N I
Sbjct: 18 AVSLINAI 25
>NP_852006
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AVSLVNIIL 9
           ++SLVN+++
Sbjct: 155 SMSLVNVVM 163
>NP_055640
          Length = 2271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AVSLVNIIL 9
           A+SL+++IL
Sbjct: 455 ALSLISVIL 463
>NP_065961
          Length = 1934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            A+S++N+++
Sbjct: 1010 AISVINVLI 1018
>NP_001158137
          Length = 1950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1    AVSLVNIIL 9
            A+S++N+++
Sbjct: 1010 AISVINVLI 1018
>NP_005823
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AVSLVNIIL 9
           ++SLVN+++
Sbjct: 155 SMSLVNVVM 163
>NP_001265840
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AVSLVNIIL 9
           ++SLVN+++
Sbjct: 155 SMSLVNVVM 163
>XP_006716134
          Length = 1847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1   AVSLVNIIL 9
           A+S++N+++
Sbjct: 907 AISVINVLI 915
>XP_005249237
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AVSLVNII 8
           +VSLVN++
Sbjct: 807 SVSLVNVL 814
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.147    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 295,448
Number of extensions: 411
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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