Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718908                                                           19     869
XP_005271621                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
XP_006712096                                                           17    2528
XP_006712095                                                           17    2528
XP_005264430                                                           17    2528
XP_006712094                                                           17    2528
XP_006712093                                                           17    2528
XP_005264429                                                           17    2528
NP_060022                                                              17    2528
NP_001229267                                                           17    2528
NP_066010                                                              17    3301
NP_057565                                                              16    5631
NP_006566                                                              16    5631
NP_942089                                                              16    5631
XP_006720077                                                           16    5631
XP_006720076                                                           16    5631
XP_005252107                                                           16    5631
XP_005252106                                                           16    5631
XP_005252105                                                           16    5631
XP_005252104                                                           16    5631
NP_001166203                                                           16    7355
NP_068557                                                              16    7355
NP_002174                                                              16    7355
NP_001254642                                                           16    7355
NP_001166210                                                           16    7355
NP_001166214                                                           16    7355
XP_005274838                                                           16    7355
XP_005274837                                                           16    7355
XP_006724523                                                           16    7355
XP_006724522                                                           16    7355
XP_005274489                                                           16    7355
XP_005274488                                                           16    7355
XP_006720778                                                           16    7355
XP_006720777                                                           16    7355
XP_006720776                                                           16    7355
XP_006720775                                                           16    7355
>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 2726 AVMQQVFQM 2734
>XP_006718908
          Length = 1708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 1378 AVMQQVFQM 1386
>XP_005271621
          Length = 2708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 2378 AVMQQVFQM 2386
>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 2720 AVMQQVFQM 2728
>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 2726 AVMQQVFQM 2734
>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 2726 AVMQQVFQM 2734
>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AVMQQVFPM 9
            AVMQQVF M
Sbjct: 2726 AVMQQVFQM 2734
>XP_006712096
          Length = 802

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  AVMQQVFP 8
          AV+Q+VFP
Sbjct: 36 AVLQKVFP 43
>XP_006712095
          Length = 849

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 706 AVLQKVFP 713
>XP_005264430
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 278 AVLQKVFP 285
>XP_006712094
          Length = 1067

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 706 AVLQKVFP 713
>XP_006712093
          Length = 1460

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 706 AVLQKVFP 713
>XP_005264429
          Length = 1472

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 706 AVLQKVFP 713
>NP_060022
          Length = 1458

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 692 AVLQKVFP 699
>NP_001229267
          Length = 1453

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AVMQQVFP 8
           AV+Q+VFP
Sbjct: 692 AVLQKVFP 699
>NP_066010
          Length = 1232

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VMQQVFPM 9
           ++QQVFP+
Sbjct: 204 IIQQVFPV 211
>NP_057565
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AVMQQVFPM 9
           A +QQ FPM
Sbjct: 238 ARIQQAFPM 246
>NP_006566
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           A M+Q+FP
Sbjct: 544 ATMEQLFP 551
>NP_942089
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           A M+Q+FP
Sbjct: 544 ATMEQLFP 551
>XP_006720077
          Length = 489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           A M+Q+FP
Sbjct: 187 ATMEQLFP 194
>XP_006720076
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           A M+Q+FP
Sbjct: 544 ATMEQLFP 551
>XP_005252107
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AVMQQVFPM 9
           A +QQ FPM
Sbjct: 92  ARIQQAFPM 100
>XP_005252106
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AVMQQVFPM 9
           A +QQ FPM
Sbjct: 92  ARIQQAFPM 100
>XP_005252105
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AVMQQVFPM 9
           A +QQ FPM
Sbjct: 92  ARIQQAFPM 100
>XP_005252104
          Length = 399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AVMQQVFPM 9
           A +QQ FPM
Sbjct: 238 ARIQQAFPM 246
>NP_001166203
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           AV+Q +FP
Sbjct: 136 AVLQNLFP 143
>NP_068557
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           AV+Q +FP
Sbjct: 186 AVLQNLFP 193
>NP_002174
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VMQQVFP 8
           VMQ++FP
Sbjct: 330 VMQRLFP 336
>NP_001254642
          Length = 300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VMQQVFP 8
           VMQ++FP
Sbjct: 252 VMQRLFP 258
>NP_001166210
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           AV+Q +FP
Sbjct: 186 AVLQNLFP 193
>NP_001166214
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           AV+Q +FP
Sbjct: 186 AVLQNLFP 193
>XP_005274838
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VMQQVFP 8
           VMQ++FP
Sbjct: 329 VMQRLFP 335
>XP_005274837
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VMQQVFP 8
           VMQ++FP
Sbjct: 330 VMQRLFP 336
>XP_006724523
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           AV+Q +FP
Sbjct: 186 AVLQNLFP 193
>XP_006724522
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AVMQQVFP 8
           AV+Q +FP
Sbjct: 186 AVLQNLFP 193
>XP_005274489
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VMQQVFP 8
           VMQ++FP
Sbjct: 329 VMQRLFP 335
>XP_005274488
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VMQQVFP 8
           VMQ++FP
Sbjct: 330 VMQRLFP 336
>XP_006720778
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  VMQQVFP 8
          V QQVFP
Sbjct: 72 VHQQVFP 78
>XP_006720777
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VMQQVFP 8
           V QQVFP
Sbjct: 106 VHQQVFP 112
>XP_006720776
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VMQQVFP 8
           V QQVFP
Sbjct: 189 VHQQVFP 195
>XP_006720775
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VMQQVFP 8
           V QQVFP
Sbjct: 311 VHQQVFP 317
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 414,816
Number of extensions: 388
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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