Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
NP_001002811                                                           18    1482
NP_001002812                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
NP_001138909                                                           17    4312
NP_002331                                                              17    4312
NP_001138908                                                           17    4312
NP_001001438                                                           17    4312
XP_006724066                                                           17    4312
NP_001004462                                                           16    5631
NP_612355                                                              16    5631
XP_006726657                                                           16    5631
XP_006725285                                                           16    5631
XP_005263588                                                           16    5631
NP_001001953                                                           16    5631
NP_001122405                                                           16    7355
NP_001122406                                                           16    7355
NP_001273683                                                           16    7355
NP_597734                                                              16    7355
NP_001155856                                                           15    9605
NP_004714                                                              15    9605
NP_001155855                                                           15    9605
NP_001230937                                                           15    9605
NP_004312                                                              15    9605
NP_071446                                                              15    9605
NP_112494                                                              15    9605
NP_061761                                                              15    9605
XP_006712668                                                           15    9605
XP_005247085                                                           15    9605
XP_005247084                                                           15    9605
XP_005247083                                                           15    9605
XP_006712667                                                           15    9605
XP_005247081                                                           15    9605
XP_005247080                                                           15    9605
XP_005247079                                                           15    9605
XP_006712666                                                           15    9605
XP_006712665                                                           15    9605
XP_006712664                                                           15    9605
XP_005245652                                                           15    9605
XP_006711689                                                           15    9605
XP_006711688                                                           15    9605
XP_006711687                                                           15    9605
XP_006711686                                                           15    9605
XP_005245651                                                           15    9605
XP_005245650                                                           15    9605
XP_005245649                                                           15    9605
XP_006711685                                                           15    9605
XP_005245648                                                           15    9605
XP_005245647                                                           15    9605
XP_005245646                                                           15    9605
XP_005245645                                                           15    9605
XP_005245644                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 900 VLLLREKV 907
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 834 VLLLREKV 841
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 834 VLLLREKV 841
>NP_001002811
          Length = 1132

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 834 VLLLREKV 841
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 900 VLLLREKV 907
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 900 VLLLREKV 907
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 900 VLLLREKV 907
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 834 VLLLREKV 841
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 834 VLLLREKV 841
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 837 VLLLREKV 844
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 900 VLLLREKV 907
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           VLLLREKV
Sbjct: 900 VLLLREKV 907
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VLLLREKV 9
            VLLLREKV
Sbjct: 997  VLLLREKV 1004
>NP_001138909
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AVLLLREK 8
           AVLLL+EK
Sbjct: 383 AVLLLQEK 390
>NP_002331
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AVLLLREK 8
           AVLLL+EK
Sbjct: 463 AVLLLQEK 470
>NP_001138908
          Length = 721

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AVLLLREK 8
           AVLLL+EK
Sbjct: 452 AVLLLQEK 459
>NP_001001438
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AVLLLREK 8
           AVLLL+EK
Sbjct: 463 AVLLLQEK 470
>XP_006724066
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AVLLLREK 8
           AVLLL+EK
Sbjct: 463 AVLLLQEK 470
>NP_001004462
          Length = 311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AVLLLREKV 9
           AVL LR+KV
Sbjct: 297 AVLKLRDKV 305
>NP_612355
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   AVLLLRE 7
           AVLLLRE
Sbjct: 140 AVLLLRE 146
>XP_006726657
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   AVLLLRE 7
           AVLLLRE
Sbjct: 140 AVLLLRE 146
>XP_006725285
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   AVLLLRE 7
           AVLLLRE
Sbjct: 140 AVLLLRE 146
>XP_005263588
          Length = 667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   AVLLLRE 7
           AVLLLRE
Sbjct: 140 AVLLLRE 146
>NP_001001953
          Length = 311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AVLLLREKV 9
           AVL LR+KV
Sbjct: 297 AVLKLRDKV 305
>NP_001122405
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLLREKV 9
           L+LREKV
Sbjct: 182 LILREKV 188
>NP_001122406
          Length = 1109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLLREKV 9
           L+LREKV
Sbjct: 182 LILREKV 188
>NP_001273683
          Length = 1230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLLREKV 9
           L+LREKV
Sbjct: 151 LILREKV 157
>NP_597734
          Length = 1261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLLREKV 9
           L+LREKV
Sbjct: 182 LILREKV 188
>NP_001155856
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 604 VELLREKV 611
>NP_004714
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 577 VELLREKV 584
>NP_001155855
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 605 VELLREKV 612
>NP_001230937
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1496 LLLREKL 1502
>NP_004312
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1395 LLLREKL 1401
>NP_071446
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLLLREK 8
           VLL+REK
Sbjct: 158 VLLVREK 164
>NP_112494
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLLREKV 9
           +LLL+EK+
Sbjct: 384 ILLLKEKL 391
>NP_061761
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLLREKV 9
          LLLREK+
Sbjct: 83 LLLREKL 89
>XP_006712668
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1487 LLLREKL 1493
>XP_005247085
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1395 LLLREKL 1401
>XP_005247084
          Length = 1698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1403 LLLREKL 1409
>XP_005247083
          Length = 1699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1404 LLLREKL 1410
>XP_006712667
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1438 LLLREKL 1444
>XP_005247081
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1496 LLLREKL 1502
>XP_005247080
          Length = 1799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1504 LLLREKL 1510
>XP_005247079
          Length = 1800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1505 LLLREKL 1511
>XP_006712666
          Length = 1816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1521 LLLREKL 1527
>XP_006712665
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1529 LLLREKL 1535
>XP_006712664
          Length = 1825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLLREKV 9
            LLLREK+
Sbjct: 1530 LLLREKL 1536
>XP_005245652
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 426 VELLREKV 433
>XP_006711689
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 529 VELLREKV 536
>XP_006711688
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 529 VELLREKV 536
>XP_006711687
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 529 VELLREKV 536
>XP_006711686
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 529 VELLREKV 536
>XP_005245651
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 578 VELLREKV 585
>XP_005245650
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 578 VELLREKV 585
>XP_005245649
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 578 VELLREKV 585
>XP_006711685
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 588 VELLREKV 595
>XP_005245648
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 590 VELLREKV 597
>XP_005245647
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 590 VELLREKV 597
>XP_005245646
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 597 VELLREKV 604
>XP_005245645
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 604 VELLREKV 611
>XP_005245644
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VLLLREKV 9
           V LLREKV
Sbjct: 605 VELLREKV 612
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.147    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 513,039
Number of extensions: 750
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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