Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_001005210                                                           17    2528
NP_808882                                                              16    5631
NP_001137544                                                           16    5631
XP_006720011                                                           16    5631
XP_006720010                                                           16    5631
NP_443165                                                              16    7355
NP_078808                                                              15    9605
NP_001020607                                                           15    9605
NP_060264                                                              15    9605
NP_690043                                                              15    9605
NP_000780                                                              15    9605
NP_001171528                                                           15    9605
NP_001254726                                                           15    9605
NP_758519                                                              15    9605
NP_000751                                                              15    9605
NP_724781                                                              15    9605
NP_055630                                                              15    9605
XP_005257931                                                           15    9605
XP_005257930                                                           15    9605
XP_005257929                                                           15    9605
XP_006722270                                                           15    9605
XP_006722269                                                           15    9605
XP_005257928                                                           15    9605
XP_006722268                                                           15    9605
XP_005257927                                                           15    9605
XP_006722267                                                           15    9605
XP_006722266                                                           15    9605
XP_006721800                                                           15    9605
XP_005257167                                                           15    9605
XP_005251551                                                           15    9605
XP_006716857                                                           15    9605
XP_006712810                                                           15    9605
XP_006712809                                                           15    9605
XP_006712808                                                           15    9605
XP_005270552                                                           15    9605
XP_005270550                                                           15    9605
XP_005270549                                                           15    9605
NP_001072986                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ATNFLLKMT 9
            ATNFLL+MT
Sbjct: 2558 ATNFLLEMT 2566
>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ATNFLLKMT 9
            ATNFLL+MT
Sbjct: 2558 ATNFLLEMT 2566
>NP_001005210
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ATNFLLKMT 9
           ATNFLL +T
Sbjct: 317 ATNFLLGIT 325
>NP_808882
          Length = 309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ATNFLLK 7
           ATNFLL+
Sbjct: 302 ATNFLLQ 308
>NP_001137544
          Length = 344

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ATNFLLK 7
           ATNFLL+
Sbjct: 337 ATNFLLQ 343
>XP_006720011
          Length = 231

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ATNFLLK 7
           ATNFLL+
Sbjct: 224 ATNFLLQ 230
>XP_006720010
          Length = 262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ATNFLLK 7
           ATNFLL+
Sbjct: 255 ATNFLLQ 261
>NP_443165
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TNFLLKMT 9
          T+F+LK+T
Sbjct: 81 TSFMLKVT 88
>NP_078808
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 115 NFLIKM 120
>NP_001020607
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 115 NFLIKM 120
>NP_060264
          Length = 1801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NF+LKM
Sbjct: 815 NFILKM 820
>NP_690043
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 476 NFLMKM 481
>NP_000780
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    NFLLKM 8
            NFL+KM
Sbjct: 1050 NFLMKM 1055
>NP_001171528
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 476 NFLMKM 481
>NP_001254726
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 324 AFEFLLKLT 332
>NP_758519
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ATNFLLK 7
           AT FLLK
Sbjct: 485 ATGFLLK 491
>NP_000751
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ATNFLLK 7
           AT FLLK
Sbjct: 485 ATGFLLK 491
>NP_724781
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ATNFLLK 7
           AT FLLK
Sbjct: 485 ATGFLLK 491
>NP_055630
          Length = 989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 337 AFEFLLKLT 345
>XP_005257931
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 362 AFEFLLKLT 370
>XP_005257930
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 381 AFEFLLKLT 389
>XP_005257929
          Length = 1033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 381 AFEFLLKLT 389
>XP_006722270
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 337 AFEFLLKLT 345
>XP_006722269
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 337 AFEFLLKLT 345
>XP_005257928
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 356 AFEFLLKLT 364
>XP_006722268
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 356 AFEFLLKLT 364
>XP_005257927
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 362 AFEFLLKLT 370
>XP_006722267
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 362 AFEFLLKLT 370
>XP_006722266
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 381 AFEFLLKLT 389
>XP_006721800
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 360 NFLMKM 365
>XP_005257167
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 867 NFLMKM 872
>XP_005251551
          Length = 1801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NF+LKM
Sbjct: 815 NFILKM 820
>XP_006716857
          Length = 1834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NF+LKM
Sbjct: 848 NFILKM 853
>XP_006712810
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 115 NFLIKM 120
>XP_006712809
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 115 NFLIKM 120
>XP_006712808
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NFLLKM 8
           NFL+KM
Sbjct: 115 NFLIKM 120
>XP_005270552
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ATNFLLK 7
           AT FLLK
Sbjct: 353 ATGFLLK 359
>XP_005270550
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ATNFLLK 7
           AT FLLK
Sbjct: 485 ATGFLLK 491
>XP_005270549
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ATNFLLK 7
           AT FLLK
Sbjct: 463 ATGFLLK 469
>NP_001072986
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATNFLLKMT 9
           A  FLLK+T
Sbjct: 324 AFEFLLKLT 332
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.131    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 424,562
Number of extensions: 648
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package