Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              20     509
NP_057340                                                              17    4312
NP_001127911                                                           16    5631
NP_001127910                                                           16    5631
NP_665696                                                              16    5631
NP_001127909                                                           16    5631
NP_065176                                                              16    7355
NP_060233                                                              16    7355
NP_056240                                                              16    7355
XP_006717609                                                           16    7355
XP_006712046                                                           16    7355
XP_006711671                                                           16    7355
XP_006711670                                                           16    7355
XP_005245629                                                           16    7355
NP_055084                                                              15    9605
NP_001265055                                                           15    9605
NP_001265056                                                           15    9605
NP_001124177                                                           15    9605
NP_001124175                                                           15    9605
NP_001124176                                                           15    9605
NP_000952                                                              15    9605
NP_060896                                                              15    9605
NP_004433                                                              15    9605
NP_059145                                                              15    9605
NP_001265054                                                           15    9605
NP_054786                                                              15    9605
NP_001073922                                                           15    9605
NP_001272378                                                           15    9605
NP_001272376                                                           15    9605
NP_001272374                                                           15    9605
NP_001272373                                                           15    9605
NP_660308                                                              15    9605
NP_055842                                                              15    9605
NP_001272377                                                           15    9605
NP_001272379                                                           15    9605
XP_006726664                                                           15    9605
XP_006726663                                                           15    9605
XP_006726662                                                           15    9605
XP_006726661                                                           15    9605
XP_006726660                                                           15    9605
XP_006726659                                                           15    9605
XP_006726658                                                           15    9605
XP_006726602                                                           15    9605
XP_006725292                                                           15    9605
XP_006725291                                                           15    9605
XP_006725290                                                           15    9605
XP_006725289                                                           15    9605
XP_006725288                                                           15    9605
XP_006725287                                                           15    9605
XP_006725286                                                           15    9605
XP_006720929                                                           15    9605
XP_005255233                                                           15    9605
XP_006720928                                                           15    9605
XP_005255231                                                           15    9605
XP_005255230                                                           15    9605
XP_006719236                                                           15    9605
XP_005273996                                                           15    9605
XP_005249274                                                           15    9605
XP_005249273                                                           15    9605
XP_005249272                                                           15    9605
XP_005249271                                                           15    9605
XP_006715198                                                           15    9605
XP_005249269                                                           15    9605
XP_005249270                                                           15    9605
XP_005249268                                                           15    9605
XP_005248303                                                           15    9605
XP_005262762                                                           15    9605
XP_005262761                                                           15    9605
XP_006710505                                                           15    9605
XP_006710504                                                           15    9605
XP_006710021                                                           15    9605
>NP_003290
          Length = 803

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           ATLRSGYL
Sbjct: 721 ATLRSGYL 728
>NP_057340
          Length = 515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ATLRSGYLS 9
           ATLR+G LS
Sbjct: 435 ATLRAGELS 443
>NP_001127911
          Length = 1253

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLRSGYLS 9
           TL+ GY+S
Sbjct: 826 TLKEGYIS 833
>NP_001127910
          Length = 1253

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLRSGYLS 9
           TL+ GY+S
Sbjct: 826 TLKEGYIS 833
>NP_665696
          Length = 1210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLRSGYLS 9
           TL+ GY+S
Sbjct: 783 TLKEGYIS 790
>NP_001127909
          Length = 1237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLRSGYLS 9
           TL+ GY+S
Sbjct: 810 TLKEGYIS 817
>NP_065176
          Length = 1877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRSGYLS 9
           L+SGY+S
Sbjct: 385 LKSGYMS 391
>NP_060233
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLRSGYLS 9
           T RSGYL+
Sbjct: 452 TERSGYLA 459
>NP_056240
          Length = 1720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TLRSGYL 8
           T RSGYL
Sbjct: 982 TSRSGYL 988
>XP_006717609
          Length = 290

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ATLRSGY 7
          ATLR GY
Sbjct: 46 ATLRIGY 52
>XP_006712046
          Length = 1612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TLRSGYL 8
           T RSGYL
Sbjct: 874 TSRSGYL 880
>XP_006711671
          Length = 2153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRSGYLS 9
           L+SGY+S
Sbjct: 672 LKSGYMS 678
>XP_006711670
          Length = 2161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRSGYLS 9
           L+SGY+S
Sbjct: 672 LKSGYMS 678
>XP_005245629
          Length = 2164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRSGYLS 9
           L+SGY+S
Sbjct: 672 LKSGYMS 678
>NP_055084
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_001265055
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_001265056
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_001124177
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_001124175
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_001124176
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_000952
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LRSGYLS 9
           LR+GYL+
Sbjct: 173 LRAGYLT 179
>NP_060896
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 699 STMRTGFLA 707
>NP_004433
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLRSGY 7
           TL+SGY
Sbjct: 655 TLKSGY 660
>NP_059145
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLRSGY 7
           TL+SGY
Sbjct: 654 TLKSGY 659
>NP_001265054
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>NP_054786
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           A LRS YLS
Sbjct: 241 AELRSCYLS 249
>NP_001073922
          Length = 2190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ATLRSG 6
            ATLRSG
Sbjct: 1526 ATLRSG 1531
>NP_001272378
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 275 ATLALGYVS 283
>NP_001272376
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 260 ATLALGYVS 268
>NP_001272374
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 247 ATLALGYVS 255
>NP_001272373
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 248 ATLALGYVS 256
>NP_660308
          Length = 260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LRSGYLS 9
           LRS YLS
Sbjct: 137 LRSAYLS 143
>NP_055842
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 275 ATLALGYVS 283
>NP_001272377
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 184 ATLALGYVS 192
>NP_001272379
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 252 ATLALGYVS 260
>XP_006726664
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 293 ATLALGYVS 301
>XP_006726663
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 248 ATLALGYVS 256
>XP_006726662
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 260 ATLALGYVS 268
>XP_006726661
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 266 ATLALGYVS 274
>XP_006726660
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 275 ATLALGYVS 283
>XP_006726659
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 284 ATLALGYVS 292
>XP_006726658
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 293 ATLALGYVS 301
>XP_006726602
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ATLRSG 6
          ATLRSG
Sbjct: 33 ATLRSG 38
>XP_006725292
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 293 ATLALGYVS 301
>XP_006725291
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 248 ATLALGYVS 256
>XP_006725290
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 260 ATLALGYVS 268
>XP_006725289
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 266 ATLALGYVS 274
>XP_006725288
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 275 ATLALGYVS 283
>XP_006725287
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 284 ATLALGYVS 292
>XP_006725286
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 293 ATLALGYVS 301
>XP_006720929
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 293 ATLALGYVS 301
>XP_005255233
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 260 ATLALGYVS 268
>XP_006720928
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 266 ATLALGYVS 274
>XP_005255231
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 284 ATLALGYVS 292
>XP_005255230
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           ATL  GY+S
Sbjct: 293 ATLALGYVS 301
>XP_006719236
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ATLRSG 6
          ATLRSG
Sbjct: 33 ATLRSG 38
>XP_005273996
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ATLRSGYLS 9
           A LRS YLS
Sbjct: 241 AELRSCYLS 249
>XP_005249274
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 699 STMRTGFLA 707
>XP_005249273
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 681 STMRTGFLA 689
>XP_005249272
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 686 STMRTGFLA 694
>XP_005249271
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 695 STMRTGFLA 703
>XP_006715198
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 699 STMRTGFLA 707
>XP_005249269
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 699 STMRTGFLA 707
>XP_005249270
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 699 STMRTGFLA 707
>XP_005249268
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ATLRSGYLS 9
           +T+R+G+L+
Sbjct: 708 STMRTGFLA 716
>XP_005248303
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LRSGYLS 9
           LRS YLS
Sbjct: 176 LRSAYLS 182
>XP_005262762
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>XP_005262761
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATLRSGYL 8
           +T+RSG++
Sbjct: 160 STMRSGFM 167
>XP_006710505
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLRSGY 7
           TL+SGY
Sbjct: 624 TLKSGY 629
>XP_006710504
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLRSGY 7
           TL+SGY
Sbjct: 648 TLKSGY 653
>XP_006710021
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ATLRSG 6
          ATLRSG
Sbjct: 33 ATLRSG 38
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.127    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 515,780
Number of extensions: 571
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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