Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_001077415                                                           17    2528
XP_005264468                                                           17    2528
XP_005264467                                                           17    2528
NP_653337                                                              17    2528
NP_689982                                                              17    3301
XP_006722779                                                           17    3301
XP_006722778                                                           17    3301
XP_005259585                                                           17    3301
XP_006722777                                                           17    3301
NP_071394                                                              17    4312
NP_001177410                                                           17    4312
NP_997244                                                              16    5631
NP_056141                                                              16    5631
NP_001164108                                                           16    5631
NP_001004729                                                           16    5631
NP_055764                                                              16    5631
XP_005277570                                                           16    5631
XP_005277569                                                           16    5631
XP_006711309                                                           16    5631
XP_005277568                                                           16    5631
XP_005277567                                                           16    5631
NP_000194                                                              16    7355
NP_001243725                                                           16    7355
NP_612154                                                              16    7355
NP_060876                                                              16    7355
NP_004523                                                              16    7355
NP_001248327                                                           16    7355
NP_002551                                                              16    7355
XP_006713944                                                           16    7355
NP_055414                                                              15    9605
NP_001071107                                                           15    9605
NP_957516                                                              15    9605
NP_872301                                                              15    9605
NP_803182                                                              15    9605
NP_945343                                                              15    9605
XP_006718928                                                           15    9605
XP_006718829                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1313 ATCRSTSFN 1321
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1313 ATCRSTSFN 1321
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1382 ATCRSTSFN 1390
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1382 ATCRSTSFN 1390
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1323 ATCRSTSFN 1331
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1392 ATCRSTSFN 1400
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1392 ATCRSTSFN 1400
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATGRSTSFN 9
            AT RSTSFN
Sbjct: 1392 ATCRSTSFN 1400
>NP_001077415
          Length = 343

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  ATGRSTSF 8
          ATG+ST+F
Sbjct: 84 ATGKSTAF 91
>XP_005264468
          Length = 370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ATGRSTSF 8
           ATG+ST+F
Sbjct: 111 ATGKSTAF 118
>XP_005264467
          Length = 399

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  ATGRSTSF 8
          ATG+ST+F
Sbjct: 69 ATGKSTAF 76
>NP_653337
          Length = 441

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ATGRSTSF 8
           ATG+ST+F
Sbjct: 111 ATGKSTAF 118
>NP_689982
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  SFN
Sbjct: 127 STGRRVSFN 135
>XP_006722779
          Length = 335

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  SFN
Sbjct: 173 STGRRVSFN 181
>XP_006722778
          Length = 499

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  SFN
Sbjct: 173 STGRRVSFN 181
>XP_005259585
          Length = 705

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  SFN
Sbjct: 127 STGRRVSFN 135
>XP_006722777
          Length = 751

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  SFN
Sbjct: 173 STGRRVSFN 181
>NP_071394
          Length = 1339

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TGRSTSF 8
           TGR TSF
Sbjct: 793 TGRGTSF 799
>NP_001177410
          Length = 1275

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TGRSTSF 8
           TGR TSF
Sbjct: 729 TGRGTSF 735
>NP_997244
          Length = 3169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TGRSTSF 8
          TG STSF
Sbjct: 14 TGNSTSF 20
>NP_056141
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 926 GRSKSFN 932
>NP_001164108
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 925 GRSKSFN 931
>NP_001004729
          Length = 311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           A GRS +FN
Sbjct: 232 AKGRSKAFN 240
>NP_055764
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           ATG S +FN
Sbjct: 190 ATGTSPTFN 198
>XP_005277570
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 773 GRSKSFN 779
>XP_005277569
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 773 GRSKSFN 779
>XP_006711309
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 926 GRSKSFN 932
>XP_005277568
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 925 GRSKSFN 931
>XP_005277567
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GRSTSFN 9
           GRS SFN
Sbjct: 926 GRSKSFN 932
>NP_000194
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  S+N
Sbjct: 102 STGRGLSYN 110
>NP_001243725
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  +FN
Sbjct: 161 STGRCVAFN 169
>NP_612154
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATGRSTSF 8
           +TGR T+F
Sbjct: 118 STGRGTTF 125
>NP_060876
          Length = 5412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ATGRSTSF 8
            +TGR T+F
Sbjct: 4405 STGRGTTF 4412
>NP_004523
          Length = 1176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATGRSTSF 8
           +TGR T+F
Sbjct: 169 STGRGTTF 176
>NP_001248327
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  +FN
Sbjct: 145 STGRCVAFN 153
>NP_002551
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  +FN
Sbjct: 145 STGRCVAFN 153
>XP_006713944
          Length = 722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TGR  S+N
Sbjct: 102 STGRGLSYN 110
>NP_055414
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TG STS N
Sbjct: 548 STGASTSTN 556
>NP_001071107
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           A+G+ T FN
Sbjct: 151 ASGKVTDFN 159
>NP_957516
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TG STS N
Sbjct: 548 STGASTSTN 556
>NP_872301
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           A+G+ T FN
Sbjct: 163 ASGKVTDFN 171
>NP_803182
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           +TG STS N
Sbjct: 548 STGASTSTN 556
>NP_945343
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GRSTSFN 9
           GR+TSF+
Sbjct: 503 GRATSFD 509
>XP_006718928
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           A+G+ T FN
Sbjct: 151 ASGKVTDFN 159
>XP_006718829
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATGRSTSFN 9
           A+G+ T FN
Sbjct: 157 ASGKVTDFN 165
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.113    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 494,830
Number of extensions: 830
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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