Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              20     299
NP_631894                                                              17    4312
NP_542453                                                              17    4312
NP_055661                                                              16    5631
NP_001091952                                                           16    5631
NP_056136                                                              16    5631
NP_056099                                                              16    5631
NP_057253                                                              16    5631
NP_004657                                                              16    5631
NP_058642                                                              16    5631
NP_065744                                                              16    5631
NP_061859                                                              16    5631
XP_006722773                                                           16    5631
XP_005259893                                                           16    5631
XP_005259892                                                           16    5631
XP_005259891                                                           16    5631
XP_005259890                                                           16    5631
XP_006717955                                                           16    5631
XP_006713954                                                           16    5631
XP_006713953                                                           16    5631
XP_006713952                                                           16    5631
XP_005248031                                                           16    5631
XP_006713951                                                           16    5631
XP_006710564                                                           16    5631
XP_005270743                                                           16    5631
NP_981951                                                              16    5631
NP_065861                                                              16    7355
NP_001135993                                                           16    7355
NP_001135991                                                           16    7355
NP_071357                                                              16    7355
NP_942144                                                              16    7355
NP_001135992                                                           16    7355
XP_006726770                                                           16    7355
XP_006726769                                                           16    7355
XP_006724601                                                           16    7355
XP_006721680                                                           16    7355
XP_006721679                                                           16    7355
XP_005267973                                                           16    7355
XP_006710082                                                           16    7355
XP_006710081                                                           16    7355
NP_000029                                                              15    9605
NP_001120983                                                           15    9605
NP_001120982                                                           15    9605
NP_001073946                                                           15    9605
NP_938080                                                              15    9605
NP_055458                                                              15    9605
NP_004659                                                              15    9605
NP_000180                                                              15    9605
NP_037411                                                              15    9605
NP_001120864                                                           15    9605
XP_005274286                                                           15    9605
XP_005274285                                                           15    9605
XP_005274284                                                           15    9605
XP_005274283                                                           15    9605
XP_005274282                                                           15    9605
XP_005274281                                                           15    9605
XP_005274280                                                           15    9605
XP_005274279                                                           15    9605
XP_006716232                                                           15    9605
XP_006716231                                                           15    9605
XP_006714321                                                           15    9605
XP_006714320                                                           15    9605
XP_006714319                                                           15    9605
XP_005264337                                                           15    9605
>NP_002430
          Length = 1137

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ATGDVVFDS 9
           ATG+VVFDS
Sbjct: 396 ATGEVVFDS 404
>NP_631894
          Length = 1226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGDVVF
Sbjct: 658 TGDVVF 663
>NP_542453
          Length = 1223

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGDVVF
Sbjct: 655 TGDVVF 660
>NP_055661
          Length = 1159

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  GDVVFD 8
          GD++FD
Sbjct: 52 GDIIFD 57
>NP_001091952
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 601 GDVSFDS 607
>NP_056136
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 585 GDVSFDS 591
>NP_056099
          Length = 3375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATGDVVFD 8
           +TG+++FD
Sbjct: 112 STGEILFD 119
>NP_057253
          Length = 484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DVVFDS 9
           DVVFDS
Sbjct: 476 DVVFDS 481
>NP_004657
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DVVFDS 9
           DVVFDS
Sbjct: 163 DVVFDS 168
>NP_058642
          Length = 299

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TGDVVFD 8
           TG++VFD
Sbjct: 194 TGELVFD 200
>NP_065744
          Length = 2113

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ATGDVVFD 8
           ATGD ++D
Sbjct: 122 ATGDDIYD 129
>NP_061859
          Length = 1336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    ATGDVVFD 8
            A GD+ FD
Sbjct: 1115 AAGDIFFD 1122
>XP_006722773
          Length = 512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 463 GDVSFDS 469
>XP_005259893
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 480 GDVSFDS 486
>XP_005259892
          Length = 564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 515 GDVSFDS 521
>XP_005259891
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 556 GDVSFDS 562
>XP_005259890
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GDV FDS
Sbjct: 572 GDVSFDS 578
>XP_006717955
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DVVFDS 9
           DVVFDS
Sbjct: 374 DVVFDS 379
>XP_006713954
          Length = 1043

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ATGDVVFD 8
           A GD+ FD
Sbjct: 822 AAGDIFFD 829
>XP_006713953
          Length = 1043

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ATGDVVFD 8
           A GD+ FD
Sbjct: 822 AAGDIFFD 829
>XP_006713952
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ATGDVVFD 8
           A GD+ FD
Sbjct: 944 AAGDIFFD 951
>XP_005248031
          Length = 1260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    ATGDVVFD 8
            A GD+ FD
Sbjct: 1039 AAGDIFFD 1046
>XP_006713951
          Length = 1309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    ATGDVVFD 8
            A GD+ FD
Sbjct: 1088 AAGDIFFD 1095
>XP_006710564
          Length = 3432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATGDVVFD 8
           +TG+++FD
Sbjct: 112 STGEILFD 119
>XP_005270743
          Length = 3453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ATGDVVFD 8
           +TG+++FD
Sbjct: 133 STGEILFD 140
>NP_981951
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TGDVVFD 8
           +GDVV+D
Sbjct: 187 SGDVVYD 193
>NP_065861
          Length = 509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GDVVFD 8
           GDV+FD
Sbjct: 299 GDVLFD 304
>NP_001135993
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGDVVFDS 9
           A+G  VFDS
Sbjct: 540 ASGSPVFDS 548
>NP_001135991
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGDVVFDS 9
           A+G  VFDS
Sbjct: 540 ASGSPVFDS 548
>NP_071357
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGDVVFDS 9
           A+G  VFDS
Sbjct: 540 ASGSPVFDS 548
>NP_942144
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGDVVFDS 9
           A+G  VFDS
Sbjct: 540 ASGSPVFDS 548
>NP_001135992
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATGDVVFDS 9
           A+G  VFDS
Sbjct: 540 ASGSPVFDS 548
>XP_006726770
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ATGDVVFDS 9
          +TG VV+D+
Sbjct: 7  STGHVVYDA 15
>XP_006726769
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ATGDVVFDS 9
          +TG VV+D+
Sbjct: 7  STGHVVYDA 15
>XP_006724601
          Length = 1020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DVVFDS 9
           DV+FDS
Sbjct: 700 DVIFDS 705
>XP_006721680
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ATGDVVFDS 9
          +TG VV+D+
Sbjct: 7  STGHVVYDA 15
>XP_006721679
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ATGDVVFDS 9
          +TG VV+D+
Sbjct: 7  STGHVVYDA 15
>XP_005267973
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GDVVFD 8
           GDV+FD
Sbjct: 327 GDVLFD 332
>XP_006710082
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ATGDVVFDS 9
          +TG VV+D+
Sbjct: 7  STGHVVYDA 15
>XP_006710081
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ATGDVVFDS 9
          +TG VV+D+
Sbjct: 7  STGHVVYDA 15
>NP_000029
          Length = 2843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GD VFD+
Sbjct: 797 GDYVFDT 803
>NP_001120983
          Length = 2825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GD VFD+
Sbjct: 779 GDYVFDT 785
>NP_001120982
          Length = 2843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GDVVFDS 9
           GD VFD+
Sbjct: 797 GDYVFDT 803
>NP_001073946
          Length = 2699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ATGDVVFDS 9
            A G++ FDS
Sbjct: 2320 AYGEIYFDS 2328
>NP_938080
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ATGDVV 6
           ATGDV+
Sbjct: 228 ATGDVI 233
>NP_055458
          Length = 1163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   GDVVFD 8
           GDV FD
Sbjct: 445 GDVAFD 450
>NP_004659
          Length = 1857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ATGDVVFDS 9
            +TG +++DS
Sbjct: 1100 STGTIIWDS 1108
>NP_000180
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TGDVVFD 8
           TGD +FD
Sbjct: 570 TGDELFD 576
>NP_037411
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 643 TGDMVF 648
>NP_001120864
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_005274286
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 538 TGDMVF 543
>XP_005274285
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 601 TGDMVF 606
>XP_005274284
          Length = 1120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_005274283
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_005274282
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_005274281
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_005274280
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_005274279
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TGDVVF 7
           TGD+VF
Sbjct: 652 TGDMVF 657
>XP_006716232
          Length = 2753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ATGDVVFDS 9
            +TG +++DS
Sbjct: 1100 STGTIIWDS 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ATGDVVFDS 9
            +TG +++DS
Sbjct: 1996 STGTIIWDS 2004
>XP_006716231
          Length = 2753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ATGDVVFDS 9
            +TG +++DS
Sbjct: 1100 STGTIIWDS 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ATGDVVFDS 9
            +TG +++DS
Sbjct: 1996 STGTIIWDS 2004
>XP_006714321
          Length = 2713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ATGDVVFDS 9
            A G++ FDS
Sbjct: 2334 AYGEIYFDS 2342
>XP_006714320
          Length = 2720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ATGDVVFDS 9
            A G++ FDS
Sbjct: 2341 AYGEIYFDS 2349
>XP_006714319
          Length = 2721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ATGDVVFDS 9
            A G++ FDS
Sbjct: 2342 AYGEIYFDS 2350
>XP_005264337
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TGDVVFD 8
           TGD +FD
Sbjct: 570 TGDELFD 576
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.134    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 599,996
Number of extensions: 1087
Number of successful extensions: 66
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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