Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              19     869
XP_006713721                                                           19     869
NP_001269356                                                           18    1135
NP_001269355                                                           18    1135
NP_002640                                                              18    1135
XP_005250500                                                           18    1135
NP_005017                                                              17    2528
XP_006710753                                                           17    2528
XP_005263530                                                           17    2528
XP_006710752                                                           17    2528
XP_006710751                                                           17    2528
XP_006710750                                                           17    2528
XP_006710749                                                           17    2528
NP_002636                                                              17    3301
XP_005253037                                                           17    3301
XP_005253036                                                           17    3301
XP_005253035                                                           17    3301
XP_005253034                                                           17    3301
XP_005245315                                                           17    3301
XP_006711447                                                           17    3301
XP_005245314                                                           17    3301
NP_002637                                                              17    3301
NP_001275701                                                           17    4312
NP_004561                                                              17    4312
NP_079130                                                              17    4312
NP_078838                                                              17    4312
NP_001275703                                                           17    4312
XP_006719216                                                           17    4312
XP_005253450                                                           17    4312
XP_006719151                                                           17    4312
NP_001139753                                                           16    5631
NP_001139751                                                           16    5631
NP_001276042                                                           16    5631
NP_001276043                                                           16    5631
NP_001139752                                                           16    5631
NP_001031                                                              16    5631
NP_001276044                                                           16    5631
XP_005256822                                                           16    5631
XP_005256819                                                           16    5631
XP_006721632                                                           16    5631
NP_004095                                                              16    7355
NP_002638                                                              16    7355
NP_898884                                                              16    7355
XP_006713666                                                           16    7355
XP_006713665                                                           16    7355
NP_055597                                                              15    9605
NP_808818                                                              15    9605
NP_001269160                                                           15    9605
NP_001122062                                                           15    9605
NP_000491                                                              15    9605
XP_006726139                                                           15    9605
XP_006725959                                                           15    9605
XP_006725535                                                           15    9605
XP_005278172                                                           15    9605
XP_005278173                                                           15    9605
XP_005278170                                                           15    9605
XP_005278174                                                           15    9605
XP_005278168                                                           15    9605
XP_005278166                                                           15    9605
XP_005278171                                                           15    9605
XP_005278167                                                           15    9605
XP_006715064                                                           15    9605
>NP_006209
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           ATFILGI D
Sbjct: 907 ATFILGIGD 915
>XP_006713721
          Length = 1068

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           ATFILGI D
Sbjct: 907 ATFILGIGD 915
>NP_001269356
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           ATF+LGI D
Sbjct: 938 ATFVLGIGD 946
>NP_001269355
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           ATF+LGI D
Sbjct: 938 ATFVLGIGD 946
>NP_002640
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           ATF+LGI D
Sbjct: 938 ATFVLGIGD 946
>XP_005250500
          Length = 1102

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           ATF+LGI D
Sbjct: 938 ATFVLGIGD 946
>NP_005017
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 885 ATYVLGIGD 893
>XP_006710753
          Length = 1015

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 856 ATYVLGIGD 864
>XP_005263530
          Length = 1043

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 884 ATYVLGIGD 892
>XP_006710752
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 885 ATYVLGIGD 893
>XP_006710751
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 885 ATYVLGIGD 893
>XP_006710750
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 885 ATYVLGIGD 893
>XP_006710749
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 885 ATYVLGIGD 893
>NP_002636
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1242 ATYVLGICD 1250
>XP_005253037
          Length = 1306

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ATFILGIRD 9
           AT++LGI D
Sbjct: 862 ATYVLGICD 870
>XP_005253036
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1242 ATYVLGICD 1250
>XP_005253035
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1242 ATYVLGICD 1250
>XP_005253034
          Length = 1686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1242 ATYVLGICD 1250
>XP_005245315
          Length = 1607

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1160 ATYVLGICD 1168
>XP_006711447
          Length = 1634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1187 ATYVLGICD 1195
>XP_005245314
          Length = 1634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1187 ATYVLGICD 1195
>NP_002637
          Length = 1634

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ATFILGIRD 9
            AT++LGI D
Sbjct: 1187 ATYVLGICD 1195
>NP_001275701
          Length = 1486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TFILGIRD 9
            TFILG+ D
Sbjct: 1067 TFILGVCD 1074
>NP_004561
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TFILGIRD 9
            TFILG+ D
Sbjct: 1026 TFILGVCD 1033
>NP_079130
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           ++LGIRD
Sbjct: 127 YVLGIRD 133
>NP_078838
          Length = 1094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TFILGIRD 9
           TF+ G+RD
Sbjct: 961 TFLRGVRD 968
>NP_001275703
          Length = 1264

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TFILGIRD 9
           TFILG+ D
Sbjct: 845 TFILGVCD 852
>XP_006719216
          Length = 259

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           ++LGIRD
Sbjct: 127 YVLGIRD 133
>XP_005253450
          Length = 1486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TFILGIRD 9
            TFILG+ D
Sbjct: 1067 TFILGVCD 1074
>XP_006719151
          Length = 1486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TFILGIRD 9
            TFILG+ D
Sbjct: 1067 TFILGVCD 1074
>NP_001139753
          Length = 287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>NP_001139751
          Length = 384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>NP_001276042
          Length = 344

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FILGIRD 9
          F+LG+RD
Sbjct: 38 FMLGLRD 44
>NP_001276043
          Length = 344

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FILGIRD 9
          F+LG+RD
Sbjct: 38 FMLGLRD 44
>NP_001139752
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>NP_001031
          Length = 402

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>NP_001276044
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FILGIRD 9
          F+LG+RD
Sbjct: 38 FMLGLRD 44
>XP_005256822
          Length = 233

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>XP_005256819
          Length = 239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>XP_006721632
          Length = 348

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FILGIRD 9
           F+LG+RD
Sbjct: 96  FMLGLRD 102
>NP_004095
          Length = 2511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    ILGIRD 9
            ILGIRD
Sbjct: 2134 ILGIRD 2139
>NP_002638
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TFILGIRD 9
           T+ILG+ D
Sbjct: 736 TYILGVGD 743
>NP_898884
          Length = 1177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATFILGIRD 9
           A  ILG+RD
Sbjct: 422 AVTILGLRD 430
>XP_006713666
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATFILGIRD 9
           A  ILG+RD
Sbjct: 349 AVTILGLRD 357
>XP_006713665
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ATFILGIRD 9
           A  ILG+RD
Sbjct: 422 AVTILGLRD 430
>NP_055597
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>NP_808818
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>NP_001269160
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>NP_001122062
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATFILGIRD 9
           +  +LGIRD
Sbjct: 96  SALLLGIRD 104
>NP_000491
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ATFILGIRD 9
           +  +LGIRD
Sbjct: 126 SALLLGIRD 134
>XP_006726139
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ATFILGIRD 9
          +  +LGIRD
Sbjct: 85 SALLLGIRD 93
>XP_006725959
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ATFILGIRD 9
          +  +LGIRD
Sbjct: 85 SALLLGIRD 93
>XP_006725535
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ATFILGIRD 9
          +  +LGIRD
Sbjct: 85 SALLLGIRD 93
>XP_005278172
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278173
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278170
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278174
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278168
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278166
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278171
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_005278167
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILGIRD 9
           ILG+RD
Sbjct: 382 ILGVRD 387
>XP_006715064
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ATFILGIRD 9
          +  +LGIRD
Sbjct: 85 SALLLGIRD 93
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.159    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 433,547
Number of extensions: 536
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package