Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           18    1482
NP_000170                                                              18    1482
NP_001025162                                                           18    1482
NP_073571                                                              18    1482
NP_001268422                                                           18    1482
NP_001268423                                                           18    1482
XP_006720300                                                           18    1482
XP_006720299                                                           18    1482
XP_006720298                                                           18    1482
XP_005264328                                                           18    1482
NP_061744                                                              17    3301
NP_114478                                                              17    3301
NP_001161337                                                           16    5631
NP_060085                                                              16    5631
NP_148936                                                              16    5631
NP_001245390                                                           16    5631
NP_006703                                                              16    5631
XP_006723482                                                           16    5631
XP_005259380                                                           16    5631
XP_005259381                                                           16    5631
XP_005259373                                                           16    5631
XP_006723481                                                           16    5631
XP_006723480                                                           16    5631
XP_005269985                                                           16    5631
XP_005249990                                                           16    5631
XP_005249989                                                           16    5631
NP_001005501                                                           16    5631
NP_115799                                                              16    5631
NP_005561                                                              16    7355
NP_954713                                                              16    7355
NP_005318                                                              15    9605
NP_653297                                                              15    9605
NP_001171634                                                           15    9605
NP_001244947                                                           15    9605
NP_758962                                                              15    9605
NP_001244946                                                           15    9605
NP_060830                                                              15    9605
NP_079040                                                              15    9605
NP_001164433                                                           15    9605
NP_001546                                                              15    9605
NP_001164432                                                           15    9605
NP_001162154                                                           15    9605
XP_006724819                                                           15    9605
XP_006724818                                                           15    9605
XP_005274615                                                           15    9605
XP_005273975                                                           15    9605
XP_006718567                                                           15    9605
XP_006718566                                                           15    9605
XP_006718565                                                           15    9605
XP_005263029                                                           15    9605
XP_006711224                                                           15    9605
XP_006711223                                                           15    9605
XP_006711222                                                           15    9605
XP_006711221                                                           15    9605
XP_006711220                                                           15    9605
NP_001032302                                                           15    9605
>NP_001268421
          Length = 1230

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATAHFLVLV 9
            ATAH LVLV
Sbjct: 1074 ATAHSLVLV 1082
>NP_000170
          Length = 1360

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATAHFLVLV 9
            ATAH LVLV
Sbjct: 1204 ATAHSLVLV 1212
>NP_001025162
          Length = 478

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HFLVLV
Sbjct: 288 TGHFLVLV 295
>NP_073571
          Length = 456

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HFLVLV
Sbjct: 288 TGHFLVLV 295
>NP_001268422
          Length = 1058

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ATAHFLVLV 9
           ATAH LVLV
Sbjct: 902 ATAHSLVLV 910
>NP_001268423
          Length = 1058

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ATAHFLVLV 9
           ATAH LVLV
Sbjct: 902 ATAHSLVLV 910
>XP_006720300
          Length = 320

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HFLVLV
Sbjct: 130 TGHFLVLV 137
>XP_006720299
          Length = 320

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HFLVLV
Sbjct: 130 TGHFLVLV 137
>XP_006720298
          Length = 447

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HFLVLV
Sbjct: 288 TGHFLVLV 295
>XP_005264328
          Length = 1261

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ATAHFLVLV 9
            ATAH LVLV
Sbjct: 1105 ATAHSLVLV 1113
>NP_061744
          Length = 932

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           ATAH LVL
Sbjct: 205 ATAHHLVL 212
>NP_114478
          Length = 828

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           ATAH LVL
Sbjct: 205 ATAHHLVL 212
>NP_001161337
          Length = 384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AHFLVL 8
           AHFLVL
Sbjct: 134 AHFLVL 139
>NP_060085
          Length = 385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AHFLVL 8
           AHFLVL
Sbjct: 134 AHFLVL 139
>NP_148936
          Length = 408

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           A AHFLV+
Sbjct: 119 AIAHFLVV 126
>NP_001245390
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           A AHFLV+
Sbjct: 233 AIAHFLVV 240
>NP_006703
          Length = 549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           A AHFLV+
Sbjct: 260 AIAHFLVV 267
>XP_006723482
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 220 TAHFLI 225
>XP_005259380
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 391 TAHFLI 396
>XP_005259381
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 391 TAHFLI 396
>XP_005259373
          Length = 664

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 489 TAHFLI 494
>XP_006723481
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 537 TAHFLI 542
>XP_006723480
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 573 TAHFLI 578
>XP_005269985
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AHFLVL 8
           AHFLVL
Sbjct: 134 AHFLVL 139
>XP_005249990
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           A AHFLV+
Sbjct: 226 AIAHFLVV 233
>XP_005249989
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           A AHFLV+
Sbjct: 226 AIAHFLVV 233
>NP_001005501
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TAHFLVL 8
           TAHF+V+
Sbjct: 241 TAHFIVV 247
>NP_115799
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TAHFLV 7
           TAHFL+
Sbjct: 453 TAHFLI 458
>NP_005561
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   ATAHFLVLV 9
           +T HF++ V
Sbjct: 477 STVHFIIFV 485
>NP_954713
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ATAHFLVLV 9
           A+AH +VL+
Sbjct: 135 ASAHLVVLI 143
>NP_005318
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ATAHFLVLV 9
          AT H +VLV
Sbjct: 48 ATGHTVVLV 56
>NP_653297
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HF++L+
Sbjct: 434 TKHFIILL 441
>NP_001171634
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ATAHFLVLV 9
          AT H +VLV
Sbjct: 48 ATGHTVVLV 56
>NP_001244947
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TAHFLVLV 9
          T H LVLV
Sbjct: 27 TLHLLVLV 34
>NP_758962
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TAHFLVLV 9
          T H LVLV
Sbjct: 27 TLHLLVLV 34
>NP_001244946
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TAHFLVLV 9
          T H LVLV
Sbjct: 27 TLHLLVLV 34
>NP_060830
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ATAHFLV 7
           ATAHF +
Sbjct: 240 ATAHFQI 246
>NP_079040
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HFLV++
Sbjct: 250 TNHFLVIL 257
>NP_001164433
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           + AHFL++
Sbjct: 821 SAAHFLII 828
>NP_001546
          Length = 1336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           + AHFL++
Sbjct: 830 SAAHFLII 837
>NP_001164432
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           + AHFL++
Sbjct: 835 SAAHFLII 842
>NP_001162154
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ATAHFLV 7
           ATAHF +
Sbjct: 108 ATAHFQI 114
>XP_006724819
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           + AHFL++
Sbjct: 830 SAAHFLII 837
>XP_006724818
          Length = 1304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ATAHFLVL 8
           + AHFL++
Sbjct: 830 SAAHFLII 837
>XP_005274615
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ATAHFLV 7
           ATAHF +
Sbjct: 240 ATAHFQI 246
>XP_005273975
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ATAHFLV 7
          AT HF+V
Sbjct: 66 ATEHFIV 72
>XP_006718567
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ATAHFLV 7
          AT HF+V
Sbjct: 66 ATEHFIV 72
>XP_006718566
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ATAHFLV 7
          AT HF+V
Sbjct: 66 ATEHFIV 72
>XP_006718565
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ATAHFLV 7
          AT HF+V
Sbjct: 66 ATEHFIV 72
>XP_005263029
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ATAHFLVLV 9
          AT H +VLV
Sbjct: 52 ATGHTVVLV 60
>XP_006711224
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HF++L+
Sbjct: 434 TKHFIILL 441
>XP_006711223
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HF++L+
Sbjct: 434 TKHFIILL 441
>XP_006711222
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HF++L+
Sbjct: 392 TKHFIILL 399
>XP_006711221
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HF++L+
Sbjct: 434 TKHFIILL 441
>XP_006711220
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TAHFLVLV 9
           T HF++L+
Sbjct: 434 TKHFIILL 441
>NP_001032302
          Length = 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ATAHFLV 7
          AT HF+V
Sbjct: 66 ATEHFIV 72
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.142    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 459,013
Number of extensions: 662
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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