Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              18    1135
NP_001243397                                                           18    1135
XP_005269721                                                           18    1135
NP_001795                                                              17    2528
NP_009225                                                              17    3301
NP_009230                                                              17    3301
NP_009228                                                              17    3301
NP_009229                                                              17    3301
NP_001931                                                              17    3301
NP_001007027                                                           17    3301
NP_001256                                                              17    3301
NP_009231                                                              17    3301
XP_006722104                                                           17    3301
XP_006722103                                                           17    3301
XP_006722102                                                           17    3301
XP_006722101                                                           17    3301
XP_006722100                                                           17    3301
XP_006722099                                                           17    3301
XP_006722098                                                           17    3301
XP_006722097                                                           17    3301
XP_006722096                                                           17    3301
XP_006722095                                                           17    3301
XP_006722094                                                           17    3301
XP_006722093                                                           17    3301
XP_006722092                                                           17    3301
NP_005550                                                              17    4312
NP_001002909                                                           16    5631
NP_064710                                                              16    5631
XP_006721846                                                           16    5631
XP_006721845                                                           16    5631
XP_006721844                                                           16    5631
XP_005255493                                                           16    5631
XP_006721128                                                           16    5631
XP_005255492                                                           16    5631
NP_065118                                                              16    7355
NP_001266278                                                           16    7355
NP_000483                                                              15    9605
NP_113584                                                              15    9605
NP_001243114                                                           15    9605
NP_001009555                                                           15    9605
NP_001122396                                                           15    9605
NP_689678                                                              15    9605
NP_060549                                                              15    9605
NP_001230278                                                           15    9605
NP_001243115                                                           15    9605
NP_001243117                                                           15    9605
NP_037478                                                              15    9605
NP_001243116                                                           15    9605
XP_005262029                                                           15    9605
XP_005262028                                                           15    9605
XP_005262026                                                           15    9605
XP_006724637                                                           15    9605
XP_005262025                                                           15    9605
XP_005262024                                                           15    9605
XP_005262023                                                           15    9605
XP_005262022                                                           15    9605
XP_005257989                                                           15    9605
XP_006721787                                                           15    9605
XP_005257987                                                           15    9605
XP_005257986                                                           15    9605
XP_005257985                                                           15    9605
XP_006721786                                                           15    9605
XP_005257984                                                           15    9605
XP_006715905                                                           15    9605
XP_006714165                                                           15    9605
XP_005262824                                                           15    9605
XP_006714164                                                           15    9605
XP_006714163                                                           15    9605
XP_006714162                                                           15    9605
XP_006714161                                                           15    9605
XP_006714160                                                           15    9605
XP_005262823                                                           15    9605
XP_005264455                                                           15    9605
NP_001122395                                                           15    9605
>NP_036462
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST KVNKK
Sbjct: 422 ASTLKVNKK 430
>NP_001243397
          Length = 1890

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST KVNKK
Sbjct: 422 ASTLKVNKK 430
>XP_005269721
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST KVNKK
Sbjct: 422 ASTLKVNKK 430
>NP_001795
          Length = 265

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           A  RKVNKK
Sbjct: 207 AKERKVNKK 215
>NP_009225
          Length = 1863

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1641 ASTERVNKR 1649
>NP_009230
          Length = 699

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 537 ASTERVNKR 545
>NP_009228
          Length = 1816

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1594 ASTERVNKR 1602
>NP_009229
          Length = 759

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 537 ASTERVNKR 545
>NP_001931
          Length = 1190

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ASTRKVNKK 9
          AST KVNK+
Sbjct: 62 ASTPKVNKQ 70
>NP_001007027
          Length = 1190

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ASTRKVNKK 9
          AST KVNK+
Sbjct: 62 ASTPKVNKQ 70
>NP_001256
          Length = 313

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           A  RK+NKK
Sbjct: 239 AKERKINKK 247
>NP_009231
          Length = 1884

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1662 ASTERVNKR 1670
>XP_006722104
          Length = 718

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 496 ASTERVNKR 504
>XP_006722103
          Length = 759

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 537 ASTERVNKR 545
>XP_006722102
          Length = 759

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 537 ASTERVNKR 545
>XP_006722101
          Length = 759

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 537 ASTERVNKR 545
>XP_006722100
          Length = 760

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           AST +VNK+
Sbjct: 538 ASTERVNKR 546
>XP_006722099
          Length = 1736

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1514 ASTERVNKR 1522
>XP_006722098
          Length = 1793

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1571 ASTERVNKR 1579
>XP_006722097
          Length = 1862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1640 ASTERVNKR 1648
>XP_006722096
          Length = 1862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1640 ASTERVNKR 1648
>XP_006722095
          Length = 1862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1640 ASTERVNKR 1648
>XP_006722094
          Length = 1863

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1641 ASTERVNKR 1649
>XP_006722093
          Length = 1863

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1641 ASTERVNKR 1649
>XP_006722092
          Length = 1863

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ASTRKVNKK 9
            AST +VNK+
Sbjct: 1641 ASTERVNKR 1649
>NP_005550
          Length = 3075

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ASTRKVNK 8
            AST+KVN+
Sbjct: 1638 ASTQKVNR 1645
>NP_001002909
          Length = 1502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    STRKVNKK 9
            +TRK NKK
Sbjct: 1153 ATRKPNKK 1160
>NP_064710
          Length = 1052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           + T+KVN+K
Sbjct: 132 SKTKKVNRK 140
>XP_006721846
          Length = 1424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    STRKVNKK 9
            +TRK NKK
Sbjct: 1075 ATRKPNKK 1082
>XP_006721845
          Length = 1424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    STRKVNKK 9
            +TRK NKK
Sbjct: 1075 ATRKPNKK 1082
>XP_006721844
          Length = 1424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    STRKVNKK 9
            +TRK NKK
Sbjct: 1075 ATRKPNKK 1082
>XP_005255493
          Length = 959

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           + T+KVN+K
Sbjct: 132 SKTKKVNRK 140
>XP_006721128
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           + T+KVN+K
Sbjct: 132 SKTKKVNRK 140
>XP_005255492
          Length = 1026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           + T+KVN+K
Sbjct: 132 SKTKKVNRK 140
>NP_065118
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TRKVNKK 9
          TRK NKK
Sbjct: 27 TRKKNKK 33
>NP_001266278
          Length = 250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TRKVNKK 9
          TRK NKK
Sbjct: 27 TRKKNKK 33
>NP_000483
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASTRKVN 7
           ASTRKV+
Sbjct: 789 ASTRKVS 795
>NP_113584
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3737 TRRANKK 3743
>NP_001243114
          Length = 162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ASTRKVNKK 9
          A TR++N K
Sbjct: 7  ADTRRLNSK 15
>NP_001009555
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 353 SATRRSNKK 361
>NP_001122396
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 317 SATRRSNKK 325
>NP_689678
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 317 SQARKVNKR 325
>NP_060549
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   STRKVNKK 9
           S++KVN+K
Sbjct: 406 SSKKVNEK 413
>NP_001230278
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 353 SATRRSNKK 361
>NP_001243115
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ASTRKVNKK 9
          A TR++N K
Sbjct: 7  ADTRRLNSK 15
>NP_001243117
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ASTRKVNKK 9
          A TR++N K
Sbjct: 7  ADTRRLNSK 15
>NP_037478
          Length = 162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ASTRKVNKK 9
          A TR++N K
Sbjct: 7  ADTRRLNSK 15
>NP_001243116
          Length = 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ASTRKVNKK 9
          A TR++N K
Sbjct: 7  ADTRRLNSK 15
>XP_005262029
          Length = 4240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3603 TRRANKK 3609
>XP_005262028
          Length = 4341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3704 TRRANKK 3710
>XP_005262026
          Length = 4359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3737 TRRANKK 3743
>XP_006724637
          Length = 4365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3728 TRRANKK 3734
>XP_005262025
          Length = 4373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3736 TRRANKK 3742
>XP_005262024
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3737 TRRANKK 3743
>XP_005262023
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3737 TRRANKK 3743
>XP_005262022
          Length = 4374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TRKVNKK 9
            TR+ NKK
Sbjct: 3737 TRRANKK 3743
>XP_005257989
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 319 SQARKVNKR 327
>XP_006721787
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 245 SQARKVNKR 253
>XP_005257987
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 245 SQARKVNKR 253
>XP_005257986
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 245 SQARKVNKR 253
>XP_005257985
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 245 SQARKVNKR 253
>XP_006721786
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 342 SQARKVNKR 350
>XP_005257984
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ASTRKVNKK 9
           +  RKVNK+
Sbjct: 345 SQARKVNKR 353
>XP_006715905
          Length = 1588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ASTRKVN 7
           ASTRKV+
Sbjct: 897 ASTRKVS 903
>XP_006714165
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 353 SATRRSNKK 361
>XP_005262824
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 353 SATRRSNKK 361
>XP_006714164
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 574 SATRRSNKK 582
>XP_006714163
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 574 SATRRSNKK 582
>XP_006714162
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 574 SATRRSNKK 582
>XP_006714161
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 583 SATRRSNKK 591
>XP_006714160
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 633 SATRRSNKK 641
>XP_005262823
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 633 SATRRSNKK 641
>XP_005264455
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   STRKVNKK 9
           S++KVN+K
Sbjct: 406 SSKKVNEK 413
>NP_001122395
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ASTRKVNKK 9
           ++TR+ NKK
Sbjct: 353 SATRRSNKK 361
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.105    0.244 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,409
Number of extensions: 553
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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