Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_665698                                                              17    4312
NP_001098983                                                           17    4312
XP_006713075                                                           17    4312
XP_005264984                                                           17    4312
XP_005264982                                                           17    4312
XP_005264980                                                           17    4312
XP_006713074                                                           17    4312
XP_005264979                                                           17    4312
XP_005264978                                                           17    4312
NP_000366                                                              16    5631
XP_005270198                                                           16    5631
XP_005270197                                                           16    5631
XP_005270196                                                           16    5631
XP_005270195                                                           16    5631
XP_006718023                                                           16    5631
XP_005270194                                                           16    5631
NP_036566                                                              16    7355
NP_001070                                                              16    7355
NP_997402                                                              16    7355
NP_001072982                                                           16    7355
NP_079524                                                              16    7355
NP_775840                                                              16    7355
NP_001275585                                                           16    7355
XP_006725425                                                           16    7355
XP_006725424                                                           16    7355
XP_006725423                                                           16    7355
XP_006725422                                                           16    7355
XP_006725421                                                           16    7355
XP_006725420                                                           16    7355
XP_006725419                                                           16    7355
XP_006722186                                                           16    7355
XP_006722185                                                           16    7355
XP_006722184                                                           16    7355
XP_006722183                                                           16    7355
XP_006722182                                                           16    7355
XP_006722181                                                           16    7355
XP_006722180                                                           16    7355
XP_005255340                                                           16    7355
XP_005255337                                                           16    7355
XP_005255336                                                           16    7355
XP_005255335                                                           16    7355
XP_005255334                                                           16    7355
XP_006715979                                                           16    7355
XP_005250306                                                           16    7355
XP_005248768                                                           16    7355
XP_006715522                                                           16    7355
XP_005248767                                                           16    7355
XP_006712792                                                           16    7355
XP_005264072                                                           16    7355
NP_001155973                                                           15    9605
NP_055903                                                              15    9605
NP_110404                                                              15    9605
XP_006723943                                                           15    9605
XP_006723942                                                           15    9605
>NP_665698
          Length = 1320

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 762 ASLASRIG 769
>NP_001098983
          Length = 1272

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 714 ASLASRIG 721
>XP_006713075
          Length = 1019

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 755 ASLASRIG 762
>XP_005264984
          Length = 1140

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 568 ASLASRIG 575
>XP_005264982
          Length = 1286

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 714 ASLASRIG 721
>XP_005264980
          Length = 1313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 755 ASLASRIG 762
>XP_006713074
          Length = 1318

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 755 ASLASRIG 762
>XP_005264979
          Length = 1322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 755 ASLASRIG 762
>XP_005264978
          Length = 1327

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASLASKVG 8
           ASLAS++G
Sbjct: 755 ASLASRIG 762
>NP_000366
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>XP_005270198
          Length = 139

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>XP_005270197
          Length = 223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>XP_005270196
          Length = 262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>XP_005270195
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>XP_006718023
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>XP_005270194
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASL SK+G
Sbjct: 104 ASLVSKIG 111
>NP_036566
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LASKVGG 9
           +ASK+GG
Sbjct: 129 VASKIGG 135
>NP_001070
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLASKVGG 9
           SLASKV G
Sbjct: 599 SLASKVEG 606
>NP_997402
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLASKVGG 9
           SLASKV G
Sbjct: 292 SLASKVEG 299
>NP_001072982
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>NP_079524
          Length = 1183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 380 LASKAGG 386
>NP_775840
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 228 ASLTTKYGG 236
>NP_001275585
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>XP_006725425
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 234 LASKAGG 240
>XP_006725424
          Length = 1078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 234 LASKAGG 240
>XP_006725423
          Length = 1078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 234 LASKAGG 240
>XP_006725422
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 331 LASKAGG 337
>XP_006725421
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 331 LASKAGG 337
>XP_006725420
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 290 LASKAGG 296
>XP_006725419
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 331 LASKAGG 337
>XP_006722186
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 234 LASKAGG 240
>XP_006722185
          Length = 1078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 234 LASKAGG 240
>XP_006722184
          Length = 1078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 234 LASKAGG 240
>XP_006722183
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 331 LASKAGG 337
>XP_006722182
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 331 LASKAGG 337
>XP_006722181
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 290 LASKAGG 296
>XP_006722180
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LASKVGG 9
           LASK GG
Sbjct: 331 LASKAGG 337
>XP_005255340
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>XP_005255337
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>XP_005255336
          Length = 1112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>XP_005255335
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>XP_005255334
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASLASKVGG 9
           ASL +K GG
Sbjct: 151 ASLTTKYGG 159
>XP_006715979
          Length = 1136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ASLASKVGG 9
          ASL +K GG
Sbjct: 17 ASLTTKYGG 25
>XP_005250306
          Length = 1170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ASLASKVGG 9
          ASL +K GG
Sbjct: 51 ASLTTKYGG 59
>XP_005248768
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LASKVGG 9
          +ASK+GG
Sbjct: 63 VASKIGG 69
>XP_006715522
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LASKVGG 9
           +ASK+GG
Sbjct: 129 VASKIGG 135
>XP_005248767
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LASKVGG 9
           +ASK+GG
Sbjct: 112 VASKIGG 118
>XP_006712792
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLASKVGG 9
           SLASKV G
Sbjct: 292 SLASKVEG 299
>XP_005264072
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLASKVGG 9
           SLASKV G
Sbjct: 593 SLASKVEG 600
>NP_001155973
          Length = 1833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASLASK G
Sbjct: 789 ASLASKGG 796
>NP_055903
          Length = 1723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ASLASKVG 8
           ASLASK G
Sbjct: 789 ASLASKGG 796
>NP_110404
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  ASLASKVGG 9
          A LAS VGG
Sbjct: 58 ALLASLVGG 66
>XP_006723943
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  ASLASKVGG 9
          A LAS VGG
Sbjct: 58 ALLASLVGG 66
>XP_006723942
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  ASLASKVGG 9
          A LAS VGG
Sbjct: 58 ALLASLVGG 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.118    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 270,259
Number of extensions: 360
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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