Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060496                                                              17    2528
XP_005274154                                                           17    2528
NP_005742                                                              17    3301
NP_671714                                                              17    3301
NP_112590                                                              17    3301
XP_006715890                                                           17    3301
XP_005250160                                                           17    3301
XP_005250159                                                           17    3301
NP_001136407                                                           17    3301
NP_055288                                                              17    4312
NP_001072                                                              17    4312
NP_036423                                                              16    5631
XP_006719768                                                           16    5631
NP_057726                                                              16    7355
NP_001094383                                                           16    7355
NP_056012                                                              16    7355
NP_065713                                                              16    7355
NP_001273193                                                           16    7355
NP_001273195                                                           16    7355
NP_036617                                                              16    7355
NP_001230056                                                           16    7355
NP_001273194                                                           16    7355
XP_005254495                                                           16    7355
XP_006720155                                                           16    7355
XP_006720154                                                           16    7355
XP_006720153                                                           16    7355
XP_006720152                                                           16    7355
XP_006720151                                                           16    7355
XP_006720150                                                           16    7355
XP_005267520                                                           16    7355
XP_006720149                                                           16    7355
XP_005267519                                                           16    7355
XP_006720148                                                           16    7355
XP_005249299                                                           16    7355
NP_008835                                                              15    9605
NP_001075109                                                           15    9605
NP_001274324                                                           15    9605
XP_006712547                                                           15    9605
>NP_060496
          Length = 963

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ASKLQVLLQ 9
           A+KLQ++LQ
Sbjct: 187 ANKLQIMLQ 195
>XP_005274154
          Length = 630

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ASKLQVLLQ 9
           A+KLQ++LQ
Sbjct: 187 ANKLQIMLQ 195
>NP_005742
          Length = 3907

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            ASKLQVL Q
Sbjct: 3523 ASKLQVLPQ 3531
>NP_671714
          Length = 3899

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            ASKLQVL Q
Sbjct: 3515 ASKLQVLPQ 3523
>NP_112590
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ASKLQVLLQ 9
          AS +QVLLQ
Sbjct: 5  ASNIQVLLQ 13
>XP_006715890
          Length = 3860

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            ASKLQVL Q
Sbjct: 3476 ASKLQVLPQ 3484
>XP_005250160
          Length = 3939

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            ASKLQVL Q
Sbjct: 3555 ASKLQVLPQ 3563
>XP_005250159
          Length = 3952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            ASKLQVL Q
Sbjct: 3568 ASKLQVLPQ 3576
>NP_001136407
          Length = 193

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ASKLQVLLQ 9
          AS +QVLLQ
Sbjct: 5  ASNIQVLLQ 13
>NP_055288
          Length = 313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ASKLQVLL 8
           ASKLQVL+
Sbjct: 104 ASKLQVLV 111
>NP_001072
          Length = 3623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    ASKLQVLL 8
            +SKLQVLL
Sbjct: 1363 SSKLQVLL 1370
>NP_036423
          Length = 2120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            AS+LQ LLQ
Sbjct: 1819 ASRLQELLQ 1827
>XP_006719768
          Length = 2120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ASKLQVLLQ 9
            AS+LQ LLQ
Sbjct: 1819 ASRLQELLQ 1827
>NP_057726
          Length = 3674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASKLQVLLQ 9
            A KLQ +LQ
Sbjct: 2472 AQKLQAMLQ 2480
>NP_001094383
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>NP_056012
          Length = 889

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>NP_065713
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLQVLLQ 9
           SKL +LLQ
Sbjct: 229 SKLHILLQ 236
>NP_001273193
          Length = 446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLQVLLQ 9
           SKL +LLQ
Sbjct: 232 SKLHILLQ 239
>NP_001273195
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLQVLLQ 9
           SKL +LLQ
Sbjct: 179 SKLHILLQ 186
>NP_036617
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SKLQVLLQ 9
          SK++VLLQ
Sbjct: 74 SKIRVLLQ 81
>NP_001230056
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SKLQVLLQ 9
          +KLQ++LQ
Sbjct: 42 NKLQIMLQ 49
>NP_001273194
          Length = 408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLQVLLQ 9
           SKL +LLQ
Sbjct: 229 SKLHILLQ 236
>XP_005254495
          Length = 3694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASKLQVLLQ 9
            A KLQ +LQ
Sbjct: 2492 AQKLQAMLQ 2500
>XP_006720155
          Length = 881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720154
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720153
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720152
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720151
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720150
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_005267520
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720149
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_005267519
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_006720148
          Length = 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SKLQVLLQ 9
           +KLQ++LQ
Sbjct: 109 NKLQIMLQ 116
>XP_005249299
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLQVLLQ 9
           SKL +LLQ
Sbjct: 229 SKLHILLQ 236
>NP_008835
          Length = 4128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SKLQVLLQ 9
            SKL++LLQ
Sbjct: 3047 SKLKLLLQ 3054
>NP_001075109
          Length = 4097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SKLQVLLQ 9
            SKL++LLQ
Sbjct: 3047 SKLKLLLQ 3054
>NP_001274324
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASKLQVLL 8
           ASK++VLL
Sbjct: 704 ASKVEVLL 711
>XP_006712547
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASKLQVLL 8
           ASK++VLL
Sbjct: 701 ASKVEVLL 708
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.128    0.284 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 288,983
Number of extensions: 604
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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