Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              21     175
XP_006714104                                                           21     175
XP_005265800                                                           21     175
XP_006714103                                                           21     175
XP_006714102                                                           21     175
XP_006715597                                                           17    2528
XP_005248809                                                           17    2528
NP_001695                                                              17    2528
NP_000866                                                              17    4312
XP_005254954                                                           17    4312
XP_005254953                                                           17    4312
XP_006720550                                                           17    4312
XP_006720549                                                           17    4312
NP_002244                                                              16    5631
NP_004775                                                              16    5631
NP_001693                                                              16    5631
XP_005251072                                                           16    5631
XP_006714479                                                           16    5631
NP_996920                                                              16    7355
NP_001990                                                              16    7355
NP_996919                                                              16    7355
NP_996921                                                              16    7355
NP_003196                                                              16    7355
NP_002010                                                              16    7355
NP_001153392                                                           16    7355
NP_001153503                                                           16    7355
NP_001153502                                                           16    7355
NP_057647                                                              16    7355
NP_115823                                                              16    7355
NP_001002034                                                           16    7355
XP_005261430                                                           16    7355
XP_006722988                                                           16    7355
XP_006720722                                                           16    7355
XP_006720721                                                           16    7355
XP_005254491                                                           16    7355
XP_005254490                                                           16    7355
XP_006710853                                                           16    7355
XP_006710852                                                           16    7355
XP_006710851                                                           16    7355
XP_006710850                                                           16    7355
XP_006710849                                                           16    7355
XP_005271124                                                           16    7355
XP_006710848                                                           16    7355
XP_006710847                                                           16    7355
XP_006710846                                                           16    7355
NP_001694                                                              16    7355
NP_001899                                                              15    9605
NP_680091                                                              15    9605
NP_680093                                                              15    9605
NP_680090                                                              15    9605
NP_680092                                                              15    9605
NP_000867                                                              15    9605
NP_003836                                                              15    9605
NP_001123885                                                           15    9605
NP_055417                                                              15    9605
NP_067058                                                              15    9605
NP_001245304                                                           15    9605
NP_001245303                                                           15    9605
NP_003787                                                              15    9605
NP_001239570                                                           15    9605
XP_005259420                                                           15    9605
XP_005259419                                                           15    9605
XP_006722890                                                           15    9605
XP_006722889                                                           15    9605
XP_006722888                                                           15    9605
XP_006722887                                                           15    9605
XP_006722886                                                           15    9605
XP_006716308                                                           15    9605
XP_006716307                                                           15    9605
NP_071414                                                              15    9605
>NP_006197
          Length = 1089

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ASFDSRQGF 9
           AS+DSRQGF
Sbjct: 170 ASYDSRQGF 178
>XP_006714104
          Length = 832

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ASFDSRQGF 9
           AS+DSRQGF
Sbjct: 195 ASYDSRQGF 203
>XP_005265800
          Length = 1089

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ASFDSRQGF 9
           AS+DSRQGF
Sbjct: 170 ASYDSRQGF 178
>XP_006714103
          Length = 1111

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ASFDSRQGF 9
           AS+DSRQGF
Sbjct: 192 ASYDSRQGF 200
>XP_006714102
          Length = 1114

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ASFDSRQGF 9
           AS+DSRQGF
Sbjct: 195 ASYDSRQGF 203
>XP_006715597
          Length = 1489

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A FDS QGF
Sbjct: 1100 AVFDSLQGF 1108
>XP_005248809
          Length = 1522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A FDS QGF
Sbjct: 1133 AVFDSLQGF 1141
>NP_001695
          Length = 1522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A FDS QGF
Sbjct: 1133 AVFDSLQGF 1141
>NP_000866
          Length = 1367

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            ASFD RQ +
Sbjct: 1338 ASFDERQPY 1346
>XP_005254954
          Length = 1246

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            ASFD RQ +
Sbjct: 1217 ASFDERQPY 1225
>XP_005254953
          Length = 1366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            ASFD RQ +
Sbjct: 1337 ASFDERQPY 1345
>XP_006720550
          Length = 1373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            ASFD RQ +
Sbjct: 1344 ASFDERQPY 1352
>XP_006720549
          Length = 1374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            ASFD RQ +
Sbjct: 1345 ASFDERQPY 1353
>NP_002244
          Length = 1356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SFDSRQGF 9
           S+DS++GF
Sbjct: 178 SWDSKKGF 185
>NP_004775
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           +FDS +GF
Sbjct: 800 TFDSHKGF 807
>NP_001693
          Length = 1584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A FDS +GF
Sbjct: 1170 AVFDSLEGF 1178
>XP_005251072
          Length = 1586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A FDS +GF
Sbjct: 1167 AVFDSLEGF 1175
>XP_006714479
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           +FDS +GF
Sbjct: 800 TFDSHKGF 807
>NP_996920
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SFDSRQGF 9
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_001990
          Length = 2912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FDSRQGF 9
            FD+RQ F
Sbjct: 2097 FDTRQSF 2103
>NP_996919
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SFDSRQGF 9
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_996921
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SFDSRQGF 9
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_003196
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SFDSRQGF 9
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_002010
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FDSRQGF 9
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153392
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FDSRQGF 9
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153503
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FDSRQGF 9
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153502
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FDSRQGF 9
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_057647
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SFDSRQGF 9
           S DSRQ F
Sbjct: 99  SVDSRQSF 106
>NP_115823
          Length = 2809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FDSRQGF 9
            FD+RQ F
Sbjct: 2010 FDTRQSF 2016
>NP_001002034
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SFDSRQG 8
          SF+SR+G
Sbjct: 54 SFESREG 60
>XP_005261430
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SFDSRQG 8
          SF+SR+G
Sbjct: 54 SFESREG 60
>XP_006722988
          Length = 2818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    FDSRQGF 9
            FD+RQ F
Sbjct: 2019 FDTRQSF 2025
>XP_006720722
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SFDSRQGF 9
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>XP_006720721
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SFDSRQGF 9
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>XP_005254491
          Length = 151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SFDSRQGF 9
           S DSRQ F
Sbjct: 99  SVDSRQSF 106
>XP_005254490
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  SFDSRQGF 9
          S DSRQ F
Sbjct: 80 SVDSRQSF 87
>XP_006710853
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1100 AVFNSAQGF 1108
>XP_006710852
          Length = 1497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1100 AVFNSAQGF 1108
>XP_006710851
          Length = 1511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1133 AVFNSAQGF 1141
>XP_006710850
          Length = 1530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1133 AVFNSAQGF 1141
>XP_006710849
          Length = 1530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1133 AVFNSAQGF 1141
>XP_005271124
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1155 AVFNSAQGF 1163
>XP_006710848
          Length = 1552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1155 AVFNSAQGF 1163
>XP_006710847
          Length = 1566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1188 AVFNSAQGF 1196
>XP_006710846
          Length = 1584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1188 AVFNSAQGF 1196
>NP_001694
          Length = 1585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A F+S QGF
Sbjct: 1188 AVFNSAQGF 1196
>NP_001899
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>NP_680091
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>NP_680093
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>NP_680090
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>NP_680092
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>NP_000867
          Length = 2491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   FDSRQGF 9
           FDS+ GF
Sbjct: 630 FDSQAGF 636
>NP_003836
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  SFDSRQGF 9
          SFD   GF
Sbjct: 84 SFDDEHGF 91
>NP_001123885
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ASFDSRQ 7
           ASF SRQ
Sbjct: 111 ASFQSRQ 117
>NP_055417
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ASFDSRQGF 9
            A+F + QGF
Sbjct: 1336 ATFQTTQGF 1344
>NP_067058
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>NP_001245304
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>NP_001245303
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>NP_003787
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ASFDSRQG 8
           A FD R+G
Sbjct: 429 AEFDDRRG 436
>NP_001239570
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ASFDSRQG 8
           A FD R+G
Sbjct: 411 AEFDDRRG 418
>XP_005259420
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ASFDSRQG 8
           A FD R+G
Sbjct: 429 AEFDDRRG 436
>XP_005259419
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ASFDSRQG 8
           A FD R+G
Sbjct: 411 AEFDDRRG 418
>XP_006722890
          Length = 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722889
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722888
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722887
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 637 SFNSAEGF 644
>XP_006722886
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SFDSRQGF 9
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006716308
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>XP_006716307
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ASFDSRQ 7
          ASFD+R+
Sbjct: 82 ASFDARE 88
>NP_071414
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   FDSRQG 8
           FD RQG
Sbjct: 358 FDGRQG 363
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 540,632
Number of extensions: 978
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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