Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1482
NP_444254                                                              18    1482
NP_444253                                                              18    1482
NP_444255                                                              18    1482
XP_005247551                                                           18    1482
XP_005247550                                                           18    1482
XP_006713712                                                           18    1482
XP_005247549                                                           18    1482
NP_443120                                                              17    4312
NP_001006608                                                           17    4312
NP_955372                                                              17    4312
NP_055649                                                              17    4312
XP_005275724                                                           17    4312
XP_005275722                                                           17    4312
XP_005275721                                                           17    4312
XP_006725345                                                           17    4312
XP_006725344                                                           17    4312
XP_005275719                                                           17    4312
XP_006725343                                                           17    4312
XP_006725342                                                           17    4312
XP_005275717                                                           17    4312
XP_005275716                                                           17    4312
XP_005257941                                                           17    4312
XP_005257940                                                           17    4312
XP_006722274                                                           17    4312
XP_006722273                                                           17    4312
XP_005257939                                                           17    4312
XP_006722272                                                           17    4312
XP_005257937                                                           17    4312
XP_005257936                                                           17    4312
XP_005257935                                                           17    4312
XP_006722271                                                           17    4312
NP_065961                                                              16    5631
NP_001158137                                                           16    5631
NP_001103444                                                           16    5631
NP_001159681                                                           16    5631
NP_001159680                                                           16    5631
NP_009217                                                              16    5631
XP_006716134                                                           16    5631
XP_005268428                                                           16    5631
XP_005268427                                                           16    5631
XP_005268426                                                           16    5631
XP_006714818                                                           16    5631
NP_997400                                                              15    9605
NP_008918                                                              15    9605
NP_057735                                                              15    9605
NP_001177342                                                           15    9605
NP_001177341                                                           15    9605
NP_001177340                                                           15    9605
NP_055677                                                              15    9605
NP_982288                                                              15    9605
XP_006725314                                                           15    9605
XP_006721426                                                           15    9605
XP_005272494                                                           15    9605
XP_005272493                                                           15    9605
XP_005272492                                                           15    9605
XP_006720230                                                           15    9605
XP_006720229                                                           15    9605
XP_005248564                                                           15    9605
XP_005246497                                                           15    9605
NP_005900                                                              15    9605
NP_001072988                                                           15    9605
NP_001243055                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1271 ASDIRSSSL 1279
>NP_444254
          Length = 1845

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1271 ASDIRSSSL 1279
>NP_444253
          Length = 1914

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1340 ASDIRSSSL 1348
>NP_444255
          Length = 1863

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1340 ASDIRSSSL 1348
>XP_005247551
          Length = 1855

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1281 ASDIRSSSL 1289
>XP_005247550
          Length = 1856

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1350 ASDIRSSSL 1358
>XP_006713712
          Length = 1923

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1350 ASDIRSSSL 1358
>XP_005247549
          Length = 1924

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ASDIQSSSL 9
            ASDI+SSSL
Sbjct: 1350 ASDIRSSSL 1358
>NP_443120
          Length = 947

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 274 DIQSSSL 280
>NP_001006608
          Length = 1700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>NP_955372
          Length = 1634

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>NP_055649
          Length = 1700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005275724
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005275722
          Length = 969

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005275721
          Length = 1018

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006725345
          Length = 1600

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006725344
          Length = 1606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 138 DIQSSSL 144
>XP_005275719
          Length = 1625

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006725343
          Length = 1635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006725342
          Length = 1651

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005275717
          Length = 1665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005275716
          Length = 1676

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005257941
          Length = 969

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005257940
          Length = 1018

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006722274
          Length = 1576

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006722273
          Length = 1600

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005257939
          Length = 1606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 138 DIQSSSL 144
>XP_006722272
          Length = 1635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005257937
          Length = 1651

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005257936
          Length = 1665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_005257935
          Length = 1676

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>XP_006722271
          Length = 1700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   DIQSSSL 9
           DIQSSSL
Sbjct: 232 DIQSSSL 238
>NP_065961
          Length = 1934

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASDIQSSSL 9
           +SD+QSS L
Sbjct: 675 SSDLQSSQL 683
>NP_001158137
          Length = 1950

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASDIQSSSL 9
           +SD+QSS L
Sbjct: 675 SSDLQSSQL 683
>NP_001103444
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 184 ASDFMSSSL 192
>NP_001159681
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 428 ASDFMSSSL 436
>NP_001159680
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 428 ASDFMSSSL 436
>NP_009217
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 184 ASDFMSSSL 192
>XP_006716134
          Length = 1847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ASDIQSSSL 9
           +SD+QSS L
Sbjct: 599 SSDLQSSQL 607
>XP_005268428
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 184 ASDFMSSSL 192
>XP_005268427
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 184 ASDFMSSSL 192
>XP_005268426
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 184 ASDFMSSSL 192
>XP_006714818
          Length = 1147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD  SSSL
Sbjct: 428 ASDFMSSSL 436
>NP_997400
          Length = 1691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SDIQSSSL 9
            SD++SSS+
Sbjct: 1271 SDVESSSV 1278
>NP_008918
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDIQSSSL 9
           SD+ SSSL
Sbjct: 214 SDLSSSSL 221
>NP_057735
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD+QS  L
Sbjct: 444 ASDLQSKHL 452
>NP_001177342
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDIQSSSL 9
           SD+ SSSL
Sbjct: 185 SDLSSSSL 192
>NP_001177341
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDIQSSSL 9
           SD+ SSSL
Sbjct: 185 SDLSSSSL 192
>NP_001177340
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDIQSSSL 9
           SD+ SSSL
Sbjct: 214 SDLSSSSL 221
>NP_055677
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDIQSSS 8
           +DIQSSS
Sbjct: 548 NDIQSSS 554
>NP_982288
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDIQSSS 8
           SDI+SSS
Sbjct: 341 SDIESSS 347
>XP_006725314
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDIQSSSL 9
           SD+ SSSL
Sbjct: 214 SDLSSSSL 221
>XP_006721426
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDIQSSSL 9
           SD+ SSSL
Sbjct: 214 SDLSSSSL 221
>XP_005272494
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SDIQSSSL 9
            SD++SSS+
Sbjct: 1271 SDVESSSV 1278
>XP_005272493
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SDIQSSSL 9
            SD++SSS+
Sbjct: 1271 SDVESSSV 1278
>XP_005272492
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SDIQSSSL 9
            SD++SSS+
Sbjct: 1271 SDVESSSV 1278
>XP_006720230
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD+QS  L
Sbjct: 163 ASDLQSKHL 171
>XP_006720229
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD+QS  L
Sbjct: 355 ASDLQSKHL 363
>XP_005248564
          Length = 2342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SDIQSSSL 9
            SD+Q SSL
Sbjct: 1566 SDMQDSSL 1573
>XP_005246497
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDIQSSS 8
           SDI+SSS
Sbjct: 157 SDIESSS 163
>NP_005900
          Length = 2468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SDIQSSSL 9
            SD+Q SSL
Sbjct: 1692 SDMQDSSL 1699
>NP_001072988
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ASDIQSSSL 9
           ASD+QS  L
Sbjct: 407 ASDLQSKHL 415
>NP_001243055
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDIQSSS 8
           SDI+SSS
Sbjct: 349 SDIESSS 355
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287    0.101    0.211 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 354,551
Number of extensions: 650
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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