Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005179                                                              18    1482
NP_003650                                                              17    4312
XP_006712964                                                           17    4312
NP_072096                                                              16    5631
XP_005250590                                                           16    5631
XP_006716151                                                           16    5631
XP_006716150                                                           16    5631
XP_006716149                                                           16    5631
XP_005250589                                                           16    5631
NP_620311                                                              16    7355
NP_001185748                                                           16    7355
NP_620310                                                              16    7355
NP_001185749                                                           16    7355
NP_055391                                                              16    7355
NP_001185747                                                           16    7355
NP_073746                                                              16    7355
NP_001139806                                                           16    7355
NP_001180267                                                           16    7355
XP_006723397                                                           16    7355
XP_005259220                                                           16    7355
XP_006723396                                                           16    7355
XP_006723395                                                           16    7355
XP_006723394                                                           16    7355
XP_006723393                                                           16    7355
XP_006723392                                                           16    7355
XP_006717872                                                           16    7355
XP_005269777                                                           16    7355
XP_005269776                                                           16    7355
XP_006717871                                                           16    7355
XP_005269775                                                           16    7355
XP_006715737                                                           16    7355
NP_078780                                                              15    9605
NP_000065                                                              15    9605
NP_110389                                                              15    9605
XP_005276344                                                           15    9605
XP_005249984                                                           15    9605
XP_005276056                                                           15    9605
NP_055853                                                              15    9605



>NP_005179
          Length = 906

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ASAATALPQ 9
           ASAATA PQ
Sbjct: 848 ASAATASPQ 856





>NP_003650
          Length = 658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ASAATALP 8
          ASAATA P
Sbjct: 64 ASAATAAP 71





>XP_006712964
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           ASAA ALP
Sbjct: 139 ASAAAALP 146





>NP_072096
          Length = 1035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASAATALP 8
           ++AATALP
Sbjct: 461 SAAATALP 468





>XP_005250590
          Length = 1034

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASAATALP 8
           ++AATALP
Sbjct: 461 SAAATALP 468





>XP_006716151
          Length = 1035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASAATALP 8
           ++AATALP
Sbjct: 461 SAAATALP 468





>XP_006716150
          Length = 1035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASAATALP 8
           ++AATALP
Sbjct: 461 SAAATALP 468





>XP_006716149
          Length = 1035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASAATALP 8
           ++AATALP
Sbjct: 461 SAAATALP 468





>XP_005250589
          Length = 1035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ASAATALP 8
           ++AATALP
Sbjct: 461 SAAATALP 468





>NP_620311
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>NP_001185748
          Length = 602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 545 AAAATAFP 552





>NP_620310
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>NP_001185749
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>NP_055391
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 529 AAAATAFP 536





>NP_001185747
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 529 AAAATAFP 536





>NP_073746
          Length = 1386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 933 SAATLLPE 940





>NP_001139806
          Length = 1562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAA A+PQ
Sbjct: 519 SAAMAMPQ 526





>NP_001180267
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   AATALPQ 9
           AATALP+
Sbjct: 262 AATALPK 268





>XP_006723397
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 874 SAATLLPE 881





>XP_005259220
          Length = 1386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 933 SAATLLPE 940





>XP_006723396
          Length = 1386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 933 SAATLLPE 940





>XP_006723395
          Length = 1387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 934 SAATLLPE 941





>XP_006723394
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 953 SAATLLPE 960





>XP_006723393
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 953 SAATLLPE 960





>XP_006723392
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAAT LP+
Sbjct: 953 SAATLLPE 960





>XP_006717872
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>XP_005269777
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>XP_005269776
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>XP_006717871
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>XP_005269775
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AATA P
Sbjct: 537 AAAATAFP 544





>XP_006715737
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SAATALPQ 9
           SAA A+PQ
Sbjct: 519 SAAMAMPQ 526





>NP_078780
          Length = 571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ASAATALP 8
          ASAA A+P
Sbjct: 60 ASAAPAMP 67





>NP_000065
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SAATALP 8
          SAAT LP
Sbjct: 12 SAATGLP 18





>NP_110389
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ASAATALP 8
           A+AAT LP
Sbjct: 428 AAAATLLP 435





>XP_005276344
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AATALP 8
           AATALP
Sbjct: 201 AATALP 206





>XP_005249984
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AATALP 8
           AATALP
Sbjct: 201 AATALP 206





>XP_005276056
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AATALP 8
           AATALP
Sbjct: 201 AATALP 206





>NP_055853
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ASAATALP 8
            ASAA A+P
Sbjct: 1157 ASAAVAVP 1164





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.101    0.249 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,779
Number of extensions: 385
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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