Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_058642                                                              17    3301
NP_001005407                                                           17    4312
NP_066921                                                              17    4312
NP_001243257                                                           17    4312
NP_938406                                                              17    4312
NP_938191                                                              17    4312
NP_061496                                                              17    4312
NP_938197                                                              17    4312
NP_938200                                                              17    4312
NP_001243262                                                           17    4312
NP_938194                                                              17    4312
NP_001243289                                                           17    4312
NP_938202                                                              17    4312
NP_938199                                                              17    4312
NP_938192                                                              17    4312
NP_001243255                                                           17    4312
NP_938193                                                              17    4312
NP_001243290                                                           17    4312
NP_001243258                                                           17    4312
NP_001243254                                                           17    4312
NP_938201                                                              17    4312
NP_001243263                                                           17    4312
NP_001243261                                                           17    4312
NP_001243259                                                           17    4312
NP_938190                                                              17    4312
NP_938196                                                              17    4312
NP_938198                                                              17    4312
NP_001243256                                                           17    4312
NP_001243260                                                           17    4312
NP_001243288                                                           17    4312
NP_001243253                                                           17    4312
XP_006722224                                                           17    4312
XP_006722223                                                           17    4312
XP_006721032                                                           17    4312
XP_006721031                                                           17    4312
XP_006721030                                                           17    4312
XP_006721029                                                           17    4312
XP_006721028                                                           17    4312
XP_006721027                                                           17    4312
XP_005255709                                                           17    4312
XP_006721026                                                           17    4312
NP_000258                                                              16    5631
NP_001035957                                                           16    5631
XP_006721991                                                           16    5631
XP_006721990                                                           16    5631
XP_006721989                                                           16    5631
XP_005258041                                                           16    5631
XP_006721988                                                           16    5631
XP_006721987                                                           16    5631
XP_006721986                                                           16    5631
XP_005258040                                                           16    5631
XP_006721985                                                           16    5631
NP_742152                                                              15    9605
NP_001073866                                                           15    9605
NP_071903                                                              15    9605
XP_005249615                                                           15    9605
XP_005249612                                                           15    9605
>NP_058642
          Length = 299

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARVLVTLIL 9
           A VLVTLIL
Sbjct: 241 AAVLVTLIL 249
>NP_001005407
          Length = 2347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>NP_066921
          Length = 2353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>NP_001243257
          Length = 2259

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938406
          Length = 2343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938191
          Length = 2366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_061496
          Length = 2377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938197
          Length = 2306

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938200
          Length = 2266

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243262
          Length = 2205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938194
          Length = 2321

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243289
          Length = 2248

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938202
          Length = 2243

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938199
          Length = 2332

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938192
          Length = 2273

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243255
          Length = 2287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938193
          Length = 2298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243290
          Length = 2246

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243258
          Length = 2250

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243254
          Length = 2291

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938201
          Length = 2250

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243263
          Length = 2194

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243261
          Length = 2227

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243259
          Length = 2239

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938190
          Length = 2171

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938196
          Length = 2261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_938198
          Length = 2284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243256
          Length = 2277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243260
          Length = 2232

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243288
          Length = 2257

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>NP_001243253
          Length = 2314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>XP_006722224
          Length = 2244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>XP_006722223
          Length = 2268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 198 RILVTLLL 205
>XP_006721032
          Length = 1566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_006721031
          Length = 1612

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_006721030
          Length = 1618

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_006721029
          Length = 1820

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_006721028
          Length = 2336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_006721027
          Length = 2342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_005255709
          Length = 2347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>XP_006721026
          Length = 2358

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RVLVTLIL 9
           R+LVTL+L
Sbjct: 217 RILVTLLL 224
>NP_000258
          Length = 2818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1240 ARVLVTL 1246
>NP_001035957
          Length = 2839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1240 ARVLVTL 1246
>XP_006721991
          Length = 1632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1250 ARVLVTL 1256
>XP_006721990
          Length = 2823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1250 ARVLVTL 1256
>XP_006721989
          Length = 2823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1250 ARVLVTL 1256
>XP_005258041
          Length = 2836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1240 ARVLVTL 1246
>XP_006721988
          Length = 2846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1250 ARVLVTL 1256
>XP_006721987
          Length = 2849

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1250 ARVLVTL 1256
>XP_006721986
          Length = 2854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1237 ARVLVTL 1243
>XP_005258040
          Length = 2857

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1240 ARVLVTL 1246
>XP_006721985
          Length = 2867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ARVLVTL 7
            ARVLVTL
Sbjct: 1250 ARVLVTL 1256
>NP_742152
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLVTLIL 9
          VLVTL+L
Sbjct: 8  VLVTLVL 14
>NP_001073866
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ARVLVTLIL 9
           A++LV+L+L
Sbjct: 721 AQILVSLVL 729
>NP_071903
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARVLVTLIL 9
           AR+L TL++
Sbjct: 145 ARILETLVM 153
>XP_005249615
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARVLVTLIL 9
           AR+L TL++
Sbjct: 145 ARILETLVM 153
>XP_005249612
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARVLVTLIL 9
           AR+L TL++
Sbjct: 145 ARILETLVM 153
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.348    0.157    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 252,557
Number of extensions: 273
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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