Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              18    1482
NP_001120972                                                           18    1482
XP_006716054                                                           18    1482
XP_006716053                                                           18    1482
XP_006716052                                                           18    1482
XP_006716051                                                           18    1482
NP_570843                                                              17    4312
NP_001128529                                                           17    4312
NP_001137357                                                           16    5631
NP_001137358                                                           16    5631
NP_001231921                                                           16    5631
NP_001231919                                                           16    5631
NP_002471                                                              16    5631
NP_851999                                                              16    5631
NP_001185461                                                           16    5631
NP_001185462                                                           16    5631
XP_005268948                                                           16    5631
XP_005268946                                                           16    5631
XP_005268944                                                           16    5631
XP_005268945                                                           16    5631
XP_005268943                                                           16    5631
XP_005268942                                                           16    5631
XP_006716659                                                           16    5631
XP_005251053                                                           16    5631
XP_005251052                                                           16    5631
XP_006716658                                                           16    5631
XP_005251051                                                           16    5631
XP_005251050                                                           16    5631
XP_006716657                                                           16    5631
NP_060472                                                              16    5631
NP_001244119                                                           16    7355
NP_742017                                                              16    7355
XP_006716259                                                           16    7355
XP_006716258                                                           16    7355
XP_005250789                                                           16    7355
XP_005250788                                                           16    7355
XP_005250787                                                           16    7355
XP_005250786                                                           16    7355
XP_006716257                                                           16    7355
XP_005250785                                                           16    7355
XP_005250784                                                           16    7355
XP_005250783                                                           16    7355
NP_009045                                                              15    9605
>NP_000236
          Length = 1390

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           ARSVS TTE
Sbjct: 986 ARSVSPTTE 994
>NP_001120972
          Length = 1408

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARSVSSTTE 9
            ARSVS TTE
Sbjct: 1004 ARSVSPTTE 1012
>XP_006716054
          Length = 960

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           ARSVS TTE
Sbjct: 556 ARSVSPTTE 564
>XP_006716053
          Length = 960

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           ARSVS TTE
Sbjct: 556 ARSVSPTTE 564
>XP_006716052
          Length = 1409

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARSVSSTTE 9
            ARSVS TTE
Sbjct: 1005 ARSVSPTTE 1013
>XP_006716051
          Length = 1427

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARSVSSTTE 9
            ARSVS TTE
Sbjct: 1023 ARSVSPTTE 1031
>NP_570843
          Length = 581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SVSSTTE 9
           SVSSTTE
Sbjct: 501 SVSSTTE 507
>NP_001128529
          Length = 587

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SVSSTTE 9
           SVSSTTE
Sbjct: 507 SVSSTTE 513
>NP_001137357
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>NP_001137358
          Length = 943

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 566 AGTVSSTTE 574
>NP_001231921
          Length = 974

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 597 AGTVSSTTE 605
>NP_001231919
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>NP_002471
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>NP_851999
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 189 ARVVSSTSE 197
>NP_001185461
          Length = 874

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 197 ARVVSSTSE 205
>NP_001185462
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 196 ARVVSSTSE 204
>XP_005268948
          Length = 990

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 597 AGTVSSTTE 605
>XP_005268946
          Length = 999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>XP_005268944
          Length = 1005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>XP_005268945
          Length = 1005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>XP_005268943
          Length = 1034

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 641 AGTVSSTTE 649
>XP_005268942
          Length = 1046

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 653 AGTVSSTTE 661
>XP_006716659
          Length = 653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 197 ARVVSSTSE 205
>XP_005251053
          Length = 826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 127 ARVVSSTSE 135
>XP_005251052
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 129 ARVVSSTSE 137
>XP_006716658
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 197 ARVVSSTSE 205
>XP_005251051
          Length = 888

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 189 ARVVSSTSE 197
>XP_005251050
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 196 ARVVSSTSE 204
>XP_006716657
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 197 ARVVSSTSE 205
>NP_060472
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           AR VSST+E
Sbjct: 196 ARVVSSTSE 204
>NP_001244119
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>NP_742017
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_006716259
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_006716258
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_005250789
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_005250788
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_005250787
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_005250786
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_006716257
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_005250785
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ARSVSSTTE 9
           A +VSSTTE
Sbjct: 897 AFNVSSTTE 905
>XP_005250784
          Length = 1190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ARSVSSTTE 9
            A +VSSTTE
Sbjct: 1103 AFNVSSTTE 1111
>XP_005250783
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ARSVSSTTE 9
            A +VSSTTE
Sbjct: 1162 AFNVSSTTE 1170
>NP_009045
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ARSVSSTT 8
           ++SVSSTT
Sbjct: 761 SQSVSSTT 768
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.279   0.0881    0.184 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 234,552
Number of extensions: 435
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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