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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718908                                                           19     869
XP_005271621                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
NP_056289                                                              17    2528
NP_001231892                                                           17    4312
NP_001104488                                                           17    4312
NP_660093                                                              17    4312
NP_892009                                                              17    4312
XP_006718429                                                           17    4312
XP_006718428                                                           17    4312
XP_006718427                                                           17    4312
XP_006711491                                                           16    7355
NP_060648                                                              16    7355
NP_079390                                                              15    9605
NP_001158058                                                           15    9605
XP_005254929                                                           15    9605
XP_006719673                                                           15    9605
XP_005269218                                                           15    9605
XP_005269217                                                           15    9605
XP_006719672                                                           15    9605
XP_005269215                                                           15    9605
XP_006711681                                                           15    9605
XP_006711680                                                           15    9605
XP_005245637                                                           15    9605
NP_001077088                                                           15    9605
NP_000817                                                              15    9605
NP_001077089                                                           15    9605

>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 2578 ARRSRITKN 2586



>XP_006718908
          Length = 1708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 1230 ARRSRITKN 1238



>XP_005271621
          Length = 2708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 2230 ARRSRITKN 2238



>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 2572 ARRSRITKN 2580



>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 2578 ARRSRITKN 2586



>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 2578 ARRSRITKN 2586



>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARRIRITKN 9
            ARR RITKN
Sbjct: 2578 ARRSRITKN 2586



>NP_056289
          Length = 626

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RRIRITKN 9
           R IRITKN
Sbjct: 528 RAIRITKN 535



>NP_001231892
          Length = 2488

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 744 ARRLRTVKN 752



>NP_001104488
          Length = 2365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 657 ARRLRTVKN 665



>NP_660093
          Length = 2429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 721 ARRLRTVKN 729



>NP_892009
          Length = 2432

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 721 ARRLRTVKN 729



>XP_006718429
          Length = 2416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 672 ARRLRTVKN 680



>XP_006718428
          Length = 2455

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 744 ARRLRTVKN 752



>XP_006718427
          Length = 2465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARRIRITKN 9
           ARR+R  KN
Sbjct: 721 ARRLRTVKN 729



>XP_006711491
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ARRIRITKN 9
          ARR  I+KN
Sbjct: 22 ARRTEISKN 30



>NP_060648
          Length = 285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ARRIRITKN 9
          ARR  I+KN
Sbjct: 8  ARRTEISKN 16



>NP_079390
          Length = 2479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ARRIRITKN 9
            A ++RI KN
Sbjct: 2220 AEKLRIAKN 2228



>NP_001158058
          Length = 3708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RRIRITKN 9
           R IR+TK+
Sbjct: 220 RHIRVTKD 227



>XP_005254929
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARRIRITKN 9
           ARRIR+ ++
Sbjct: 724 ARRIRVVED 732



>XP_006719673
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ARRIRITKN 9
            A ++RI KN
Sbjct: 1738 AEKLRIAKN 1746



>XP_005269218
          Length = 2009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ARRIRITKN 9
            A ++RI KN
Sbjct: 1750 AEKLRIAKN 1758



>XP_005269217
          Length = 2353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ARRIRITKN 9
            A ++RI KN
Sbjct: 2251 AEKLRIAKN 2259



>XP_006719672
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ARRIRITKN 9
            A ++RI KN
Sbjct: 2251 AEKLRIAKN 2259



>XP_005269215
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ARRIRITKN 9
            A ++RI KN
Sbjct: 2251 AEKLRIAKN 2259



>XP_006711681
          Length = 3448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RRIRITKN 9
           R IR+TK+
Sbjct: 220 RHIRVTKD 227



>XP_006711680
          Length = 3617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RRIRITKN 9
           R IR+TK+
Sbjct: 220 RHIRVTKD 227



>XP_005245637
          Length = 3683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RRIRITKN 9
           R IR+TK+
Sbjct: 220 RHIRVTKD 227



>NP_001077088
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ARRIRITKN 9
           A+R+++ KN
Sbjct: 843 AKRMKVAKN 851



>NP_000817
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ARRIRITKN 9
           A+R+++ KN
Sbjct: 843 AKRMKVAKN 851



>NP_001077089
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ARRIRITKN 9
           A+R+++ KN
Sbjct: 796 AKRMKVAKN 804



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.138    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,752
Number of extensions: 546
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)