Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     299
XP_005265800                                                           20     299
XP_006714103                                                           20     299
XP_006714102                                                           20     299
NP_065681                                                              18    1135
NP_066124                                                              18    1135
XP_006717999                                                           18    1135
NP_000213                                                              17    2528
NP_001087241                                                           17    2528
XP_006721172                                                           17    2528
XP_005265799                                                           17    2528
XP_005265798                                                           17    2528
XP_005265797                                                           17    2528
NP_005202                                                              17    3301
NP_055140                                                              17    3301
NP_001275634                                                           17    3301
NP_001098707                                                           17    3301
NP_001263400                                                           17    3301
NP_065174                                                              17    3301
NP_001018080                                                           17    3301
NP_116243                                                              17    3301
XP_005258110                                                           17    3301
XP_005258108                                                           17    3301
XP_005258106                                                           17    3301
XP_005258105                                                           17    3301
XP_005258104                                                           17    3301
NP_002011                                                              16    5631
NP_891555                                                              16    5631
NP_002244                                                              16    5631
NP_002010                                                              16    5631
NP_056505                                                              16    5631
NP_001230242                                                           16    5631
XP_006712484                                                           16    5631
XP_006712483                                                           16    5631
XP_005246521                                                           16    5631
NP_001010938                                                           16    7355
NP_005772                                                              16    7355
NP_653267                                                              16    7355
XP_006713531                                                           16    7355
XP_005269331                                                           16    7355
XP_005269330                                                           16    7355
XP_005269329                                                           16    7355
XP_005269328                                                           16    7355
XP_005269327                                                           16    7355
XP_006713530                                                           16    7355
XP_006713529                                                           16    7355
XP_005269326                                                           16    7355
XP_006713528                                                           16    7355
XP_006713527                                                           16    7355
XP_005269325                                                           16    7355
XP_006713526                                                           16    7355
XP_006713525                                                           16    7355
XP_006713524                                                           16    7355
XP_006713523                                                           16    7355
NP_003322                                                              15    9605
NP_689837                                                              15    9605
NP_776194                                                              15    9605
NP_001229306                                                           15    9605
NP_001180262                                                           15    9605
NP_001191375                                                           15    9605
NP_060817                                                              15    9605
NP_009005                                                              15    9605
XP_005271971                                                           15    9605
NP_001191376                                                           15    9605
>NP_006197
          Length = 1089

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARN+LLAQG
Sbjct: 821 ARNVLLAQG 829
>XP_005265800
          Length = 1089

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARN+LLAQG
Sbjct: 821 ARNVLLAQG 829
>XP_006714103
          Length = 1111

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARN+LLAQG
Sbjct: 843 ARNVLLAQG 851
>XP_006714102
          Length = 1114

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARN+LLAQG
Sbjct: 846 ARNVLLAQG 854
>NP_065681
          Length = 1072

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARNIL+A+G
Sbjct: 877 ARNILVAEG 885
>NP_066124
          Length = 1114

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARNIL+A+G
Sbjct: 877 ARNILVAEG 885
>XP_006717999
          Length = 1207

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   ARNILLAQG 9
           ARNIL+A+G
Sbjct: 970 ARNILVAEG 978
>NP_000213
          Length = 976

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARNILL  G
Sbjct: 795 ARNILLTHG 803
>NP_001087241
          Length = 972

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARNILL  G
Sbjct: 791 ARNILLTHG 799
>XP_006721172
          Length = 139

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  RNILLAQG 9
          RN LLAQG
Sbjct: 46 RNCLLAQG 53
>XP_005265799
          Length = 973

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARNILL  G
Sbjct: 792 ARNILLTHG 800
>XP_005265798
          Length = 976

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARNILL  G
Sbjct: 795 ARNILLTHG 803
>XP_005265797
          Length = 977

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARNILL  G
Sbjct: 796 ARNILLTHG 804
>NP_005202
          Length = 972

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARN+LL  G
Sbjct: 781 ARNVLLTNG 789
>NP_055140
          Length = 474

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 142 ARNVLLSAG 150
>NP_001275634
          Length = 972

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARNILLAQG 9
           ARN+LL  G
Sbjct: 781 ARNVLLTNG 789
>NP_001098707
          Length = 527

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 195 ARNVLLSAG 203
>NP_001263400
          Length = 474

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 142 ARNVLLSAG 150
>NP_065174
          Length = 489

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 144 ARNVLLSAG 152
>NP_001018080
          Length = 489

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 144 ARNVLLSAG 152
>NP_116243
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 143 ARNVLLSAG 151
>XP_005258110
          Length = 262

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 143 ARNVLLSAG 151
>XP_005258108
          Length = 431

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 102 ARNVLLSAG 110
>XP_005258106
          Length = 471

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 143 ARNVLLSAG 151
>XP_005258105
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 143 ARNVLLSAG 151
>XP_005258104
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           ARN+LL+ G
Sbjct: 143 ARNVLLSAG 151
>NP_002011
          Length = 1298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ARNILLAQ 8
            ARNILL++
Sbjct: 1040 ARNILLSE 1047
>NP_891555
          Length = 1363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ARNILLAQ 8
            ARNILL++
Sbjct: 1040 ARNILLSE 1047
>NP_002244
          Length = 1356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ARNILLAQ 8
            ARNILL++
Sbjct: 1031 ARNILLSE 1038
>NP_002010
          Length = 1338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ARNILLAQ 8
            ARNILL++
Sbjct: 1025 ARNILLSE 1032
>NP_056505
          Length = 1315

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RNILLAQG 9
           +NILLA+G
Sbjct: 129 QNILLAKG 136
>NP_001230242
          Length = 1294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RNILLAQG 9
           +NILLA+G
Sbjct: 129 QNILLAKG 136
>XP_006712484
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RNILLAQG 9
           +NILLA+G
Sbjct: 129 QNILLAKG 136
>XP_006712483
          Length = 1306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RNILLAQG 9
           +NILLA+G
Sbjct: 129 QNILLAKG 136
>XP_005246521
          Length = 1315

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RNILLAQG 9
           +NILLA+G
Sbjct: 129 QNILLAKG 136
>NP_001010938
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 318 ARNLLLA 324
>NP_005772
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 255 ARNLLLA 261
>NP_653267
          Length = 4753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RNILLAQG 9
            RNI+ AQG
Sbjct: 3817 RNIVRAQG 3824
>XP_006713531
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>XP_005269331
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ARNILLA 7
          ARN+LLA
Sbjct: 16 ARNLLLA 22
>XP_005269330
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 179 ARNLLLA 185
>XP_005269329
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 287 ARNLLLA 293
>XP_005269328
          Length = 1055

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 255 ARNLLLA 261
>XP_005269327
          Length = 1055

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 255 ARNLLLA 261
>XP_006713530
          Length = 1063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 263 ARNLLLA 269
>XP_006713529
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>XP_005269326
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 287 ARNLLLA 293
>XP_006713528
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>XP_006713527
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>XP_005269325
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 318 ARNLLLA 324
>XP_006713526
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>XP_006713525
          Length = 1119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 319 ARNLLLA 325
>XP_006713524
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>XP_006713523
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ARNILLA 7
           ARN+LLA
Sbjct: 333 ARNLLLA 339
>NP_003322
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RNILLAQ 8
           RNILLA+
Sbjct: 738 RNILLAR 744
>NP_689837
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILLAQG 9
           N+LL QG
Sbjct: 111 NVLLVQG 117
>NP_776194
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RNILLAQG 9
           RNI LA+G
Sbjct: 299 RNISLAKG 306
>NP_001229306
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILLAQG 9
           N+LL QG
Sbjct: 111 NVLLVQG 117
>NP_001180262
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           A+N+LL+ G
Sbjct: 143 AQNVLLSAG 151
>NP_001191375
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLAQG 9
           N+LLA+G
Sbjct: 131 NLLLAEG 137
>NP_060817
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLAQG 9
           N+LLA+G
Sbjct: 131 NLLLAEG 137
>NP_009005
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARNILLAQG 9
           A+N+LL+ G
Sbjct: 143 AQNVLLSAG 151
>XP_005271971
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NILLAQG 9
           N+LL QG
Sbjct: 111 NVLLVQG 117
>NP_001191376
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLAQG 9
           N+LLA+G
Sbjct: 131 NLLLAEG 137
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.139    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 342,755
Number of extensions: 494
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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