Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277223                                                           19     869
XP_005269496                                                           19     869
XP_005269494                                                           19     869
XP_006717651                                                           19     869
XP_006717650                                                           19     869
XP_005269488                                                           19     869
XP_006717647                                                           19     869
XP_006717646                                                           19     869
XP_005269482                                                           19     869
XP_006717643                                                           19     869
XP_005269481                                                           19     869
XP_006717641                                                           19     869
XP_006717640                                                           19     869
XP_006717639                                                           19     869
XP_006717638                                                           19     869
XP_006717636                                                           19     869
XP_006717635                                                           19     869
XP_006717634                                                           19     869
XP_006717633                                                           19     869
XP_006717632                                                           19     869
XP_006717631                                                           19     869
XP_005269471                                                           19     869
XP_006717630                                                           19     869
XP_006717629                                                           19     869
XP_005269469                                                           19     869
XP_005269468                                                           19     869
XP_006717628                                                           19     869
XP_006717627                                                           19     869
XP_006717626                                                           19     869
XP_006717624                                                           19     869
XP_005269463                                                           19     869
XP_005269461                                                           19     869
XP_006717623                                                           19     869
XP_005269462                                                           19     869
NP_059119                                                              17    3301
XP_005263119                                                           17    3301
NP_003030                                                              16    5631
NP_004332                                                              16    5631
NP_001494                                                              16    5631
NP_001003760                                                           16    5631
XP_005257123                                                           16    5631
XP_005249164                                                           16    5631
XP_005249075                                                           16    5631
XP_005264615                                                           16    5631
XP_006712164                                                           16    5631
XP_005264614                                                           16    5631
XP_005264613                                                           16    5631
XP_005264612                                                           16    5631
XP_006710899                                                           16    5631
XP_005263548                                                           16    5631
NP_004713                                                              16    7355
NP_036425                                                              16    7355
XP_005259447                                                           16    7355
XP_005259445                                                           16    7355
XP_005259444                                                           16    7355
XP_005259443                                                           16    7355
XP_005250748                                                           16    7355
XP_005250747                                                           16    7355
XP_006716238                                                           16    7355
XP_005250746                                                           16    7355
XP_006711959                                                           16    7355
XP_005264764                                                           16    7355
NP_001923                                                              15    9605
NP_001002264                                                           15    9605
NP_150280                                                              15    9605
NP_001158238                                                           15    9605
NP_001348                                                              15    9605
NP_008816                                                              15    9605
XP_006721980                                                           15    9605
XP_006721978                                                           15    9605
XP_005256014                                                           15    9605
XP_006719959                                                           15    9605
XP_005266654                                                           15    9605
XP_005266653                                                           15    9605
>NP_001277223
          Length = 1266

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1161 ARRGGSQLS 1169
>XP_005269496
          Length = 790

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARMGGSQLS 9
           AR GGSQLS
Sbjct: 641 ARRGGSQLS 649
>XP_005269494
          Length = 818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARMGGSQLS 9
           AR GGSQLS
Sbjct: 669 ARRGGSQLS 677
>XP_006717651
          Length = 1185

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1036 ARRGGSQLS 1044
>XP_006717650
          Length = 1192

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1043 ARRGGSQLS 1051
>XP_005269488
          Length = 1201

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1052 ARRGGSQLS 1060
>XP_006717647
          Length = 1224

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1075 ARRGGSQLS 1083
>XP_006717646
          Length = 1233

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1084 ARRGGSQLS 1092
>XP_005269482
          Length = 1315

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1166 ARRGGSQLS 1174
>XP_006717643
          Length = 1324

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1175 ARRGGSQLS 1183
>XP_005269481
          Length = 1324

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1175 ARRGGSQLS 1183
>XP_006717641
          Length = 1356

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1207 ARRGGSQLS 1215
>XP_006717640
          Length = 1424

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1275 ARRGGSQLS 1283
>XP_006717639
          Length = 1472

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1323 ARRGGSQLS 1331
>XP_006717638
          Length = 1511

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1362 ARRGGSQLS 1370
>XP_006717636
          Length = 1539

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1390 ARRGGSQLS 1398
>XP_006717635
          Length = 1539

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1390 ARRGGSQLS 1398
>XP_006717634
          Length = 1549

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1400 ARRGGSQLS 1408
>XP_006717633
          Length = 1551

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1446 ARRGGSQLS 1454
>XP_006717632
          Length = 1551

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1402 ARRGGSQLS 1410
>XP_006717631
          Length = 1554

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1405 ARRGGSQLS 1413
>XP_005269471
          Length = 1554

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1405 ARRGGSQLS 1413
>XP_006717630
          Length = 1561

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1412 ARRGGSQLS 1420
>XP_006717629
          Length = 1563

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1414 ARRGGSQLS 1422
>XP_005269469
          Length = 1563

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1414 ARRGGSQLS 1422
>XP_005269468
          Length = 1563

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1414 ARRGGSQLS 1422
>XP_006717628
          Length = 1570

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1421 ARRGGSQLS 1429
>XP_006717627
          Length = 1573

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1424 ARRGGSQLS 1432
>XP_006717626
          Length = 1574

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1425 ARRGGSQLS 1433
>XP_006717624
          Length = 1585

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1436 ARRGGSQLS 1444
>XP_005269463
          Length = 1586

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1437 ARRGGSQLS 1445
>XP_005269461
          Length = 1595

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1446 ARRGGSQLS 1454
>XP_006717623
          Length = 1595

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1446 ARRGGSQLS 1454
>XP_005269462
          Length = 1595

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR GGSQLS
Sbjct: 1446 ARRGGSQLS 1454
>NP_059119
          Length = 657

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RMGGSQL 8
           RMGG+QL
Sbjct: 564 RMGGNQL 570
>XP_005263119
          Length = 657

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RMGGSQL 8
           RMGG+QL
Sbjct: 564 RMGGNQL 570
>NP_003030
          Length = 501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   MGGSQLS 9
           MGG QLS
Sbjct: 285 MGGQQLS 291
>NP_004332
          Length = 2225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR+GG+ LS
Sbjct: 1985 ARLGGAVLS 1993
>NP_001494
          Length = 840

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MGGSQLS 9
           +GGSQLS
Sbjct: 355 IGGSQLS 361
>NP_001003760
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   MGGSQL 8
           MGGSQL
Sbjct: 518 MGGSQL 523
>XP_005257123
          Length = 803

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ARMGGS 6
           ARMGGS
Sbjct: 209 ARMGGS 214
>XP_005249164
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   MGGSQL 8
           MGGSQL
Sbjct: 518 MGGSQL 523
>XP_005249075
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MGGSQLS 9
           +GGSQLS
Sbjct: 192 IGGSQLS 198
>XP_005264615
          Length = 2162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR+GG+ LS
Sbjct: 1922 ARLGGAVLS 1930
>XP_006712164
          Length = 2179

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR+GG+ LS
Sbjct: 1939 ARLGGAVLS 1947
>XP_005264614
          Length = 2191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR+GG+ LS
Sbjct: 1951 ARLGGAVLS 1959
>XP_005264613
          Length = 2208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR+GG+ LS
Sbjct: 1968 ARLGGAVLS 1976
>XP_005264612
          Length = 2242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ARMGGSQLS 9
            AR+GG+ LS
Sbjct: 2002 ARLGGAVLS 2010
>XP_006710899
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   MGGSQLS 9
           MGG QLS
Sbjct: 275 MGGQQLS 281
>XP_005263548
          Length = 501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   MGGSQLS 9
           MGG QLS
Sbjct: 285 MGGQQLS 291
>NP_004713
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 370 GGSQLS 375
>NP_036425
          Length = 1479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 469 GGSQLS 474
>XP_005259447
          Length = 981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RMGGSQL 8
           R+GG+QL
Sbjct: 918 RLGGAQL 924
>XP_005259445
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RMGGSQL 8
           R+GG+QL
Sbjct: 963 RLGGAQL 969
>XP_005259444
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RMGGSQL 8
           R+GG+QL
Sbjct: 974 RLGGAQL 980
>XP_005259443
          Length = 1041

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RMGGSQL 8
           R+GG+QL
Sbjct: 978 RLGGAQL 984
>XP_005250748
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 145 GGSQLS 150
>XP_005250747
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 302 GGSQLS 307
>XP_006716238
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 377 GGSQLS 382
>XP_005250746
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 377 GGSQLS 382
>XP_006711959
          Length = 1388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 378 GGSQLS 383
>XP_005264764
          Length = 1455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   GGSQLS 9
           GGSQLS
Sbjct: 445 GGSQLS 450
>NP_001923
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 350 RLGGSQ 355
>NP_001002264
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>NP_150280
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>NP_001158238
          Length = 2789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 RMGGSQL 8
         R+GG QL
Sbjct: 2 RLGGGQL 8
>NP_001348
          Length = 1270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ARMGGSQ 7
           ARMGG +
Sbjct: 928 ARMGGEE 934
>NP_008816
          Length = 3703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   RMGGSQL 8
           R+GG QL
Sbjct: 916 RLGGGQL 922
>XP_006721980
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 148 RLGGSQ 153
>XP_006721978
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 350 RLGGSQ 355
>XP_005256014
          Length = 3702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   RMGGSQL 8
           R+GG QL
Sbjct: 916 RLGGGQL 922
>XP_006719959
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>XP_005266654
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>XP_005266653
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RMGGSQ 7
           R+GGSQ
Sbjct: 109 RLGGSQ 114
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.122    0.318 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 592,246
Number of extensions: 486
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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