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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     509
NP_001120652                                                           16    5631
NP_000251                                                              16    5631
NP_579875                                                              16    5631
NP_758847                                                              16    5631
XP_006718624                                                           16    5631
XP_005274069                                                           16    5631
XP_006718623                                                           16    5631
XP_006718622                                                           16    5631
XP_006718621                                                           16    5631
NP_821075                                                              15    9605
NP_443083                                                              15    9605
NP_821074                                                              15    9605
NP_001230405                                                           15    9605
NP_004711                                                              15    9605
NP_003080                                                              15    9605
NP_056481                                                              15    9605
XP_006723838                                                           15    9605
XP_005260450                                                           15    9605
XP_006723837                                                           15    9605
XP_006723836                                                           15    9605
XP_006723835                                                           15    9605
XP_005259234                                                           15    9605
XP_006719952                                                           15    9605
XP_006719951                                                           15    9605
XP_005266643                                                           15    9605

>NP_004251
          Length = 1208

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARLRRTFQ 8
            ARLRRTFQ
Sbjct: 1068 ARLRRTFQ 1075



>NP_001120652
          Length = 2175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>NP_000251
          Length = 2215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>NP_579875
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RLRRTFQ 8
           R+RRTF+
Sbjct: 156 RMRRTFE 162



>NP_758847
          Length = 425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RLRRTFQ 8
           R+RRTF+
Sbjct: 156 RMRRTFE 162



>XP_006718624
          Length = 2177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>XP_005274069
          Length = 2176

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>XP_006718623
          Length = 2189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>XP_006718622
          Length = 2190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>XP_006718621
          Length = 2225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    RLRRTF 7
            RLRRTF
Sbjct: 1230 RLRRTF 1235



>NP_821075
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ARLRRTFQ 8
            AR+R +FQ
Sbjct: 1087 ARIRNSFQ 1094



>NP_443083
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ARLRRTFQ 8
           AR+R +FQ
Sbjct: 977 ARIRNSFQ 984



>NP_821074
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ARLRRTFQ 8
            AR+R +FQ
Sbjct: 1095 ARIRNSFQ 1102



>NP_001230405
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ARLRRTFQ 8
            AR+R +FQ
Sbjct: 1060 ARIRNSFQ 1067



>NP_004711
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ARLRRTFQ 8
           A +RRTF+
Sbjct: 300 AEMRRTFR 307



>NP_003080
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARLRRTFQV 9
           ++LRR F+V
Sbjct: 117 SKLRREFEV 125



>NP_056481
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ARLRRTFQ 8
          ARLR  FQ
Sbjct: 9  ARLRTVFQ 16



>XP_006723838
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ARLRRTFQ 8
          ARLR  FQ
Sbjct: 9  ARLRTVFQ 16



>XP_005260450
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ARLRRTFQ 8
          ARLR  FQ
Sbjct: 9  ARLRTVFQ 16



>XP_006723837
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ARLRRTFQ 8
          ARLR  FQ
Sbjct: 25 ARLRTVFQ 32



>XP_006723836
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ARLRRTFQ 8
          ARLR  FQ
Sbjct: 37 ARLRTVFQ 44



>XP_006723835
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ARLRRTFQ 8
          ARLR  FQ
Sbjct: 37 ARLRTVFQ 44



>XP_005259234
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARLRRTFQV 9
           ++LRR F+V
Sbjct: 117 SKLRREFEV 125



>XP_006719952
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ARLRRTFQ 8
           AR+R +FQ
Sbjct: 977 ARIRNSFQ 984



>XP_006719951
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ARLRRTFQ 8
           AR+R +FQ
Sbjct: 977 ARIRNSFQ 984



>XP_005266643
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ARLRRTFQ 8
            AR+R +FQ
Sbjct: 1080 ARIRNSFQ 1087



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.146    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,485
Number of extensions: 488
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)