Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           19     665
NP_001277143                                                           19     665
NP_001319                                                              19     665
NP_001012632                                                           19     665
NP_001077383                                                           19     665
NP_001320                                                              19     665
NP_073713                                                              19     665
XP_005269629                                                           19     665
XP_005269628                                                           19     665
XP_005269627                                                           19     665
XP_005269626                                                           19     665
XP_006717706                                                           19     665
XP_005269625                                                           19     665
XP_005269624                                                           19     665
XP_006717705                                                           19     665
XP_005269622                                                           19     665
XP_005269621                                                           19     665
XP_006717704                                                           19     665
XP_005269619                                                           19     665
XP_005269618                                                           19     665
XP_005272320                                                           19     665
XP_005272319                                                           19     665
XP_005272318                                                           19     665
NP_060353                                                              17    3301
XP_006724603                                                           17    3301
XP_006724602                                                           17    3301
NP_004846                                                              17    4312
NP_004749                                                              17    4312
NP_077729                                                              17    4312
NP_001248764                                                           17    4312
XP_006722239                                                           17    4312
XP_006722238                                                           17    4312
XP_005257864                                                           17    4312
XP_006722237                                                           17    4312
XP_006722236                                                           17    4312
XP_006720840                                                           17    4312
NP_001136157                                                           16    7355
NP_055530                                                              16    7355
NP_001273568                                                           16    7355
NP_001074008                                                           16    7355
NP_208384                                                              16    7355
NP_001032412                                                           16    7355
NP_001273569                                                           16    7355
NP_055755                                                              16    7355
XP_006719010                                                           16    7355
XP_005271793                                                           16    7355
XP_006712501                                                           16    7355
NP_000960                                                              15    9605
NP_001238831                                                           15    9605
NP_003976                                                              15    9605
NP_001271224                                                           15    9605
NP_071370                                                              15    9605
NP_954857                                                              15    9605
NP_001277082                                                           15    9605
NP_001277078                                                           15    9605
NP_001277079                                                           15    9605
NP_116101                                                              15    9605
NP_001277081                                                           15    9605
NP_001277084                                                           15    9605
NP_001277080                                                           15    9605
NP_954858                                                              15    9605
NP_061888                                                              15    9605
NP_001277083                                                           15    9605
XP_005262467                                                           15    9605
XP_005262466                                                           15    9605
XP_005262465                                                           15    9605
XP_006716147                                                           15    9605
XP_006716146                                                           15    9605
XP_006716145                                                           15    9605
XP_006711877                                                           15    9605
NP_001094827                                                           15    9605
NP_078799                                                              15    9605
>NP_001277144
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>NP_001277143
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>NP_001319
          Length = 440

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 170 ARIRGETLG 178
>NP_001012632
          Length = 429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 159 ARIRGETLG 167
>NP_001077383
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>NP_001320
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>NP_073713
          Length = 985

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 716 ARIRGETLG 724
>XP_005269629
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269628
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269627
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269626
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_006717706
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269625
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269624
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_006717705
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269622
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269621
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_006717704
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269619
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005269618
          Length = 445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 176 ARIRGETLG 184
>XP_005272320
          Length = 430

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 159 ARIRGETLG 167
>XP_005272319
          Length = 430

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 159 ARIRGETLG 167
>XP_005272318
          Length = 441

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           ARIRGE LG
Sbjct: 170 ARIRGETLG 178
>NP_060353
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIRGEMLG 9
          R+RG++LG
Sbjct: 56 RLRGQLLG 63
>XP_006724603
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIRGEMLG 9
          R+RG++LG
Sbjct: 56 RLRGQLLG 63
>XP_006724602
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIRGEMLG 9
          R+RG++LG
Sbjct: 56 RLRGQLLG 63
>NP_004846
          Length = 554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ARIRGEMLG 9
          AR RG++LG
Sbjct: 50 ARRRGDLLG 58
>NP_004749
          Length = 1857

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 404 AELRGQLLG 412
>NP_077729
          Length = 1797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 344 AELRGQLLG 352
>NP_001248764
          Length = 1848

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 404 AELRGQLLG 412
>XP_006722239
          Length = 1630

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 404 AELRGQLLG 412
>XP_006722238
          Length = 1847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 344 AELRGQLLG 352
>XP_005257864
          Length = 1898

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 404 AELRGQLLG 412
>XP_006722237
          Length = 1900

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 404 AELRGQLLG 412
>XP_006722236
          Length = 1907

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ARIRGEMLG 9
           A +RG++LG
Sbjct: 404 AELRGQLLG 412
>XP_006720840
          Length = 382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ARIRGEMLG 9
          AR RG++LG
Sbjct: 50 ARRRGDLLG 58
>NP_001136157
          Length = 2087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ARIRGEMLG 9
           A   GEMLG
Sbjct: 737 ASFNGEMLG 745
>NP_055530
          Length = 1738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ARIRGEMLG 9
           A   GEMLG
Sbjct: 388 ASFNGEMLG 396
>NP_001273568
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ARIRGEML 8
          A++RGE+L
Sbjct: 75 AQLRGELL 82
>NP_001074008
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARIRGEM 7
           AR+RGE+
Sbjct: 454 ARLRGEL 460
>NP_208384
          Length = 2080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RIRGEMLG 9
           R+RG +LG
Sbjct: 617 RLRGRVLG 624
>NP_001032412
          Length = 2649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RIRGEMLG 9
            R+RG +LG
Sbjct: 1186 RLRGRVLG 1193
>NP_001273569
          Length = 401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ARIRGEML 8
          A++RGE+L
Sbjct: 38 AQLRGELL 45
>NP_055755
          Length = 547

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ARIRGEML 8
           A++RGE+L
Sbjct: 184 AQLRGELL 191
>XP_006719010
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  ARIRGEMLG 9
          A   GEMLG
Sbjct: 86 ASFNGEMLG 94
>XP_005271793
          Length = 2061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ARIRGEMLG 9
           A   GEMLG
Sbjct: 711 ASFNGEMLG 719
>XP_006712501
          Length = 1080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARIRGEM 7
           AR+RGE+
Sbjct: 454 ARLRGEL 460
>NP_000960
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ARIRGEML 8
          ARI G+M+
Sbjct: 67 ARIEGDMI 74
>NP_001238831
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RGEMLG 9
           RGE+LG
Sbjct: 118 RGELLG 123
>NP_003976
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RGEMLG 9
           RGE+LG
Sbjct: 118 RGELLG 123
>NP_001271224
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARIRGEMLG 9
           AR+ GE+ G
Sbjct: 676 ARLAGELAG 684
>NP_071370
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IRGEMLG 9
           IRG M+G
Sbjct: 226 IRGRMIG 232
>NP_954857
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277082
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277078
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277079
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_116101
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277081
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277084
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277080
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_954858
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_061888
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARIRGEMLG 9
           AR+ GE+ G
Sbjct: 684 ARLAGELAG 692
>NP_001277083
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARIRGEML 8
           ARI GE+L
Sbjct: 108 ARILGELL 115
>XP_005262467
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARIRGEM 7
           A+IRGE+
Sbjct: 272 AKIRGEL 278
>XP_005262466
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARIRGEM 7
           A+IRGE+
Sbjct: 272 AKIRGEL 278
>XP_005262465
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARIRGEM 7
           A+IRGE+
Sbjct: 281 AKIRGEL 287
>XP_006716147
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IRGEMLG 9
           IRG M+G
Sbjct: 226 IRGRMIG 232
>XP_006716146
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IRGEMLG 9
           IRG M+G
Sbjct: 226 IRGRMIG 232
>XP_006716145
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IRGEMLG 9
           IRG M+G
Sbjct: 226 IRGRMIG 232
>XP_006711877
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RGEMLG 9
           +GEMLG
Sbjct: 673 KGEMLG 678
>NP_001094827
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARIRGEM 7
           A+IRGE+
Sbjct: 272 AKIRGEL 278
>NP_078799
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARIRGEMLG 9
           AR+ GE+ G
Sbjct: 209 ARLEGELKG 217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.149    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,567
Number of extensions: 615
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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