Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              18    1482
NP_001155130                                                           16    7355
NP_001155131                                                           16    7355
NP_001155128                                                           16    7355
NP_001155129                                                           16    7355
NP_001123644                                                           16    7355
NP_001123645                                                           16    7355
NP_005366                                                              16    7355
XP_006715558                                                           16    7355
NP_006039                                                              15    9605
NP_001099032                                                           15    9605
NP_055733                                                              15    9605
NP_003743                                                              15    9605
NP_001254503                                                           15    9605
NP_001273407                                                           15    9605
NP_001032897                                                           15    9605
NP_057149                                                              15    9605
NP_001186071                                                           15    9605
NP_001093131                                                           15    9605
XP_005255592                                                           15    9605
XP_006720498                                                           15    9605
XP_005263479                                                           15    9605
>NP_004295
          Length = 1620

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AREILLMST 9
           AREILLM T
Sbjct: 372 AREILLMPT 380
>NP_001155130
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001155131
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001155128
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001155129
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001123644
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001123645
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_005366
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>XP_006715558
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_006039
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+L+MST
Sbjct: 208 EVLMMST 214
>NP_001099032
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+L+MST
Sbjct: 208 EVLMMST 214
>NP_055733
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   REILLMS 8
           REI+LMS
Sbjct: 336 REIVLMS 342
>NP_003743
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_001254503
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_001273407
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 575 ARDLMLMS 582
>NP_001032897
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_057149
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AREILLMS 8
           ARE+LL S
Sbjct: 115 AREVLLAS 122
>NP_001186071
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_001093131
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 586 ARDLMLMS 593
>XP_005255592
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AREILLMS 8
           AR+++LMS
Sbjct: 586 ARDLMLMS 593
>XP_006720498
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  REILLMS 8
          REI+LMS
Sbjct: 64 REIVLMS 70
>XP_005263479
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EILLMST 9
           E+L+MST
Sbjct: 208 EVLMMST 214
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.131    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 322,321
Number of extensions: 263
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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