Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_689585                                                              17    2528
NP_114088                                                              17    2528
NP_061721                                                              17    2528
NP_001398                                                              16    5631
NP_064546                                                              16    5631
NP_001155955                                                           16    5631
NP_116753                                                              16    5631
NP_116754                                                              16    5631
NP_001265548                                                           16    5631
NP_116755                                                              16    5631
NP_116749                                                              16    5631
NP_001161834                                                           16    5631
NP_001161832                                                           16    5631
NP_116750                                                              16    5631
NP_001161833                                                           16    5631
NP_116751                                                              16    5631
NP_001161835                                                           16    5631
NP_055337                                                              16    5631
NP_001165405                                                           16    7355
NP_001165404                                                           16    7355
NP_071407                                                              16    7355
NP_543016                                                              16    7355
NP_689854                                                              16    7355
XP_006719336                                                           16    7355
XP_006719335                                                           16    7355
XP_006718005                                                           16    7355
XP_006718004                                                           16    7355
XP_006718003                                                           16    7355
XP_005275746                                                           16    7355
XP_003403671                                                           16    7355
XP_006710003                                                           16    7355
NP_473446                                                              15    9605
NP_078858                                                              15    9605
NP_001278232                                                           15    9605
NP_001278214                                                           15    9605
NP_003731                                                              15    9605
NP_002638                                                              15    9605
NP_001399                                                              15    9605
XP_005249513                                                           15    9605
XP_006710468                                                           15    9605
XP_005270637                                                           15    9605
NP_061741                                                              15    9605
NP_114475                                                              15    9605
NP_114443                                                              15    9605
NP_061742                                                              15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1252 AQVNLTVVD 1260
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1252 AQVNLTVVD 1260
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1321 AQVNLTVVD 1329
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1321 AQVNLTVVD 1329
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1262 AQVNLTVVD 1270
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1331 AQVNLTVVD 1339
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1331 AQVNLTVVD 1339
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQVTLTVVD 9
            AQV LTVVD
Sbjct: 1331 AQVNLTVVD 1339
>NP_689585
          Length = 1437

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            Q+TLT+VD
Sbjct: 1090 QITLTLVD 1097
>NP_114088
          Length = 818

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           AQVT+ VVD
Sbjct: 217 AQVTIIVVD 225
>NP_061721
          Length = 963

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           AQVT+ VVD
Sbjct: 217 AQVTIIVVD 225
>NP_001398
          Length = 3312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A VT+TV+D
Sbjct: 740 ASVTVTVLD 748
>NP_064546
          Length = 150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VTLTVVD 9
          VT+TVVD
Sbjct: 22 VTMTVVD 28
>NP_001155955
          Length = 96

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VTLTVVD 9
          VT+TVVD
Sbjct: 22 VTMTVVD 28
>NP_116753
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 678 AKVTINVVD 686
>NP_116754
          Length = 1048

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 689 AKVTINVVD 697
>NP_001265548
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 678 AKVTINVVD 686
>NP_116755
          Length = 1340

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 689 AKVTINVVD 697
>NP_116749
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_001161834
          Length = 1310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_001161832
          Length = 1339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_116750
          Length = 1347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_001161833
          Length = 1065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_116751
          Length = 1337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_001161835
          Length = 1329

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_055337
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A+VT+ VVD
Sbjct: 657 AKVTINVVD 665
>NP_001165405
          Length = 1079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QVTLTVVD 9
          +VTL+V+D
Sbjct: 15 EVTLSVID 22
>NP_001165404
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QVTLTVVD 9
          +VTL+V+D
Sbjct: 15 EVTLSVID 22
>NP_071407
          Length = 3354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2255 EVTLSVID 2262
>NP_543016
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QVTLTVVD 9
           QVT+ VVD
Sbjct: 126 QVTIEVVD 133
>NP_689854
          Length = 1835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QVTLTVV 8
            QVT+TVV
Sbjct: 1171 QVTITVV 1177
>XP_006719336
          Length = 1779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QVTLTVV 8
            QVT+TVV
Sbjct: 1115 QVTITVV 1121
>XP_006719335
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QVTLTVV 8
            QVT+TVV
Sbjct: 1171 QVTITVV 1177
>XP_006718005
          Length = 3397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2298 EVTLSVID 2305
>XP_006718004
          Length = 3399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2300 EVTLSVID 2307
>XP_006718003
          Length = 3419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2320 EVTLSVID 2327
>XP_005275746
          Length = 3352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2253 EVTLSVID 2260
>XP_003403671
          Length = 3354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2255 EVTLSVID 2262
>XP_006710003
          Length = 3374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QVTLTVVD 9
            +VTL+V+D
Sbjct: 2275 EVTLSVID 2282
>NP_473446
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VTLTVVD 9
          +TLT+VD
Sbjct: 44 ITLTLVD 50
>NP_078858
          Length = 4981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A VT+TV+D
Sbjct: 777 AIVTITVLD 785
>NP_001278232
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A VT+TV+D
Sbjct: 777 AIVTITVLD 785
>NP_001278214
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           A VT+TV+D
Sbjct: 777 AIVTITVLD 785
>NP_003731
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQVTLTVV 8
           AQ+T TV+
Sbjct: 158 AQITCTVI 165
>NP_002638
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQVTLTVVD 9
           AQV LT+ D
Sbjct: 104 AQVALTIWD 112
>NP_001399
          Length = 2923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVTLTVVD 9
           +VT+TV+D
Sbjct: 906 EVTVTVLD 913
>XP_005249513
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQVTLTVV 8
           AQ+T TV+
Sbjct: 155 AQITCTVI 162
>XP_006710468
          Length = 2916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVTLTVVD 9
           +VT+TV+D
Sbjct: 906 EVTVTVLD 913
>XP_005270637
          Length = 2921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVTLTVVD 9
           +VT+TV+D
Sbjct: 906 EVTVTVLD 913
>NP_061741
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTLTVVD 9
           +TLTV+D
Sbjct: 420 ITLTVMD 426
>NP_114475
          Length = 818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           AQ+ +TV+D
Sbjct: 226 AQILVTVLD 234
>NP_114443
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTLTVVD 9
           +TLTV+D
Sbjct: 420 ITLTVMD 426
>NP_061742
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQVTLTVVD 9
           AQ+ +TV+D
Sbjct: 226 AQILVTVLD 234
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.126    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 260,134
Number of extensions: 275
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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