Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           20     509
NP_001277143                                                           20     509
NP_001319                                                              20     509
NP_001012632                                                           20     509
NP_001077383                                                           20     509
NP_001320                                                              20     509
NP_073713                                                              20     509
XP_005269629                                                           20     509
XP_005269628                                                           20     509
XP_005269627                                                           20     509
XP_005269626                                                           20     509
XP_006717706                                                           20     509
XP_005269625                                                           20     509
XP_005269624                                                           20     509
XP_006717705                                                           20     509
XP_005269622                                                           20     509
XP_005269621                                                           20     509
XP_006717704                                                           20     509
XP_005269619                                                           20     509
XP_005269618                                                           20     509
XP_005272320                                                           20     509
XP_005272319                                                           20     509
XP_005272318                                                           20     509
NP_002069                                                              18    1482
NP_001166184                                                           18    1482
XP_005265132                                                           18    1482
XP_005265131                                                           18    1482
XP_006713173                                                           18    1482
XP_005265130                                                           18    1482
XP_005265129                                                           18    1482
XP_005265128                                                           18    1482
XP_005265127                                                           18    1482
XP_005265126                                                           18    1482
NP_003326                                                              17    2528
XP_005265487                                                           17    2528
XP_006713384                                                           17    2528
NP_060796                                                              17    4312
NP_001258604                                                           17    4312
NP_055642                                                              17    4312
XP_005250075                                                           17    4312
XP_005250074                                                           17    4312
XP_005245703                                                           17    4312
XP_006711736                                                           17    4312
XP_005245701                                                           17    4312
XP_005245700                                                           17    4312
NP_006104                                                              16    7355
NP_001996                                                              16    7355
NP_001137257                                                           16    7355
NP_002389                                                              16    7355
NP_036553                                                              16    7355
NP_057590                                                              16    7355
NP_001137255                                                           16    7355
NP_001137256                                                           16    7355
NP_001001671                                                           16    7355
XP_005254939                                                           16    7355
XP_005254938                                                           16    7355
XP_005254937                                                           16    7355
XP_005254934                                                           16    7355
XP_006718325                                                           16    7355
XP_006718324                                                           16    7355
XP_005264380                                                           16    7355
XP_005264379                                                           16    7355
XP_005264378                                                           16    7355
XP_005270418                                                           16    7355
XP_005270417                                                           16    7355
XP_005270416                                                           16    7355
NP_060565                                                              16    7355
NP_003244                                                              15    9605
NP_005392                                                              15    9605
NP_060613                                                              15    9605
XP_005261097                                                           15    9605
XP_005261096                                                           15    9605
XP_005261095                                                           15    9605
XP_005261094                                                           15    9605
>NP_001277144
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>NP_001277143
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>NP_001319
          Length = 440

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 56 AQSTQEIHE 64
>NP_001012632
          Length = 429

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 45 AQSTQEIHE 53
>NP_001077383
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>NP_001320
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>NP_073713
          Length = 985

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQSMQEIHE 9
           AQS QEIHE
Sbjct: 602 AQSTQEIHE 610
>XP_005269629
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269628
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269627
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269626
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_006717706
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269625
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269624
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_006717705
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269622
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269621
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_006717704
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269619
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005269618
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 62 AQSTQEIHE 70
>XP_005272320
          Length = 430

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 45 AQSTQEIHE 53
>XP_005272319
          Length = 430

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 45 AQSTQEIHE 53
>XP_005272318
          Length = 441

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AQSMQEIHE 9
          AQS QEIHE
Sbjct: 56 AQSTQEIHE 64
>NP_002069
          Length = 2230

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1055 AEELQEIHE 1063
>NP_001166184
          Length = 2243

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1077 AEELQEIHE 1085
>XP_005265132
          Length = 2214

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1039 AEELQEIHE 1047
>XP_005265131
          Length = 2245

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1077 AEELQEIHE 1085
>XP_006713173
          Length = 2250

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1075 AEELQEIHE 1083
>XP_005265130
          Length = 2252

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1077 AEELQEIHE 1085
>XP_005265129
          Length = 2269

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1094 AEELQEIHE 1102
>XP_005265128
          Length = 2278

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1110 AEELQEIHE 1118
>XP_005265127
          Length = 2283

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1110 AEELQEIHE 1118
>XP_005265126
          Length = 2285

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQSMQEIHE 9
            A+ +QEIHE
Sbjct: 1110 AEELQEIHE 1118
>NP_003326
          Length = 1012

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQSMQEIH 8
           AQS QE+H
Sbjct: 278 AQSSQEVH 285
>XP_005265487
          Length = 987

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQSMQEIH 8
           AQS QE+H
Sbjct: 278 AQSSQEVH 285
>XP_006713384
          Length = 1005

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQSMQEIH 8
           AQS QE+H
Sbjct: 278 AQSSQEVH 285
>NP_060796
          Length = 329

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           Q+MQE+H
Sbjct: 238 QAMQELH 244
>NP_001258604
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           +SMQE+H
Sbjct: 464 KSMQEVH 470
>NP_055642
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           +SMQE+H
Sbjct: 464 KSMQEVH 470
>XP_005250075
          Length = 190

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           Q+MQE+H
Sbjct: 99  QAMQELH 105
>XP_005250074
          Length = 343

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           Q+MQE+H
Sbjct: 252 QAMQELH 258
>XP_005245703
          Length = 474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           +SMQE+H
Sbjct: 128 KSMQEVH 134
>XP_006711736
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           +SMQE+H
Sbjct: 464 KSMQEVH 470
>XP_005245701
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           +SMQE+H
Sbjct: 464 KSMQEVH 470
>XP_005245700
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSMQEIH 8
           +SMQE+H
Sbjct: 464 KSMQEVH 470
>NP_006104
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MQEIHE 9
           MQEIH+
Sbjct: 249 MQEIHD 254
>NP_001996
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 210 RSLQDLHE 217
>NP_001137257
          Length = 694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 152 RSLQDLHE 159
>NP_002389
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AQSMQEIH 8
          A+SMQ +H
Sbjct: 30 ARSMQPVH 37
>NP_036553
          Length = 1914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QSMQEIHE 9
           QS+QE H+
Sbjct: 155 QSLQESHD 162
>NP_057590
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQSMQEIHE 9
           A+ +QEI+E
Sbjct: 112 AEELQEIYE 120
>NP_001137255
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 152 RSLQDLHE 159
>NP_001137256
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 210 RSLQDLHE 217
>NP_001001671
          Length = 1313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    AQSMQEIH 8
            AQS +E+H
Sbjct: 1035 AQSSEELH 1042
>XP_005254939
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 210 RSLQDLHE 217
>XP_005254938
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 152 RSLQDLHE 159
>XP_005254937
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 152 RSLQDLHE 159
>XP_005254934
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSMQEIHE 9
           +S+Q++HE
Sbjct: 210 RSLQDLHE 217
>XP_006718325
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQSMQEIHE 9
           A+ +QEI+E
Sbjct: 135 AEELQEIYE 143
>XP_006718324
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQSMQEIHE 9
           A+ +QEI+E
Sbjct: 161 AEELQEIYE 169
>XP_005264380
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AQSMQEIH 8
          A+SMQ +H
Sbjct: 46 ARSMQPVH 53
>XP_005264379
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AQSMQEIH 8
          A+SMQ +H
Sbjct: 30 ARSMQPVH 37
>XP_005264378
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AQSMQEIH 8
          A+SMQ +H
Sbjct: 46 ARSMQPVH 53
>XP_005270418
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MQEIHE 9
           MQEIH+
Sbjct: 249 MQEIHD 254
>XP_005270417
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MQEIHE 9
           MQEIH+
Sbjct: 155 MQEIHD 160
>XP_005270416
          Length = 805

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MQEIHE 9
           MQEIH+
Sbjct: 249 MQEIHD 254
>NP_060565
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQSMQEIHE 9
           A+ +QEI+E
Sbjct: 128 AEELQEIYE 136
>NP_003244
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MQEIHE 9
            MQ+IHE
Sbjct: 1234 MQKIHE 1239
>NP_005392
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QSMQEIHE 9
           QS+QE+ E
Sbjct: 619 QSLQEVSE 626
>NP_060613
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QSMQEIH 8
           + MQEIH
Sbjct: 686 RQMQEIH 692
>XP_005261097
          Length = 1452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MQEIHE 9
            MQ+IHE
Sbjct: 1234 MQKIHE 1239
>XP_005261096
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MQEIHE 9
            MQ+IHE
Sbjct: 1234 MQKIHE 1239
>XP_005261095
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MQEIHE 9
            MQ+IHE
Sbjct: 1234 MQKIHE 1239
>XP_005261094
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MQEIHE 9
            MQ+IHE
Sbjct: 1234 MQKIHE 1239
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.110    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 488,530
Number of extensions: 743
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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