Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     299
NP_671714                                                              20     299
XP_006715890                                                           20     299
XP_005250160                                                           20     299
XP_005250159                                                           20     299
NP_861521                                                              17    2528
NP_001268373                                                           17    2528
NP_861520                                                              17    2528
NP_001268374                                                           17    2528
NP_008997                                                              17    2528
NP_001106970                                                           17    4312
NP_878250                                                              17    4312
XP_006720131                                                           17    4312
NP_997192                                                              16    5631
XP_006717380                                                           16    5631
NP_001128360                                                           16    7355
NP_003613                                                              16    7355
NP_001185845                                                           16    7355
NP_803193                                                              16    7355
NP_065114                                                              16    7355
NP_001185844                                                           16    7355
NP_006769                                                              16    7355
XP_005256935                                                           16    7355
XP_006719224                                                           16    7355
XP_006719222                                                           16    7355
XP_005253573                                                           16    7355
XP_005253572                                                           16    7355
XP_005253571                                                           16    7355
XP_005253568                                                           16    7355
XP_005253567                                                           16    7355
XP_005253566                                                           16    7355
XP_005253565                                                           16    7355
XP_005253564                                                           16    7355
XP_005253563                                                           16    7355
XP_005253562                                                           16    7355
NP_055531                                                              16    7355
NP_439893                                                              16    7355
NP_003102                                                              15    9605
NP_001017371                                                           15    9605
NP_001166183                                                           15    9605
NP_001170946                                                           15    9605
NP_689794                                                              15    9605
NP_733779                                                              15    9605
NP_008861                                                              15    9605
NP_001271226                                                           15    9605
NP_001271227                                                           15    9605
XP_006724530                                                           15    9605
XP_005274508                                                           15    9605
XP_005254507                                                           15    9605
XP_005254506                                                           15    9605
XP_005254505                                                           15    9605
XP_006720635                                                           15    9605
XP_006720634                                                           15    9605
XP_006715677                                                           15    9605
NP_004564                                                              15    9605
>NP_005742
          Length = 3907

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AQMQSSDGT 9
            AQ+QSSDGT
Sbjct: 3324 AQLQSSDGT 3332
>NP_671714
          Length = 3899

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AQMQSSDGT 9
            AQ+QSSDGT
Sbjct: 3316 AQLQSSDGT 3324
>XP_006715890
          Length = 3860

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AQMQSSDGT 9
            AQ+QSSDGT
Sbjct: 3277 AQLQSSDGT 3285
>XP_005250160
          Length = 3939

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AQMQSSDGT 9
            AQ+QSSDGT
Sbjct: 3356 AQLQSSDGT 3364
>XP_005250159
          Length = 3952

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AQMQSSDGT 9
            AQ+QSSDGT
Sbjct: 3369 AQLQSSDGT 3377
>NP_861521
          Length = 76

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QMQSSDGT 9
          Q QSSDGT
Sbjct: 66 QPQSSDGT 73
>NP_001268373
          Length = 76

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QMQSSDGT 9
          Q QSSDGT
Sbjct: 66 QPQSSDGT 73
>NP_861520
          Length = 76

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QMQSSDGT 9
          Q QSSDGT
Sbjct: 66 QPQSSDGT 73
>NP_001268374
          Length = 76

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QMQSSDGT 9
          Q QSSDGT
Sbjct: 66 QPQSSDGT 73
>NP_008997
          Length = 76

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QMQSSDGT 9
          Q QSSDGT
Sbjct: 66 QPQSSDGT 73
>NP_001106970
          Length = 956

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+S DGT
Sbjct: 492 QMESYDGT 499
>NP_878250
          Length = 727

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+S DGT
Sbjct: 263 QMESYDGT 270
>XP_006720131
          Length = 957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+S DGT
Sbjct: 493 QMESYDGT 500
>NP_997192
          Length = 507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQMQSSDGT 9
           AQ+++SDG+
Sbjct: 315 AQLRASDGS 323
>XP_006717380
          Length = 512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQMQSSDGT 9
           AQ+++SDG+
Sbjct: 315 AQLRASDGS 323
>NP_001128360
          Length = 1358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QMQSSDGT 9
          QM+SS+G+
Sbjct: 22 QMESSEGS 29
>NP_003613
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 955 QMEDSEGT 962
>NP_001185845
          Length = 980

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 930 QMEDSEGT 937
>NP_803193
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 961 QMEDSEGT 968
>NP_065114
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QMQSSDG 8
           ++QSSDG
Sbjct: 170 ELQSSDG 176
>NP_001185844
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 808 QMEDSEGT 815
>NP_006769
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQMQSSDG 8
           AQ++S DG
Sbjct: 205 AQLESQDG 212
>XP_005256935
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQMQSSDG 8
           AQ+QS DG
Sbjct: 335 AQVQSVDG 342
>XP_006719224
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 941 QMEDSEGT 948
>XP_006719222
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 833 QMEDSEGT 840
>XP_005253573
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 941 QMEDSEGT 948
>XP_005253572
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 944 QMEDSEGT 951
>XP_005253571
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 952 QMEDSEGT 959
>XP_005253568
          Length = 1014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 964 QMEDSEGT 971
>XP_005253567
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 975 QMEDSEGT 982
>XP_005253566
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 975 QMEDSEGT 982
>XP_005253565
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 976 QMEDSEGT 983
>XP_005253564
          Length = 1033

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 983 QMEDSEGT 990
>XP_005253563
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 986 QMEDSEGT 993
>XP_005253562
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           QM+ S+GT
Sbjct: 986 QMEDSEGT 993
>NP_055531
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQMQSSDG 8
           AQ+QS DG
Sbjct: 409 AQVQSVDG 416
>NP_439893
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQMQSSDG 8
           AQ++S DG
Sbjct: 205 AQLESQDG 212
>NP_003102
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QMQSSDG 8
           Q+QS+DG
Sbjct: 175 QIQSADG 181
>NP_001017371
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QMQSSDG 8
           Q+QS+DG
Sbjct: 107 QIQSADG 113
>NP_001166183
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QMQSSDG 8
           Q+QS+DG
Sbjct: 172 QIQSADG 178
>NP_001170946
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AQMQSSDGT 9
           A+M+ S GT
Sbjct: 347 AEMEQSSGT 355
>NP_689794
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AQMQSSDGT 9
           A+M+ S GT
Sbjct: 410 AEMEQSSGT 418
>NP_733779
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QMQSSDG 8
          ++QSSDG
Sbjct: 5  KLQSSDG 11
>NP_008861
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QMQSSDG 8
          ++QSSDG
Sbjct: 5  KLQSSDG 11
>NP_001271226
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 524 KMQSDEGT 531
>NP_001271227
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
>XP_006724530
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AQMQSSDGT 9
           A+M+ S GT
Sbjct: 410 AEMEQSSGT 418
>XP_005274508
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AQMQSSDGT 9
           A+M+ S GT
Sbjct: 410 AEMEQSSGT 418
>XP_005254507
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
>XP_005254506
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
>XP_005254505
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
>XP_006720635
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
>XP_006720634
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
>XP_006715677
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QMQSSDG 8
           Q+Q+SDG
Sbjct: 241 QIQTSDG 247
>NP_004564
          Length = 1185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QMQSSDGT 9
           +MQS +GT
Sbjct: 528 KMQSDEGT 535
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.101    0.244 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,502
Number of extensions: 579
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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