Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006710143                                                           19     665
XP_006710142                                                           19     665
XP_006710141                                                           19     665
XP_006726410                                                           18    1935
XP_006711164                                                           18    1935
NP_001277935                                                           17    3301
XP_005264907                                                           17    3301
XP_006713022                                                           17    3301
XP_005264906                                                           17    3301
XP_005264904                                                           17    3301
NP_443185                                                              17    3301
NP_001159751                                                           17    4312
NP_055686                                                              17    4312
NP_001120932                                                           17    4312
NP_001265578                                                           16    7355
NP_001278220                                                           15    9605
NP_003591                                                              15    9605
NP_940838                                                              15    9605
NP_940837                                                              15    9605
NP_940839                                                              15    9605
NP_940835                                                              15    9605
NP_940836                                                              15    9605
NP_001269588                                                           15    9605
NP_001029082                                                           15    9605
NP_060414                                                              15    9605
XP_006723935                                                           15    9605
XP_005260591                                                           15    9605
XP_006723934                                                           15    9605
XP_005253054                                                           15    9605
XP_005246920                                                           15    9605
XP_006711587                                                           15    9605
XP_005273306                                                           15    9605
NP_665702                                                              15    9605
NP_004610                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1406 AQLPKNGLE 1414
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1450 AQLPKNGLE 1458
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1450 AQLPKNGLE 1458
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1406 AQLPKNGLE 1414
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLSKNGLE 9
           AQL KNGLE
Sbjct: 457 AQLPKNGLE 465
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1406 AQLPKNGLE 1414
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1515 AQLPKNGLE 1523
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1449 AQLPKNGLE 1457
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1450 AQLPKNGLE 1458
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1453 AQLPKNGLE 1461
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1503 AQLPKNGLE 1511
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1515 AQLPKNGLE 1523
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1516 AQLPKNGLE 1524
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1612 AQLPKNGLE 1620
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL KNGLE
Sbjct: 1613 AQLPKNGLE 1621
>XP_006710143
          Length = 562

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLSKNGLE 9
           AQL KNGLE
Sbjct: 292 AQLPKNGLE 300
>XP_006710142
          Length = 671

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLSKNGLE 9
           AQL KNGLE
Sbjct: 401 AQLPKNGLE 409
>XP_006710141
          Length = 672

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLSKNGLE 9
           AQL KNGLE
Sbjct: 402 AQLPKNGLE 410
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL +NGLE
Sbjct: 1253 AQLPENGLE 1261
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    AQLSKNGLE 9
            AQL +NGLE
Sbjct: 1253 AQLPENGLE 1261
>NP_001277935
          Length = 392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QLSKNGLE 9
           QLS NGLE
Sbjct: 169 QLSGNGLE 176
>XP_005264907
          Length = 259

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSKNGLE 9
           LSKNG+E
Sbjct: 95  LSKNGIE 101
>XP_006713022
          Length = 259

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSKNGLE 9
           LSKNG+E
Sbjct: 95  LSKNGIE 101
>XP_005264906
          Length = 259

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSKNGLE 9
           LSKNG+E
Sbjct: 95  LSKNGIE 101
>XP_005264904
          Length = 259

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSKNGLE 9
           LSKNG+E
Sbjct: 95  LSKNGIE 101
>NP_443185
          Length = 259

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSKNGLE 9
           LSKNG+E
Sbjct: 95  LSKNGIE 101
>NP_001159751
          Length = 1201

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QLSKNGLE 9
            +LSKNG E
Sbjct: 1151 ELSKNGTE 1158
>NP_055686
          Length = 1198

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QLSKNGLE 9
            +LSKNG E
Sbjct: 1148 ELSKNGTE 1155
>NP_001120932
          Length = 1202

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QLSKNGLE 9
            +LSKNG E
Sbjct: 1152 ELSKNGTE 1159
>NP_001265578
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQ+S  GLE
Sbjct: 343 AQISTEGLE 351
>NP_001278220
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLSKNGLE 9
           ++S+NGLE
Sbjct: 206 KVSENGLE 213
>NP_003591
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>NP_940838
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>NP_940837
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>NP_940839
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>NP_940835
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>NP_940836
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>NP_001269588
          Length = 1355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLSKNGLE 9
           ++SK+GLE
Sbjct: 454 KISKSGLE 461
>NP_001029082
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AQLSKN 6
           AQLSKN
Sbjct: 385 AQLSKN 390
>NP_060414
          Length = 1287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLSKNGLE 9
           ++SK+GLE
Sbjct: 386 KISKSGLE 393
>XP_006723935
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>XP_005260591
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 167 AQLEKAGVE 175
>XP_006723934
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AQLSKNGLE 9
           AQL K G+E
Sbjct: 183 AQLEKAGVE 191
>XP_005253054
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLSKNGLE 9
           ++SK+GLE
Sbjct: 474 KISKSGLE 481
>XP_005246920
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLSKNGLE 9
           QLS NGL+
Sbjct: 442 QLSFNGLQ 449
>XP_006711587
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AQLSKN 6
           AQLSKN
Sbjct: 418 AQLSKN 423
>XP_005273306
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AQLSKN 6
           AQLSKN
Sbjct: 449 AQLSKN 454
>NP_665702
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AQLSKN 6
           AQLSKN
Sbjct: 385 AQLSKN 390
>NP_004610
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AQLSKN 6
           AQLSKN
Sbjct: 385 AQLSKN 390
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.119    0.288 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 500,570
Number of extensions: 527
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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