Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006710602                                                           17    4312
XP_006710601                                                           17    4312
XP_006710598                                                           17    4312
XP_006710597                                                           17    4312
XP_006710596                                                           17    4312
XP_006710595                                                           17    4312
XP_006710594                                                           17    4312
XP_006710593                                                           17    4312
XP_006710592                                                           17    4312
XP_006710591                                                           17    4312
XP_006710590                                                           17    4312
XP_006710589                                                           17    4312
XP_006710588                                                           17    4312
XP_006710586                                                           17    4312
XP_006710585                                                           17    4312
XP_005270755                                                           17    4312
XP_006710584                                                           17    4312
XP_005270754                                                           17    4312
XP_005270753                                                           17    4312
XP_006710583                                                           17    4312
XP_005270752                                                           17    4312
XP_006710582                                                           17    4312
XP_005270751                                                           17    4312
NP_004095                                                              16    5631
NP_001077083                                                           16    5631
NP_439896                                                              16    5631
XP_006721083                                                           16    5631
XP_006715391                                                           16    5631
NP_001277155                                                           16    7355
NP_001277156                                                           16    7355
NP_055998                                                              16    7355
NP_001158136                                                           16    7355
NP_001131074                                                           16    7355
NP_057039                                                              16    7355
NP_056002                                                              16    7355
XP_006714675                                                           16    7355
XP_006714673                                                           16    7355
XP_006714672                                                           16    7355
XP_006714670                                                           16    7355
XP_006714669                                                           16    7355
XP_006714668                                                           16    7355
XP_006714667                                                           16    7355
XP_006714666                                                           16    7355
XP_005248555                                                           16    7355
XP_006714665                                                           16    7355
XP_006714020                                                           16    7355
XP_005248200                                                           16    7355
XP_006714019                                                           16    7355
XP_006712091                                                           16    7355
XP_005264408                                                           16    7355
NP_002486                                                              15    9605
NP_079334                                                              15    9605
NP_001243529                                                           15    9605
NP_001269307                                                           15    9605
NP_001243528                                                           15    9605
NP_001243530                                                           15    9605
>XP_006710602
          Length = 7391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3543 AQLDALAF 3550
>XP_006710601
          Length = 4720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_006710598
          Length = 7553

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3533 AQLDALAF 3540
>XP_006710597
          Length = 7451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3543 AQLDALAF 3550
>XP_006710596
          Length = 7512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3492 AQLDALAF 3499
>XP_006710595
          Length = 7526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3506 AQLDALAF 3513
>XP_006710594
          Length = 7528

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3508 AQLDALAF 3515
>XP_006710593
          Length = 7539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3519 AQLDALAF 3526
>XP_006710592
          Length = 7544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3524 AQLDALAF 3531
>XP_006710591
          Length = 7558

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3538 AQLDALAF 3545
>XP_006710590
          Length = 7563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3543 AQLDALAF 3550
>XP_006710589
          Length = 7595

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3575 AQLDALAF 3582
>XP_006710588
          Length = 7614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_006710586
          Length = 7645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_006710585
          Length = 7657

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_005270755
          Length = 7663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_006710584
          Length = 7686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_005270754
          Length = 7694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_005270753
          Length = 7700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_006710583
          Length = 7702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_005270752
          Length = 7717

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_006710582
          Length = 7720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>XP_005270751
          Length = 7723

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQLDAVSF 8
            AQLDA++F
Sbjct: 3703 AQLDALAF 3710
>NP_004095
          Length = 2511

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QLDAVSFA 9
            QLD+ SFA
Sbjct: 1714 QLDSTSFA 1721
>NP_001077083
          Length = 523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQLDAVS 7
           AQLDA+S
Sbjct: 433 AQLDAIS 439
>NP_439896
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDAVSFA 9
           +DAVSFA
Sbjct: 139 MDAVSFA 145
>XP_006721083
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQLDAVS 7
           AQLDA+S
Sbjct: 433 AQLDAIS 439
>XP_006715391
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDAVSFA 9
           +DAVSFA
Sbjct: 139 MDAVSFA 145
>NP_001277155
          Length = 2417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1542 AQMSAVSF 1549
>NP_001277156
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1487 AQMSAVSF 1494
>NP_055998
          Length = 2434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1559 AQMSAVSF 1566
>NP_001158136
          Length = 2623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1748 AQMSAVSF 1755
>NP_001131074
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           QLD VSF+
Sbjct: 203 QLDPVSFS 210
>NP_057039
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           QLD VSF+
Sbjct: 226 QLDPVSFS 233
>NP_056002
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           Q+DA SFA
Sbjct: 942 QIDAPSFA 949
>XP_006714675
          Length = 2275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1400 AQMSAVSF 1407
>XP_006714673
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1487 AQMSAVSF 1494
>XP_006714672
          Length = 2414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1539 AQMSAVSF 1546
>XP_006714670
          Length = 2425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1550 AQMSAVSF 1557
>XP_006714669
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1554 AQMSAVSF 1561
>XP_006714668
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1554 AQMSAVSF 1561
>XP_006714667
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1557 AQMSAVSF 1564
>XP_006714666
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1557 AQMSAVSF 1564
>XP_005248555
          Length = 2626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1751 AQMSAVSF 1758
>XP_006714665
          Length = 2651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLDAVSF 8
            AQ+ AVSF
Sbjct: 1776 AQMSAVSF 1783
>XP_006714020
          Length = 1097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           Q+DA SFA
Sbjct: 907 QIDAPSFA 914
>XP_005248200
          Length = 1103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           Q+DA SFA
Sbjct: 942 QIDAPSFA 949
>XP_006714019
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           Q+DA SFA
Sbjct: 914 QIDAPSFA 921
>XP_006712091
          Length = 180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           QLD VSF+
Sbjct: 109 QLDPVSFS 116
>XP_005264408
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVSFA 9
           QLD VSF+
Sbjct: 226 QLDPVSFS 233
>NP_002486
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DAVSFA 9
           DAVSFA
Sbjct: 133 DAVSFA 138
>NP_079334
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDAVSF 8
           LDAVSF
Sbjct: 705 LDAVSF 710
>NP_001243529
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDAVSF 8
           LDAVSF
Sbjct: 663 LDAVSF 668
>NP_001269307
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDAVSF 8
           LDAVSF
Sbjct: 579 LDAVSF 584
>NP_001243528
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDAVSF 8
           LDAVSF
Sbjct: 682 LDAVSF 687
>NP_001243530
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDAVSF 8
           LDAVSF
Sbjct: 692 LDAVSF 697
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.124    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 313,824
Number of extensions: 322
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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