Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     869
NP_000242                                                              19     869
XP_005264389                                                           19     869
NP_689571                                                              17    3301
XP_006723071                                                           17    3301
XP_006723070                                                           17    3301
NP_003986                                                              17    4312
XP_005251536                                                           17    4312
XP_006716841                                                           17    4312
XP_005251535                                                           17    4312
NP_997229                                                              16    7355
XP_003960787                                                           16    7355
XP_003118801                                                           16    7355
XP_003119723                                                           16    7355
NP_001159906                                                           15    9605
NP_002206                                                              15    9605
NP_055452                                                              15    9605
NP_001139311                                                           15    9605
XP_005251384                                                           15    9605
XP_006716547                                                           15    9605
XP_006710602                                                           15    9605
XP_006710601                                                           15    9605
XP_006710598                                                           15    9605
XP_006710597                                                           15    9605
XP_006710596                                                           15    9605
XP_006710595                                                           15    9605
XP_006710594                                                           15    9605
XP_006710593                                                           15    9605
XP_006710592                                                           15    9605
XP_006710591                                                           15    9605
XP_006710590                                                           15    9605
XP_006710589                                                           15    9605
XP_006710588                                                           15    9605
XP_006710586                                                           15    9605
XP_006710585                                                           15    9605
XP_005270755                                                           15    9605
XP_006710584                                                           15    9605
XP_005270754                                                           15    9605
XP_005270753                                                           15    9605
XP_006710583                                                           15    9605
XP_005270752                                                           15    9605
XP_006710582                                                           15    9605
XP_005270751                                                           15    9605
NP_001139310                                                           15    9605
NP_001004690                                                           15    9605
>NP_001245210
          Length = 868

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           AQLDAV SF
Sbjct: 534 AQLDAVVSF 542
>NP_000242
          Length = 934

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           AQLDAV SF
Sbjct: 600 AQLDAVVSF 608
>XP_005264389
          Length = 921

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           AQLDAV SF
Sbjct: 600 AQLDAVVSF 608
>NP_689571
          Length = 221

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QLDAVASF 9
          QLD VASF
Sbjct: 81 QLDLVASF 88
>XP_006723071
          Length = 214

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QLDAVASF 9
          QLD VASF
Sbjct: 81 QLDLVASF 88
>XP_006723070
          Length = 246

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  QLDAVASF 9
          QLD VASF
Sbjct: 81 QLDLVASF 88
>NP_003986
          Length = 1047

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           A LDAV+SF
Sbjct: 936 ALLDAVSSF 944
>XP_005251536
          Length = 721

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           A LDAV+SF
Sbjct: 610 ALLDAVSSF 618
>XP_006716841
          Length = 1026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           A LDAV+SF
Sbjct: 915 ALLDAVSSF 923
>XP_005251535
          Length = 1050

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           A LDAV+SF
Sbjct: 939 ALLDAVSSF 947
>NP_997229
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLDAVASF 9
           Q DAVA+F
Sbjct: 454 QADAVATF 461
>XP_003960787
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDAVASF 9
           LDAVA+F
Sbjct: 511 LDAVAAF 517
>XP_003118801
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDAVASF 9
           LDAVA+F
Sbjct: 511 LDAVAAF 517
>XP_003119723
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDAVASF 9
           LDAVA+F
Sbjct: 511 LDAVAAF 517
>NP_001159906
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AQLDAVASF 9
          ++LDA ASF
Sbjct: 61 SKLDAQASF 69
>NP_002206
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           ++LDA ASF
Sbjct: 203 SKLDAQASF 211
>NP_055452
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DAVASF 9
          DAVASF
Sbjct: 71 DAVASF 76
>NP_001139311
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DAVASF 9
          DAVASF
Sbjct: 71 DAVASF 76
>XP_005251384
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DAVASF 9
          DAVASF
Sbjct: 58 DAVASF 63
>XP_006716547
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DAVASF 9
          DAVASF
Sbjct: 71 DAVASF 76
>XP_006710602
          Length = 7391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3543 AQLDALA 3549
>XP_006710601
          Length = 4720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710598
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3533 AQLDALA 3539
>XP_006710597
          Length = 7451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3543 AQLDALA 3549
>XP_006710596
          Length = 7512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3492 AQLDALA 3498
>XP_006710595
          Length = 7526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3506 AQLDALA 3512
>XP_006710594
          Length = 7528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3508 AQLDALA 3514
>XP_006710593
          Length = 7539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3519 AQLDALA 3525
>XP_006710592
          Length = 7544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3524 AQLDALA 3530
>XP_006710591
          Length = 7558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3538 AQLDALA 3544
>XP_006710590
          Length = 7563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3543 AQLDALA 3549
>XP_006710589
          Length = 7595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3575 AQLDALA 3581
>XP_006710588
          Length = 7614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710586
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710585
          Length = 7657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270755
          Length = 7663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710584
          Length = 7686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270754
          Length = 7694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270753
          Length = 7700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710583
          Length = 7702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270752
          Length = 7717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_006710582
          Length = 7720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>XP_005270751
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQLDAVA 7
            AQLDA+A
Sbjct: 3703 AQLDALA 3709
>NP_001139310
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DAVASF 9
          DAVASF
Sbjct: 38 DAVASF 43
>NP_001004690
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLDAVASF 9
           A +DAVA+F
Sbjct: 156 AIIDAVATF 164
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.124    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,690
Number of extensions: 315
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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