Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1935
NP_653080                                                              18    1935
XP_005267292                                                           18    1935
XP_005267291                                                           18    1935
XP_005267290                                                           18    1935
NP_060546                                                              17    4312
NP_001276949                                                           17    4312
XP_006726576                                                           17    4312
XP_006717607                                                           17    4312
XP_005252542                                                           17    4312
XP_006717518                                                           17    4312
XP_006717517                                                           17    4312
XP_006709998                                                           17    4312
NP_037528                                                              16    7355
NP_001269970                                                           16    7355
NP_001269971                                                           16    7355
XP_005261006                                                           16    7355
XP_006724055                                                           16    7355
NP_056471                                                              16    7355
NP_005870                                                              15    9605
>NP_005091
          Length = 1782

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQ AQKSAE
Sbjct: 862 AQQAQKSAE 870
>NP_653080
          Length = 1684

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQ AQKSAE
Sbjct: 764 AQQAQKSAE 772
>XP_005267292
          Length = 1677

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQ AQKSAE
Sbjct: 757 AQQAQKSAE 765
>XP_005267291
          Length = 1684

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQ AQKSAE
Sbjct: 764 AQQAQKSAE 772
>XP_005267290
          Length = 1782

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQ AQKSAE
Sbjct: 862 AQQAQKSAE 870
>NP_060546
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 409 AQLLRKSAE 417
>NP_001276949
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 409 AQLLRKSAE 417
>XP_006726576
          Length = 213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 127 AQLLRKSAE 135
>XP_006717607
          Length = 213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 127 AQLLRKSAE 135
>XP_005252542
          Length = 736

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 101 AQLLRKSAE 109
>XP_006717518
          Length = 736

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 101 AQLLRKSAE 109
>XP_006717517
          Length = 927

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQL +KSAE
Sbjct: 292 AQLLRKSAE 300
>XP_006709998
          Length = 187

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AQLAQKSAE 9
          AQL +KSAE
Sbjct: 71 AQLLRKSAE 79
>NP_037528
          Length = 1055

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQLAQK+ +
Sbjct: 705 AQLAQKALQ 713
>NP_001269970
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQLAQK+ +
Sbjct: 705 AQLAQKALQ 713
>NP_001269971
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQLAQK+ +
Sbjct: 705 AQLAQKALQ 713
>XP_005261006
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQLAQK+ +
Sbjct: 301 AQLAQKALQ 309
>XP_006724055
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQLAQK+ +
Sbjct: 406 AQLAQKALQ 414
>NP_056471
          Length = 1882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLAQKSAE 9
           AQ AQ+SAE
Sbjct: 381 AQGAQRSAE 389
>NP_005870
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AQLAQKSAE 9
          AQL+QK  E
Sbjct: 88 AQLSQKDKE 96
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288   0.0969    0.204 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 204,449
Number of extensions: 188
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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