Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055726                                                              20     509
NP_001071087                                                           17    2528
NP_002693                                                              17    3301
NP_001274456                                                           17    4312
NP_078968                                                              17    4312
NP_851320                                                              17    4312
XP_006712168                                                           17    4312
XP_005264621                                                           17    4312
XP_005264620                                                           17    4312
XP_006712167                                                           17    4312
XP_005264619                                                           17    4312
NP_001274457                                                           17    4312
NP_001001924                                                           16    5631
NP_001001925                                                           16    5631
XP_005273640                                                           16    5631
XP_005273639                                                           16    5631
XP_005273638                                                           16    5631
XP_005273637                                                           16    5631
XP_005273636                                                           16    5631
XP_005273635                                                           16    5631
XP_005273634                                                           16    5631
NP_002560                                                              16    7355
NP_001276753                                                           16    7355
NP_001276752                                                           16    7355
NP_001193665                                                           16    7355
NP_061327                                                              16    7355
NP_057227                                                              16    7355
NP_115655                                                              16    7355
XP_006723657                                                           16    7355
XP_006723656                                                           16    7355
XP_006723655                                                           16    7355
XP_006723654                                                           16    7355
XP_005259081                                                           16    7355
XP_006723314                                                           16    7355
XP_005259080                                                           16    7355
XP_006723313                                                           16    7355
XP_005247886                                                           16    7355
XP_006713849                                                           16    7355
NP_001138467                                                           16    7355
NP_037518                                                              15    9605
NP_998816                                                              15    9605
NP_653299                                                              15    9605
NP_001267728                                                           15    9605
NP_640337                                                              15    9605
NP_001121187                                                           15    9605
NP_001137236                                                           15    9605
NP_001137235                                                           15    9605
NP_570140                                                              15    9605
XP_005269867                                                           15    9605
XP_006715402                                                           15    9605
XP_006714342                                                           15    9605
XP_005263203                                                           15    9605
XP_005263202                                                           15    9605
XP_005263201                                                           15    9605
XP_005263200                                                           15    9605
XP_006710833                                                           15    9605
XP_006710832                                                           15    9605
NP_061174                                                              15    9605
NP_064611                                                              15    9605
NP_001092873                                                           15    9605
>NP_055726
          Length = 961

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QGQKVGSL 9
           QGQKVGSL
Sbjct: 612 QGQKVGSL 619
>NP_001071087
          Length = 331

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QGQKVGSL 9
           +GQK+GSL
Sbjct: 218 EGQKLGSL 225
>NP_002693
          Length = 301

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AQGQKVGSL 9
          AQGQ +G+L
Sbjct: 12 AQGQVIGTL 20
>NP_001274456
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>NP_078968
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>NP_851320
          Length = 440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  AQGQKVG 7
          AQGQ++G
Sbjct: 37 AQGQRIG 43
>XP_006712168
          Length = 596

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>XP_005264621
          Length = 687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 275 GQKVGTL 281
>XP_005264620
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>XP_006712167
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>XP_005264619
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>NP_001274457
          Length = 599

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQKVG+L
Sbjct: 293 GQKVGTL 299
>NP_001001924
          Length = 1270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>NP_001001925
          Length = 1216

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273640
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273639
          Length = 1216

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273638
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273637
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273636
          Length = 1270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273635
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>XP_005273634
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GQKVGS 8
           GQKVGS
Sbjct: 402 GQKVGS 407
>NP_002560
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AQGQKV 6
          AQGQKV
Sbjct: 24 AQGQKV 29
>NP_001276753
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AQGQKV 6
          AQGQKV
Sbjct: 24 AQGQKV 29
>NP_001276752
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AQGQKV 6
          AQGQKV
Sbjct: 24 AQGQKV 29
>NP_001193665
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 258 EGQKLGS 264
>NP_061327
          Length = 339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 225 EGQKLGS 231
>NP_057227
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 256 EGQKLGS 262
>NP_115655
          Length = 1196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QGQKVGSL 9
           Q QK+GSL
Sbjct: 146 QFQKIGSL 153
>XP_006723657
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 145 EGQKLGS 151
>XP_006723656
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 147 EGQKLGS 153
>XP_006723655
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 147 EGQKLGS 153
>XP_006723654
          Length = 285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+GS
Sbjct: 171 EGQKLGS 177
>XP_005259081
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QGQKVGSL 9
          +GQK G+L
Sbjct: 8  EGQKTGTL 15
>XP_006723314
          Length = 968

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QGQKVGSL 9
          +GQK G+L
Sbjct: 8  EGQKTGTL 15
>XP_005259080
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QGQKVGSL 9
          +GQK G+L
Sbjct: 8  EGQKTGTL 15
>XP_006723313
          Length = 1066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QGQKVGSL 9
          +GQK G+L
Sbjct: 8  EGQKTGTL 15
>XP_005247886
          Length = 1127

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QGQKVGSL 9
           Q QK+GSL
Sbjct: 146 QFQKIGSL 153
>XP_006713849
          Length = 1147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QGQKVGSL 9
           Q QK+GSL
Sbjct: 97  QFQKIGSL 104
>NP_001138467
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  AQGQKVG 7
          A+G+KVG
Sbjct: 38 AEGEKVG 44
>NP_037518
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+G+
Sbjct: 282 EGQKIGT 288
>NP_998816
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   QGQKVGS 8
           +GQK+G+
Sbjct: 263 EGQKIGT 269
>NP_653299
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQGQKVGSL 9
           AQG+ +G+L
Sbjct: 591 AQGEPLGAL 599
>NP_001267728
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQGQKVGSL 9
           AQG+ +G+L
Sbjct: 501 AQGEPLGAL 509
>NP_640337
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QGQKVGSL 9
            +GQK+G L
Sbjct: 1075 RGQKLGDL 1082
>NP_001121187
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QGQKVGSL 9
            +GQK+G L
Sbjct: 1111 RGQKLGDL 1118
>NP_001137236
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QKVGSL 9
          QKVGSL
Sbjct: 44 QKVGSL 49
>NP_001137235
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QKVGSL 9
          QKVGSL
Sbjct: 44 QKVGSL 49
>NP_570140
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QKVGSL 9
          QKVGSL
Sbjct: 8  QKVGSL 13
>XP_005269867
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  QGQKVGSL 9
          QG K GSL
Sbjct: 10 QGHKSGSL 17
>XP_006715402
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QGQKVGSL 9
            +GQK+G L
Sbjct: 1095 RGQKLGDL 1102
>XP_006714342
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 518 GQKLGAL 524
>XP_005263203
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 517 GQKLGAL 523
>XP_005263202
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 518 GQKLGAL 524
>XP_005263201
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 518 GQKLGAL 524
>XP_005263200
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 701 GQKLGAL 707
>XP_006710833
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QGQKVGSL 9
           +GQK G L
Sbjct: 196 EGQKAGEL 203
>XP_006710832
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QGQKVGSL 9
           +GQK G L
Sbjct: 196 EGQKAGEL 203
>NP_061174
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QGQKVGSL 9
           +GQK G L
Sbjct: 196 EGQKAGEL 203
>NP_064611
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 517 GQKLGAL 523
>NP_001092873
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GQKVGSL 9
           GQK+G+L
Sbjct: 517 GQKLGAL 523
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.124    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 632,947
Number of extensions: 1498
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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