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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_116207                                                              16    5631
NP_945352                                                              16    5631
XP_005266141                                                           16    5631
NP_848638                                                              16    7355
NP_055633                                                              16    7355
NP_004090                                                              16    7355
XP_005277842                                                           16    7355
XP_006718461                                                           16    7355
XP_006718460                                                           16    7355
NP_004623                                                              15    9605
NP_001186779                                                           15    9605
NP_001186778                                                           15    9605
NP_387506                                                              15    9605
NP_057332                                                              15    9605
NP_001129941                                                           15    9605
NP_076432                                                              15    9605
XP_005272546                                                           15    9605
XP_006722863                                                           15    9605
XP_005266307                                                           15    9605
XP_005266306                                                           15    9605
XP_005266305                                                           15    9605
XP_005266304                                                           15    9605
XP_005247785                                                           15    9605
XP_005247784                                                           15    9605
XP_005247783                                                           15    9605
XP_005247782                                                           15    9605
XP_005245537                                                           15    9605
XP_006711590                                                           15    9605

>NP_116207
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  PVQSQRA 8
          PVQ QRA
Sbjct: 11 PVQEQRA 17



>NP_945352
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   APVQSQRA 8
           AP+Q+Q+A
Sbjct: 116 APIQNQQA 123



>XP_005266141
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   APVQSQRA 8
           AP+Q+Q+A
Sbjct: 116 APIQNQQA 123



>NP_848638
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  APVQSQ 6
          APVQSQ
Sbjct: 22 APVQSQ 27



>NP_055633
          Length = 1216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   APVQSQ 6
           APVQSQ
Sbjct: 559 APVQSQ 564



>NP_004090
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PVQSQRAV 9
           PVQ QRA+
Sbjct: 200 PVQLQRAM 207



>XP_005277842
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   APVQSQ 6
           APVQSQ
Sbjct: 95  APVQSQ 100



>XP_006718461
          Length = 1247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   APVQSQ 6
           APVQSQ
Sbjct: 559 APVQSQ 564



>XP_006718460
          Length = 1392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   APVQSQ 6
           APVQSQ
Sbjct: 704 APVQSQ 709



>NP_004623
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PVQSQRAV 9
          PV+S RA+
Sbjct: 41 PVESPRAI 48



>NP_001186779
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PVQSQRAV 9
          PV+S RA+
Sbjct: 41 PVESPRAI 48



>NP_001186778
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PVQSQRAV 9
          PV+S RA+
Sbjct: 41 PVESPRAI 48



>NP_387506
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PVQSQRAV 9
          PV+S RA+
Sbjct: 41 PVESPRAI 48



>NP_057332
          Length = 1901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    VQSQRAV 9
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241



>NP_001129941
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   APVQSQR 7
           APV SQR
Sbjct: 313 APVPSQR 319



>NP_076432
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   APVQSQR 7
           APV SQR
Sbjct: 313 APVPSQR 319



>XP_005272546
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  APVQSQRA 8
          AP  SQRA
Sbjct: 50 APAPSQRA 57



>XP_006722863
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  APVQSQRA 8
          AP  SQRA
Sbjct: 50 APAPSQRA 57



>XP_005266307
          Length = 1796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    VQSQRAV 9
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241



>XP_005266306
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    VQSQRAV 9
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241



>XP_005266305
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    VQSQRAV 9
            VQSQR+V
Sbjct: 1190 VQSQRSV 1196



>XP_005266304
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    VQSQRAV 9
            VQSQR+V
Sbjct: 1235 VQSQRSV 1241



>XP_005247785
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   APVQSQR 7
           APV SQR
Sbjct: 313 APVPSQR 319



>XP_005247784
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   APVQSQR 7
           APV SQR
Sbjct: 307 APVPSQR 313



>XP_005247783
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   APVQSQR 7
           APV SQR
Sbjct: 313 APVPSQR 319



>XP_005247782
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   APVQSQR 7
           APV SQR
Sbjct: 313 APVPSQR 319



>XP_005245537
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PVQSQRAV 9
          PV+S RA+
Sbjct: 41 PVESPRAI 48



>XP_006711590
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PVQSQRAV 9
          PV+S RA+
Sbjct: 41 PVESPRAI 48



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.115    0.293 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 442,024
Number of extensions: 705
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)