Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_542782                                                              17    4312
NP_056093                                                              16    5631
NP_705618                                                              16    5631
NP_004289                                                              16    5631
NP_001265241                                                           16    5631
NP_001013649                                                           16    5631
XP_006724707                                                           16    5631
XP_005266932                                                           16    5631
XP_006715469                                                           16    5631
XP_005266931                                                           16    5631
NP_001029031                                                           16    7355
NP_001257377                                                           16    7355
NP_000009                                                              16    7355
NP_001193980                                                           16    7355
NP_057315                                                              16    7355
NP_001888                                                              16    7355
NP_958505                                                              16    7355
NP_001257376                                                           16    7355
NP_036266                                                              16    7355
NP_002716                                                              16    7355
XP_005258045                                                           16    7355
XP_006721579                                                           16    7355
XP_006712444                                                           16    7355
XP_006712442                                                           16    7355
XP_006712439                                                           16    7355
NP_001009899                                                           15    9605
NP_000032                                                              15    9605
NP_079170                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_037407                                                              15    9605
NP_001248323                                                           15    9605
NP_596870                                                              15    9605
NP_001243779                                                           15    9605
NP_001248321                                                           15    9605
NP_596869                                                              15    9605
NP_001243112                                                           15    9605
NP_001243111                                                           15    9605
NP_064581                                                              15    9605
NP_061956                                                              15    9605
NP_001034485                                                           15    9605
XP_005275322                                                           15    9605
XP_005275194                                                           15    9605
XP_005275048                                                           15    9605
XP_005275047                                                           15    9605
XP_005275045                                                           15    9605
XP_005275044                                                           15    9605
XP_006725765                                                           15    9605
XP_005272893                                                           15    9605
XP_005272892                                                           15    9605
XP_005272890                                                           15    9605
XP_005272889                                                           15    9605
XP_006725551                                                           15    9605
XP_005258924                                                           15    9605
XP_006721247                                                           15    9605
XP_006721246                                                           15    9605
XP_006721245                                                           15    9605
XP_006721244                                                           15    9605
XP_005247266                                                           15    9605
XP_005247265                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_005271003                                                           15    9605
XP_005271002                                                           15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_542782
          Length = 575

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ANLDQGRV 8
           ANL QGRV
Sbjct: 195 ANLCQGRV 202
>NP_056093
          Length = 1247

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ANLDQGRVR 9
            AN+DQ RV+
Sbjct: 1143 ANMDQIRVK 1151
>NP_705618
          Length = 1391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ANLDQGRVR 9
            A +DQ RVR
Sbjct: 1068 AKVDQNRVR 1076
>NP_004289
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ANLDQGRVR 9
            A +DQ RVR
Sbjct: 1009 AKVDQNRVR 1017
>NP_001265241
          Length = 1327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ANLDQGRVR 9
            A +DQ RVR
Sbjct: 1004 AKVDQNRVR 1012
>NP_001013649
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ANLDQGR 7
            ANLD GR
Sbjct: 1166 ANLDAGR 1172
>XP_006724707
          Length = 1337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ANLDQGR 7
            ANLD GR
Sbjct: 1278 ANLDAGR 1284
>XP_005266932
          Length = 1008

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ANLDQGRVR 9
           AN+DQ RV+
Sbjct: 904 ANMDQIRVK 912
>XP_006715469
          Length = 1235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ANLDQGRVR 9
            AN+DQ RV+
Sbjct: 1131 ANMDQIRVK 1139
>XP_005266931
          Length = 1283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ANLDQGRVR 9
            AN+DQ RV+
Sbjct: 1179 ANMDQIRVK 1187
>NP_001029031
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANLDQG 6
           AN+DQG
Sbjct: 380 ANMDQG 385
>NP_001257377
          Length = 579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANLDQG 6
           AN+DQG
Sbjct: 326 ANMDQG 331
>NP_000009
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANLDQG 6
           AN+DQG
Sbjct: 402 ANMDQG 407
>NP_001193980
          Length = 1477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LDQGRVR 9
           LD GR+R
Sbjct: 651 LDSGRIR 657
>NP_057315
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           LD+GR+R
Sbjct: 427 LDEGRLR 433
>NP_001888
          Length = 2322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NLDQGRVR 9
           +++QGRVR
Sbjct: 735 DVEQGRVR 742
>NP_958505
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NLDQGRVR 9
           NLD  R+R
Sbjct: 132 NLDNNRIR 139
>NP_001257376
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANLDQG 6
           AN+DQG
Sbjct: 425 ANMDQG 430
>NP_036266
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           +D+GRVR
Sbjct: 158 IDKGRVR 164
>NP_002716
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NLDQGRVR 9
           NLD  R+R
Sbjct: 132 NLDNNRIR 139
>XP_005258045
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           LD+GR+R
Sbjct: 398 LDEGRLR 404
>XP_006721579
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANLDQG 6
           AN+DQG
Sbjct: 448 ANMDQG 453
>XP_006712444
          Length = 1470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LDQGRVR 9
           LD GR+R
Sbjct: 651 LDSGRIR 657
>XP_006712442
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LDQGRVR 9
           LD GR+R
Sbjct: 651 LDSGRIR 657
>XP_006712439
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LDQGRVR 9
           LD GR+R
Sbjct: 651 LDSGRIR 657
>NP_001009899
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NLDQGRV 8
            NL++GRV
Sbjct: 1145 NLEKGRV 1151
>NP_000032
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           ++QGRVR
Sbjct: 203 VEQGRVR 209
>NP_079170
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NLDQGR 7
           NL+QGR
Sbjct: 162 NLEQGR 167
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 661 AAVDQARVR 669
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 661 AAVDQARVR 669
>NP_037407
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ANLDQGR 7
            A+LDQG+
Sbjct: 1078 ASLDQGK 1084
>NP_001248323
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NLDQGR 7
           NL+QGR
Sbjct: 162 NLEQGR 167
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 707 AAVDQARVR 715
>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 707 AAVDQARVR 715
>NP_001248321
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NLDQGR 7
           NL+QGR
Sbjct: 136 NLEQGR 141
>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 707 AAVDQARVR 715
>NP_001243112
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ANLDQGR 7
            A+LDQG+
Sbjct: 1078 ASLDQGK 1084
>NP_001243111
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ANLDQGR 7
            A+LDQG+
Sbjct: 1078 ASLDQGK 1084
>NP_064581
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDQGRV 8
           +DQGRV
Sbjct: 121 MDQGRV 126
>NP_061956
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           +DQGR++
Sbjct: 435 IDQGRIQ 441
>NP_001034485
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  NLDQGRV 8
          N+D GRV
Sbjct: 56 NVDMGRV 62
>XP_005275322
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005275194
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005275048
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005275047
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005275045
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005275044
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_006725765
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005272893
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005272892
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005272890
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005272889
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_006725551
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLDQGRVR 9
           NL++GR R
Sbjct: 159 NLEEGRQR 166
>XP_005258924
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           ++QGRVR
Sbjct: 229 VEQGRVR 235
>XP_006721247
          Length = 2564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ANLDQGR 7
           A+LDQG+
Sbjct: 979 ASLDQGK 985
>XP_006721246
          Length = 2620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ANLDQGR 7
            A+LDQG+
Sbjct: 1035 ASLDQGK 1041
>XP_006721245
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ANLDQGR 7
            A+LDQG+
Sbjct: 1044 ASLDQGK 1050
>XP_006721244
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ANLDQGR 7
            A+LDQG+
Sbjct: 1044 ASLDQGK 1050
>XP_005247266
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NLDQGRV 8
            NL++GRV
Sbjct: 1089 NLEKGRV 1095
>XP_005247265
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NLDQGRV 8
            NL++GRV
Sbjct: 1111 NLEKGRV 1117
>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 708 AAVDQARVR 716
>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 708 AAVDQARVR 716
>XP_005271003
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           +DQGR++
Sbjct: 294 IDQGRIQ 300
>XP_005271002
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LDQGRVR 9
           +DQGR++
Sbjct: 421 IDQGRIQ 427
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 707 AAVDQARVR 715
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANLDQGRVR 9
           A +DQ RVR
Sbjct: 661 AAVDQARVR 669
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.137    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 608,057
Number of extensions: 732
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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