Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_000188                                                              16    5631
XP_005252027                                                           16    5631
XP_006717157                                                           16    5631
NP_001162625                                                           16    7355
NP_775765                                                              16    7355
NP_001122400                                                           15    9605
NP_001243465                                                           15    9605
NP_062828                                                              15    9605
XP_006719049                                                           15    9605
XP_005246589                                                           15    9605
XP_006712561                                                           15    9605
NP_002185                                                              15    9605
NP_036510                                                              15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1148 AMSNLLNAN 1156
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1148 AMSNLLNAN 1156
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1158 AMSNLLNAN 1166
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1158 AMSNLLNAN 1166
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1158 AMSNLLNAN 1166
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1148 AMSNLLNAN 1156
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1158 AMSNLLNAN 1166
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1158 AMSNLLNAN 1166
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1145 AMSNLLNAN 1153
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1148 AMSNLLNAN 1156
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AMSKLLNAN 9
            AMS LLNAN
Sbjct: 1158 AMSNLLNAN 1166
>NP_000188
          Length = 310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AMSKLLNAN 9
           AM+K LN N
Sbjct: 234 AMTKYLNTN 242
>XP_005252027
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AMSKLLNAN 9
           AM+K LN N
Sbjct: 114 AMTKYLNTN 122
>XP_006717157
          Length = 256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AMSKLLNAN 9
           AM+K LN N
Sbjct: 180 AMTKYLNTN 188
>NP_001162625
          Length = 214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AMSKLLN 7
          A+SKLLN
Sbjct: 34 ALSKLLN 40
>NP_775765
          Length = 214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AMSKLLN 7
          A+SKLLN
Sbjct: 34 ALSKLLN 40
>NP_001122400
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSKLLNAN 9
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>NP_001243465
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  MSKLLN 7
          MSKLLN
Sbjct: 52 MSKLLN 57
>NP_062828
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  MSKLLN 7
          MSKLLN
Sbjct: 61 MSKLLN 66
>XP_006719049
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 MSKLLN 7
         MSKLLN
Sbjct: 1 MSKLLN 6
>XP_005246589
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSKLLNAN 9
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>XP_006712561
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSKLLNAN 9
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>NP_002185
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSKLLNAN 9
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>NP_036510
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AMSKLLNAN 9
           A+ K+LN N
Sbjct: 300 ALKKILNKN 308
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.113    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 311,748
Number of extensions: 387
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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