Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
NP_001002811                                                           18    1135
NP_001002812                                                           18    1135
XP_006711719                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711712                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_006711707                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
NP_036423                                                              17    3301
XP_006719768                                                           17    3301
NP_001273763                                                           17    4312
NP_002927                                                              17    4312
NP_001273766                                                           17    4312
NP_056240                                                              16    5631
XP_006712046                                                           16    5631
NP_002408                                                              16    7355
NP_001139438                                                           16    7355
NP_006382                                                              16    7355
NP_001099038                                                           16    7355
NP_001099037                                                           16    7355
NP_001099036                                                           16    7355
NP_071396                                                              16    7355
NP_003651                                                              16    7355
XP_006726477                                                           16    7355
XP_006726476                                                           16    7355
XP_003960392                                                           16    7355
XP_006723513                                                           16    7355
XP_006717927                                                           16    7355
XP_006715230                                                           16    7355
XP_006715229                                                           16    7355
XP_005249350                                                           16    7355
XP_005249349                                                           16    7355
XP_005249348                                                           16    7355
XP_005249347                                                           16    7355
XP_005249346                                                           16    7355
XP_006714494                                                           16    7355
XP_006714493                                                           16    7355
XP_373030                                                              16    7355
XP_006710222                                                           16    7355
XP_006710221                                                           16    7355
XP_001717475                                                           16    7355
NP_001269557                                                           15    9605
NP_001269560                                                           15    9605
NP_000038                                                              15    9605
NP_057726                                                              15    9605
XP_005274578                                                           15    9605
XP_005274576                                                           15    9605
XP_005274575                                                           15    9605
XP_005254495                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 892 AMERLTQEV 900
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 826 AMERLTQEV 834
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 826 AMERLTQEV 834
>NP_001002811
          Length = 1132

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>NP_001002812
          Length = 969

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 826 AMERLTQEV 834
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 892 AMERLTQEV 900
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 892 AMERLTQEV 900
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 892 AMERLTQEV 900
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 826 AMERLTQEV 834
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 826 AMERLTQEV 834
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 829 AMERLTQEV 837
>XP_006711712
          Length = 2473

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 892 AMERLTQEV 900
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 892 AMERLTQEV 900
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_006711707
          Length = 2553

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           AMERLTQ V
Sbjct: 989 AMERLTQEV 997
>NP_036423
          Length = 2120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A ERLTQA+
Sbjct: 1194 AAERLTQAL 1202
>XP_006719768
          Length = 2120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A ERLTQA+
Sbjct: 1194 AAERLTQAL 1202
>NP_001273763
          Length = 260

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           A+ERLTQ +
Sbjct: 220 ALERLTQGM 228
>NP_002927
          Length = 286

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           A+ERLTQ +
Sbjct: 246 ALERLTQGM 254
>NP_001273766
          Length = 169

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           A+ERLTQ +
Sbjct: 129 ALERLTQGM 137
>NP_056240
          Length = 1720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AMERLTQAV 9
            AMER  QAV
Sbjct: 1497 AMERRVQAV 1505
>XP_006712046
          Length = 1612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AMERLTQAV 9
            AMER  QAV
Sbjct: 1389 AMERRVQAV 1397
>NP_002408
          Length = 3256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AMERLTQ 7
            A+ERLTQ
Sbjct: 2618 AVERLTQ 2624
>NP_001139438
          Length = 2896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AMERLTQ 7
            A+ERLTQ
Sbjct: 2258 AVERLTQ 2264
>NP_006382
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AMERLTQAV 9
           A+ERLT+ V
Sbjct: 765 ALERLTREV 773
>NP_001099038
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1345 SLERLRQAV 1353
>NP_001099037
          Length = 1757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1345 SLERLRQAV 1353
>NP_001099036
          Length = 1770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1358 SLERLRQAV 1366
>NP_071396
          Length = 1805

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1358 SLERLRQAV 1366
>NP_003651
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MERLTQAV 9
           +ER+TQA+
Sbjct: 724 LERMTQAL 731
>XP_006726477
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1253 ALEKLTAAV 1261
>XP_006726476
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1253 ALEKLTAAV 1261
>XP_003960392
          Length = 1826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1286 ALEKLTAAV 1294
>XP_006723513
          Length = 1185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MERLTQAV 9
           +ER+TQA+
Sbjct: 724 LERMTQAL 731
>XP_006717927
          Length = 2406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AMERLTQ 7
            A+ERLTQ
Sbjct: 1768 AVERLTQ 1774
>XP_006715230
          Length = 1734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1287 SLERLRQAV 1295
>XP_006715229
          Length = 1782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1335 SLERLRQAV 1343
>XP_005249350
          Length = 1810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1398 SLERLRQAV 1406
>XP_005249349
          Length = 1824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1398 SLERLRQAV 1406
>XP_005249348
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1385 SLERLRQAV 1393
>XP_005249347
          Length = 1837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1398 SLERLRQAV 1406
>XP_005249346
          Length = 1845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            ++ERL QAV
Sbjct: 1398 SLERLRQAV 1406
>XP_006714494
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1253 ALEKLTAAV 1261
>XP_006714493
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1253 ALEKLTAAV 1261
>XP_373030
          Length = 1826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1286 ALEKLTAAV 1294
>XP_006710222
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1253 ALEKLTAAV 1261
>XP_006710221
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1253 ALEKLTAAV 1261
>XP_001717475
          Length = 1826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AMERLTQAV 9
            A+E+LT AV
Sbjct: 1286 ALEKLTAAV 1294
>NP_001269557
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MERLTQAV 9
           MER+ QAV
Sbjct: 563 MERVQQAV 570
>NP_001269560
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MERLTQAV 9
           MER+ QAV
Sbjct: 493 MERVQQAV 500
>NP_000038
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MERLTQAV 9
           MER+ QAV
Sbjct: 538 MERVQQAV 545
>NP_057726
          Length = 3674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AMERLTQAV 9
            A ERL QA+
Sbjct: 3193 AWERLDQAI 3201
>XP_005274578
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MERLTQAV 9
           MER+ QAV
Sbjct: 484 MERVQQAV 491
>XP_005274576
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MERLTQAV 9
           MER+ QAV
Sbjct: 538 MERVQQAV 545
>XP_005274575
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MERLTQAV 9
           MER+ QAV
Sbjct: 547 MERVQQAV 554
>XP_005254495
          Length = 3694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AMERLTQAV 9
            A ERL QA+
Sbjct: 3213 AWERLDQAI 3221
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.120    0.279 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 340,683
Number of extensions: 380
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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