Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_009049                                                              16    5631
XP_006714558                                                           16    5631
NP_001269645                                                           16    7355
NP_036579                                                              16    7355
NP_001269646                                                           16    7355
NP_001269647                                                           16    7355
NP_065816                                                              16    7355
NP_056274                                                              16    7355
NP_001138397                                                           16    7355
NP_001171517                                                           16    7355
NP_002453                                                              16    7355
NP_001276977                                                           16    7355
NP_004742                                                              16    7355
XP_005261039                                                           16    7355
XP_005261038                                                           16    7355
XP_005261037                                                           16    7355
XP_005261036                                                           16    7355
XP_005261035                                                           16    7355
XP_006724068                                                           16    7355
XP_006718557                                                           16    7355
XP_005250173                                                           16    7355
XP_005265253                                                           16    7355
XP_006710573                                                           16    7355
XP_006710572                                                           16    7355
XP_006710571                                                           16    7355
XP_006710570                                                           16    7355
XP_006710569                                                           16    7355
XP_006710568                                                           16    7355
XP_006710567                                                           16    7355
XP_006710566                                                           16    7355
XP_005245859                                                           16    7355
NP_001087199                                                           16    7355
NP_886552                                                              16    7355
NP_001167540                                                           15    9605
NP_796372                                                              15    9605
NP_002936                                                              15    9605
NP_001171441                                                           15    9605
NP_444506                                                              15    9605
NP_001171442                                                           15    9605
NP_001171440                                                           15    9605
NP_004938                                                              15    9605
NP_001269789                                                           15    9605
NP_001269787                                                           15    9605
NP_001269790                                                           15    9605
NP_115878                                                              15    9605
NP_115668                                                              15    9605
NP_001269785                                                           15    9605
NP_001099147                                                           15    9605
XP_006721210                                                           15    9605
XP_006721208                                                           15    9605
XP_006713073                                                           15    9605
XP_005264975                                                           15    9605
XP_006713072                                                           15    9605
XP_006713071                                                           15    9605
XP_005264974                                                           15    9605
XP_005264973                                                           15    9605
XP_005264972                                                           15    9605
XP_005264971                                                           15    9605
XP_005264424                                                           15    9605
XP_005245341                                                           15    9605
XP_006711459                                                           15    9605
XP_005245340                                                           15    9605
XP_006711458                                                           15    9605
XP_006711457                                                           15    9605
XP_006711456                                                           15    9605
NP_006789                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MEELFQSS 9
            MEELFQSS
Sbjct: 1774 MEELFQSS 1781
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MEELFQSS 9
            MEELFQSS
Sbjct: 1774 MEELFQSS 1781
>NP_009049
          Length = 3097

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   MEELFQ 7
           MEELFQ
Sbjct: 771 MEELFQ 776
>XP_006714558
          Length = 2612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   MEELFQ 7
           MEELFQ
Sbjct: 286 MEELFQ 291
>NP_001269645
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           +EEL QSS
Sbjct: 682 LEELLQSS 689
>NP_036579
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           +EEL QSS
Sbjct: 682 LEELLQSS 689
>NP_001269646
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           +EEL QSS
Sbjct: 682 LEELLQSS 689
>NP_001269647
          Length = 1167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           +EEL QSS
Sbjct: 624 LEELLQSS 631
>NP_065816
          Length = 5183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>NP_056274
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           AM+E+FQ
Sbjct: 196 AMDEIFQ 202
>NP_001138397
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>NP_001171517
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>NP_002453
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>NP_001276977
          Length = 523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           AM+E+FQ
Sbjct: 178 AMDEIFQ 184
>NP_004742
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           ME+L QSS
Sbjct: 210 MEDLLQSS 217
>XP_005261039
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>XP_005261038
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>XP_005261037
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>XP_005261036
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>XP_005261035
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 573 SMEEIFQ 579
>XP_006724068
          Length = 685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           +MEE+FQ
Sbjct: 596 SMEEIFQ 602
>XP_006718557
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AMEELFQ 7
           AM+E+FQ
Sbjct: 196 AMDEIFQ 202
>XP_005250173
          Length = 1222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           +EEL QSS
Sbjct: 682 LEELLQSS 689
>XP_005265253
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  MEELFQSS 9
          M+E+FQS+
Sbjct: 89 MKEMFQSA 96
>XP_006710573
          Length = 5177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710572
          Length = 5188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710571
          Length = 5194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710570
          Length = 5195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710569
          Length = 5212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710568
          Length = 5221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710567
          Length = 5222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_006710566
          Length = 5222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>XP_005245859
          Length = 5223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    AMEELFQSS 9
            AMEE F  S
Sbjct: 1396 AMEEFFSDS 1404
>NP_001087199
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AMEELFQSS 9
          A++ELFQ +
Sbjct: 65 ALQELFQKA 73
>NP_886552
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  MEELFQSS 9
          M+E+FQS+
Sbjct: 89 MKEMFQSA 96
>NP_001167540
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MEELFQSS 9
          MEE FQS+
Sbjct: 7  MEENFQSA 14
>NP_796372
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MEELFQSS 9
          MEE FQS+
Sbjct: 7  MEENFQSA 14
>NP_002936
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AMEELFQSS 9
           A EE+FQ++
Sbjct: 557 AFEEVFQNA 565
>NP_001171441
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AMEELFQSS 9
           A+E+LF+ S
Sbjct: 560 ALEQLFKKS 568
>NP_444506
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AMEELFQSS 9
           A+E+LF+ S
Sbjct: 596 ALEQLFKKS 604
>NP_001171442
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AMEELFQSS 9
           A+E+LF+ S
Sbjct: 559 ALEQLFKKS 567
>NP_001171440
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AMEELFQSS 9
           A+E+LF+ S
Sbjct: 581 ALEQLFKKS 589
>NP_004938
          Length = 2030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>NP_001269789
          Length = 2241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>NP_001269787
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>NP_001269790
          Length = 1529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>NP_115878
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MEELFQSS 9
           +EEL QSS
Sbjct: 176 VEELLQSS 183
>NP_115668
          Length = 1529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>NP_001269785
          Length = 2241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>NP_001099147
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   MEELFQSS 9
           MEE  QSS
Sbjct: 299 MEEFIQSS 306
>XP_006721210
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 ELFQSS 9
         ELFQSS
Sbjct: 2 ELFQSS 7
>XP_006721208
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 ELFQSS 9
         ELFQSS
Sbjct: 2 ELFQSS 7
>XP_006713073
          Length = 1869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_005264975
          Length = 2022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_006713072
          Length = 2042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_006713071
          Length = 2050

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_005264974
          Length = 2057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_005264973
          Length = 2062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_005264972
          Length = 2065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_005264971
          Length = 2071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AMEELFQS 8
           +++ELFQS
Sbjct: 759 SIQELFQS 766
>XP_005264424
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AMEELFQSS 9
           A+E+LF+ S
Sbjct: 327 ALEQLFKKS 335
>XP_005245341
          Length = 2068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 418 MEELFET 424
>XP_006711459
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>XP_005245340
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>XP_006711458
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>XP_006711457
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>XP_006711456
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   MEELFQS 8
           MEELF++
Sbjct: 590 MEELFET 596
>NP_006789
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   MEELFQSS 9
           MEE  QSS
Sbjct: 290 MEEFIQSS 297
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.113    0.260 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 513,368
Number of extensions: 943
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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