Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              20     509
NP_005913                                                              20     509
XP_005267046                                                           20     509
XP_005267045                                                           20     509
NP_056121                                                              18    1935
NP_077288                                                              16    5631
NP_057006                                                              16    5631
NP_001123237                                                           16    5631
XP_006724887                                                           16    5631
XP_006719656                                                           16    5631
NP_000577                                                              16    7355
NP_065974                                                              16    7355
NP_001272478                                                           16    7355
NP_004810                                                              16    7355
NP_001254524                                                           16    7355
NP_001254523                                                           16    7355
XP_005259343                                                           16    7355
XP_006719425                                                           16    7355
XP_006719424                                                           16    7355
XP_006712721                                                           16    7355
XP_006712720                                                           16    7355
XP_006712719                                                           16    7355
XP_005246770                                                           16    7355
XP_005246768                                                           16    7355
XP_005246769                                                           16    7355
NP_001129575                                                           15    9605
NP_001545                                                              15    9605
NP_056327                                                              15    9605
NP_066934                                                              15    9605
NP_056366                                                              15    9605
NP_056003                                                              15    9605
NP_055987                                                              15    9605
NP_005081                                                              15    9605
NP_001185517                                                           15    9605
XP_006726572                                                           15    9605
XP_006726571                                                           15    9605
XP_006726570                                                           15    9605
XP_003960511                                                           15    9605
XP_006717795                                                           15    9605
XP_006717414                                                           15    9605
XP_006716942                                                           15    9605
XP_006716621                                                           15    9605
XP_005250973                                                           15    9605
XP_005250972                                                           15    9605
XP_006716620                                                           15    9605
XP_006716619                                                           15    9605
XP_006713959                                                           15    9605
XP_005248043                                                           15    9605
XP_006713958                                                           15    9605
XP_005265092                                                           15    9605
XP_005265091                                                           15    9605
XP_006713163                                                           15    9605
XP_005245087                                                           15    9605
XP_005245086                                                           15    9605
XP_005245085                                                           15    9605
XP_005245084                                                           15    9605
XP_006711302                                                           15    9605
XP_005245083                                                           15    9605
XP_005245082                                                           15    9605
XP_005245081                                                           15    9605
XP_005245080                                                           15    9605
XP_005245079                                                           15    9605
XP_005245077                                                           15    9605
XP_005245076                                                           15    9605
XP_006711301                                                           15    9605
XP_005245075                                                           15    9605
XP_005245074                                                           15    9605
XP_005245073                                                           15    9605
XP_005245072                                                           15    9605
XP_006710283                                                           15    9605
XP_006710282                                                           15    9605
NP_065824                                                              15    9605
NP_001106834                                                           15    9605
NP_001108105                                                           15    9605
NP_976324                                                              15    9605
NP_001106832                                                           15    9605
>NP_006715
          Length = 1558

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ALVTNDRPV 9
           ALV NDRPV
Sbjct: 560 ALVKNDRPV 568
>NP_005913
          Length = 1608

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ALVTNDRPV 9
           ALV NDRPV
Sbjct: 560 ALVKNDRPV 568
>XP_005267046
          Length = 1554

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ALVTNDRPV 9
           ALV NDRPV
Sbjct: 560 ALVKNDRPV 568
>XP_005267045
          Length = 1604

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ALVTNDRPV 9
           ALV NDRPV
Sbjct: 560 ALVKNDRPV 568
>NP_056121
          Length = 2620

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  ALVTNDRP 8
          AL+TN+RP
Sbjct: 39 ALLTNERP 46
>NP_077288
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALVTNDRPV 9
            +LVTN +PV
Sbjct: 1089 SLVTNCKPV 1097
>NP_057006
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +TND P+
Sbjct: 267 ITNDEPI 273
>NP_001123237
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +TND P+
Sbjct: 267 ITNDEPI 273
>XP_006724887
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +TND P+
Sbjct: 267 ITNDEPI 273
>XP_006719656
          Length = 1179

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALVTNDRPV 9
            +LVTN +PV
Sbjct: 1089 SLVTNCKPV 1097
>NP_000577
          Length = 153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ALVTNDRP 8
          ALVTN  P
Sbjct: 15 ALVTNSAP 22
>NP_065974
          Length = 2354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>NP_001272478
          Length = 2352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 193 SNDRPV 198
>NP_004810
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ALVTNDRPV 9
          AL+TND  +
Sbjct: 44 ALITNDSKI 52
>NP_001254524
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +T DRP+
Sbjct: 614 ITKDRPI 620
>NP_001254523
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +T DRP+
Sbjct: 614 ITKDRPI 620
>XP_005259343
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ALVTNDRPV 9
          AL+TND  +
Sbjct: 44 ALITNDSKI 52
>XP_006719425
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +T DRP+
Sbjct: 415 ITKDRPI 421
>XP_006719424
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   VTNDRPV 9
           +T DRP+
Sbjct: 646 ITKDRPI 652
>XP_006712721
          Length = 1206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>XP_006712720
          Length = 1991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>XP_006712719
          Length = 2354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>XP_005246770
          Length = 2354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>XP_005246768
          Length = 2354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>XP_005246769
          Length = 2354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNDRPV 9
           +NDRPV
Sbjct: 195 SNDRPV 200
>NP_001129575
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LVTNDRP 8
           +VTN RP
Sbjct: 547 IVTNKRP 553
>NP_001545
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   VTNDRP 8
           VTND P
Sbjct: 251 VTNDNP 256
>NP_056327
          Length = 4265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVTNDRPV 9
            L+TN +PV
Sbjct: 2216 LLTNKKPV 2223
>NP_066934
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALVTNDRPV 9
           A VTN +P+
Sbjct: 845 AKVTNKKPI 853
>NP_056366
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVTNDRPV 9
           LVT D+P+
Sbjct: 406 LVTPDQPI 413
>NP_056003
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ALVTNDRP 8
           AL+  DRP
Sbjct: 396 ALILEDRP 403
>NP_055987
          Length = 2817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1006 NDRPV 1010
>NP_005081
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LVTNDRPV 9
           LVT D PV
Sbjct: 316 LVTGDDPV 323
>NP_001185517
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LVTNDRPV 9
           LVT D PV
Sbjct: 316 LVTGDDPV 323
>XP_006726572
          Length = 2066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1166 NDRPV 1170
>XP_006726571
          Length = 3681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 2822 NDRPV 2826
>XP_006726570
          Length = 3722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 2822 NDRPV 2826
>XP_003960511
          Length = 3722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 2822 NDRPV 2826
>XP_006717795
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ALVTNDRP 8
           AL+  DRP
Sbjct: 489 ALILEDRP 496
>XP_006717414
          Length = 5100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 4200 NDRPV 4204
>XP_006716942
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALVTNDRPV 9
           A VTN +P+
Sbjct: 717 AKVTNKKPI 725
>XP_006716621
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NDRPV 9
           NDRPV
Sbjct: 987 NDRPV 991
>XP_005250973
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NDRPV 9
           NDRPV
Sbjct: 987 NDRPV 991
>XP_005250972
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NDRPV 9
           NDRPV
Sbjct: 987 NDRPV 991
>XP_006716620
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NDRPV 9
           NDRPV
Sbjct: 987 NDRPV 991
>XP_006716619
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NDRPV 9
           NDRPV
Sbjct: 987 NDRPV 991
>XP_006713959
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  ALVTNDRP 8
          AL+  DRP
Sbjct: 85 ALILEDRP 92
>XP_005248043
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ALVTNDRP 8
           AL+  DRP
Sbjct: 313 ALILEDRP 320
>XP_006713958
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ALVTNDRP 8
           AL+  DRP
Sbjct: 313 ALILEDRP 320
>XP_005265092
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVTNDRPV 9
           LVT D+P+
Sbjct: 228 LVTPDQPI 235
>XP_005265091
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVTNDRPV 9
           LVT D+P+
Sbjct: 343 LVTPDQPI 350
>XP_006713163
          Length = 4265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LVTNDRPV 9
            L+TN +PV
Sbjct: 2216 LLTNKKPV 2223
>XP_005245087
          Length = 2708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245086
          Length = 2714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245085
          Length = 2718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245084
          Length = 2719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_006711302
          Length = 2754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245083
          Length = 2774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245082
          Length = 2779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245081
          Length = 2819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245080
          Length = 2824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245079
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245077
          Length = 2858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245076
          Length = 2869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_006711301
          Length = 2896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1006 NDRPV 1010
>XP_005245075
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1003 NDRPV 1007
>XP_005245074
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_005245073
          Length = 2901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1006 NDRPV 1010
>XP_005245072
          Length = 2903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1008 NDRPV 1012
>XP_006710283
          Length = 2066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1166 NDRPV 1170
>XP_006710282
          Length = 2621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5    NDRPV 9
            NDRPV
Sbjct: 1721 NDRPV 1725
>NP_065824
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ALVTNDRP 8
           AL+  DRP
Sbjct: 313 ALILEDRP 320
>NP_001106834
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  ALVTNDRP 8
          AL+  DRP
Sbjct: 33 ALILEDRP 40
>NP_001108105
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  LVTNDRPV 9
          LVT D PV
Sbjct: 85 LVTGDDPV 92
>NP_976324
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NDRPV 9
           NDRPV
Sbjct: 987 NDRPV 991
>NP_001106832
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ALVTNDRP 8
           AL+  DRP
Sbjct: 313 ALILEDRP 320
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.133    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 656,216
Number of extensions: 965
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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