Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              19     665
XP_005251512                                                           19     665
NP_065974                                                              16    5631
NP_001272478                                                           16    5631
XP_006712720                                                           16    5631
XP_006712719                                                           16    5631
XP_005246770                                                           16    5631
XP_005246768                                                           16    5631
XP_005246769                                                           16    5631
NP_783864                                                              16    7355
NP_001269388                                                           16    7355
NP_689596                                                              16    7355
XP_006717524                                                           16    7355
XP_005252546                                                           16    7355
XP_006717523                                                           16    7355
XP_006717522                                                           16    7355
XP_006717521                                                           16    7355
XP_006717520                                                           16    7355
XP_005262701                                                           16    7355
NP_004278                                                              15    9605
NP_001012529                                                           15    9605
NP_473363                                                              15    9605
NP_001269836                                                           15    9605
NP_001269837                                                           15    9605
NP_001269838                                                           15    9605
NP_006576                                                              15    9605
XP_005257902                                                           15    9605
XP_005257901                                                           15    9605
XP_006722255                                                           15    9605
XP_006722254                                                           15    9605
XP_006722253                                                           15    9605
XP_006722252                                                           15    9605
XP_006722251                                                           15    9605
XP_005257900                                                           15    9605
>NP_004963
          Length = 1132

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ALRVDQIRN 9
            ALRVDQIR+
Sbjct: 1120 ALRVDQIRD 1128
>XP_005251512
          Length = 1132

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ALRVDQIRN 9
            ALRVDQIR+
Sbjct: 1120 ALRVDQIRD 1128
>NP_065974
          Length = 2354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1793 LKVDSVRN 1800
>NP_001272478
          Length = 2352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1791 LKVDSVRN 1798
>XP_006712720
          Length = 1991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1793 LKVDSVRN 1800
>XP_006712719
          Length = 2354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1793 LKVDSVRN 1800
>XP_005246770
          Length = 2354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1793 LKVDSVRN 1800
>XP_005246768
          Length = 2354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1793 LKVDSVRN 1800
>XP_005246769
          Length = 2354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LRVDQIRN 9
            L+VD +RN
Sbjct: 1793 LKVDSVRN 1800
>NP_783864
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ALRVDQIR 8
           A+R+D+IR
Sbjct: 446 AIRLDEIR 453
>NP_001269388
          Length = 328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ALRVDQIRN 9
           +L VD++RN
Sbjct: 278 SLMVDRVRN 286
>NP_689596
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ALRVDQIR 8
           ALR+DQ++
Sbjct: 548 ALRLDQLK 555
>XP_006717524
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ALRVDQIRN 9
          ALR  Q+RN
Sbjct: 21 ALRTCQVRN 29
>XP_005252546
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ALRVDQIRN 9
          ALR  Q+RN
Sbjct: 21 ALRTCQVRN 29
>XP_006717523
          Length = 1095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ALRVDQIRN 9
          ALR  Q+RN
Sbjct: 21 ALRTCQVRN 29
>XP_006717522
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ALRVDQIRN 9
          ALR  Q+RN
Sbjct: 21 ALRTCQVRN 29
>XP_006717521
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ALRVDQIRN 9
          ALR  Q+RN
Sbjct: 21 ALRTCQVRN 29
>XP_006717520
          Length = 1110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ALRVDQIRN 9
          ALR  Q+RN
Sbjct: 21 ALRTCQVRN 29
>XP_005262701
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ALRVDQIR 8
           A+R+D+IR
Sbjct: 446 AIRLDEIR 453
>NP_004278
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>NP_001012529
          Length = 195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>NP_473363
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>NP_001269836
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LRVDQI 7
           LRVDQI
Sbjct: 500 LRVDQI 505
>NP_001269837
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LRVDQI 7
           LRVDQI
Sbjct: 468 LRVDQI 473
>NP_001269838
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LRVDQI 7
           LRVDQI
Sbjct: 446 LRVDQI 451
>NP_006576
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LRVDQI 7
           LRVDQI
Sbjct: 519 LRVDQI 524
>XP_005257902
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 50 LRVDQLK 56
>XP_005257901
          Length = 165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>XP_006722255
          Length = 179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>XP_006722254
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>XP_006722253
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>XP_006722252
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
>XP_006722251
          Length = 239

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 50 LRVDQLK 56
>XP_005257900
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRVDQIR 8
          LRVDQ++
Sbjct: 68 LRVDQLK 74
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.141    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,287
Number of extensions: 457
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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