Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1135
NP_001075109                                                           18    1135
NP_001092757                                                           16    5631
NP_056998                                                              16    5631
NP_003310                                                              16    5631
NP_001165763                                                           16    5631
NP_597676                                                              16    5631
NP_001243779                                                           16    5631
NP_596869                                                              16    5631
NP_060023                                                              16    5631
NP_001171500                                                           16    5631
NP_001910                                                              16    5631
XP_005255403                                                           16    5631
XP_006716433                                                           16    5631
XP_005273633                                                           16    5631
XP_006716432                                                           16    5631
XP_005273632                                                           16    5631
XP_005246888                                                           16    5631
XP_006712788                                                           16    5631
XP_006712787                                                           16    5631
XP_006712786                                                           16    5631
NP_112561                                                              16    5631
NP_001254479                                                           16    5631
NP_597681                                                              16    5631
NP_005752                                                              16    7355
NP_001248385                                                           16    7355
NP_002339                                                              16    7355
NP_001028839                                                           16    7355
NP_001248386                                                           16    7355
XP_006719249                                                           16    7355
XP_006711388                                                           16    7355
XP_006711387                                                           16    7355
XP_006711386                                                           16    7355
XP_006711385                                                           16    7355
XP_006711384                                                           16    7355
XP_006711383                                                           16    7355
XP_005245221                                                           16    7355
NP_071405                                                              16    7355
NP_001257354                                                           15    9605
NP_003609                                                              15    9605
NP_060009                                                              15    9605
XP_006721125                                                           15    9605
XP_005245751                                                           15    9605
XP_005245750                                                           15    9605
XP_005277490                                                           15    9605
XP_005277491                                                           15    9605
XP_005277489                                                           15    9605
NP_612440                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ALQTSLVF 8
          ALQTSLVF
Sbjct: 52 ALQTSLVF 59
>NP_001075109
          Length = 4097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ALQTSLVF 8
          ALQTSLVF
Sbjct: 52 ALQTSLVF 59
>NP_001092757
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TSLVFP 9
           TSLVFP
Sbjct: 353 TSLVFP 358
>NP_056998
          Length = 958

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TSLVFP 9
           TSLVFP
Sbjct: 300 TSLVFP 305
>NP_003310
          Length = 26926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 24586 TSLVFP 24591
>NP_001165763
          Length = 447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TSLVFP 9
           TSLVFP
Sbjct: 334 TSLVFP 339
>NP_597676
          Length = 27051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 24711 TSLVFP 24716
>NP_001243779
          Length = 34350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 32010 TSLVFP 32015
>NP_596869
          Length = 33423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 31083 TSLVFP 31088
>NP_060023
          Length = 1556

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LQTSLVFP 9
            LQTSLV P
Sbjct: 1492 LQTSLVRP 1499
>NP_001171500
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ALQTSLVFP 9
           ALQ  L+FP
Sbjct: 188 ALQLGLLFP 196
>NP_001910
          Length = 302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ALQTSLVFP 9
           ALQ  L+FP
Sbjct: 205 ALQLGLLFP 213
>XP_005255403
          Length = 744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  TSLVFP 9
          TSLVFP
Sbjct: 86 TSLVFP 91
>XP_006716433
          Length = 3069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QTSLVFP 9
           QTS VFP
Sbjct: 495 QTSTVFP 501
>XP_005273633
          Length = 3069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QTSLVFP 9
           QTS VFP
Sbjct: 495 QTSTVFP 501
>XP_006716432
          Length = 3172

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QTSLVFP 9
           QTS VFP
Sbjct: 598 QTSTVFP 604
>XP_005273632
          Length = 3172

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QTSLVFP 9
           QTS VFP
Sbjct: 598 QTSTVFP 604
>XP_005246888
          Length = 22663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 20323 TSLVFP 20328
>XP_006712788
          Length = 24022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 21682 TSLVFP 21687
>XP_006712787
          Length = 33978

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 31638 TSLVFP 31643
>XP_006712786
          Length = 35484

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 33144 TSLVFP 33149
>NP_112561
          Length = 2789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QTSLVFP 9
           QTS VFP
Sbjct: 215 QTSTVFP 221
>NP_001254479
          Length = 35991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 33651 TSLVFP 33656
>NP_597681
          Length = 27118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4     TSLVFP 9
             TSLVFP
Sbjct: 24778 TSLVFP 24783
>NP_005752
          Length = 1568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ALQTSLVF 8
            ALQT LV+
Sbjct: 1094 ALQTKLVY 1101
>NP_001248385
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>NP_002339
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>NP_001028839
          Length = 193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>NP_001248386
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_006719249
          Length = 1555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ALQTSLVF 8
            ALQT LV+
Sbjct: 1081 ALQTKLVY 1088
>XP_006711388
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_006711387
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_006711386
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_006711385
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_006711384
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_006711383
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>XP_005245221
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQTSLVF 8
          LQTSL+F
Sbjct: 32 LQTSLLF 38
>NP_071405
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QTSLVFP 9
           QT+L+FP
Sbjct: 230 QTALMFP 236
>NP_001257354
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALQTSLV 7
           ALQTS+V
Sbjct: 670 ALQTSIV 676
>NP_003609
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALQTSLV 7
           ALQTS+V
Sbjct: 691 ALQTSIV 697
>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQTSLVFP 9
           ++TSL FP
Sbjct: 191 VKTSLTFP 198
>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQTSLVFP 9
           ++TSL FP
Sbjct: 162 VKTSLTFP 169
>XP_005245751
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  QTSLVF 8
          QTSLVF
Sbjct: 54 QTSLVF 59
>XP_005245750
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  QTSLVF 8
          QTSLVF
Sbjct: 54 QTSLVF 59
>XP_005277490
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LQTSLVFP 9
          L TS++FP
Sbjct: 41 LTTSMLFP 48
>XP_005277491
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LQTSLVFP 9
          L TS++FP
Sbjct: 41 LTTSMLFP 48
>XP_005277489
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LQTSLVFP 9
          L TS++FP
Sbjct: 41 LTTSMLFP 48
>NP_612440
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ALQTSLVF 8
           A QT+LVF
Sbjct: 295 ACQTALVF 302
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.134    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,492
Number of extensions: 396
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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