Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_982284                                                              17    4312
XP_005250571                                                           17    4312
XP_005250570                                                           17    4312
XP_005245099                                                           17    4312
XP_005245098                                                           17    4312
XP_005245097                                                           17    4312
NP_065930                                                              17    4312
NP_004371                                                              16    5631
NP_001073315                                                           16    5631
NP_065810                                                              16    5631
XP_005255182                                                           16    5631
XP_006720911                                                           16    5631
XP_005255181                                                           16    5631
XP_006720684                                                           16    5631
NP_057726                                                              16    7355
NP_036359                                                              16    7355
NP_714928                                                              16    7355
XP_006724931                                                           16    7355
XP_006724510                                                           16    7355
XP_005254495                                                           16    7355
XP_006713930                                                           16    7355
XP_006713929                                                           16    7355
XP_006713928                                                           16    7355
XP_006726390                                                           15    9605
XP_006726389                                                           15    9605
XP_006726388                                                           15    9605
XP_006726387                                                           15    9605
XP_006711142                                                           15    9605
XP_006711141                                                           15    9605
XP_006711140                                                           15    9605
XP_006710131                                                           15    9605
XP_006710130                                                           15    9605
XP_006710129                                                           15    9605
XP_006710128                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3424 ALQQRMEME 3432
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3440 ALQQRMEME 3448
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQRM ME
Sbjct: 3441 ALQQRMEME 3449
>NP_982284
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           +LQQ MLM+
Sbjct: 902 SLQQEMLMQ 910
>XP_005250571
          Length = 823

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           AL QR+L+E
Sbjct: 251 ALHQRLLLE 259
>XP_005250570
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           AL QR+L+E
Sbjct: 332 ALHQRLLLE 340
>XP_005245099
          Length = 1462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           +LQQ MLM+
Sbjct: 886 SLQQEMLMQ 894
>XP_005245098
          Length = 1473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           +LQQ MLM+
Sbjct: 897 SLQQEMLMQ 905
>XP_005245097
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           +LQQ MLM+
Sbjct: 913 SLQQEMLMQ 921
>NP_065930
          Length = 955

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQQRMLME 9
           AL QR+L+E
Sbjct: 383 ALHQRLLLE 391
>NP_004371
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQR+L +
Sbjct: 2290 ALQQRILQQ 2298
>NP_001073315
          Length = 2404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQR+L +
Sbjct: 2252 ALQQRILQQ 2260
>NP_065810
          Length = 4700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQ+ L+E
Sbjct: 1486 ALQQKYLLE 1494
>XP_005255182
          Length = 2303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQR+L +
Sbjct: 2151 ALQQRILQQ 2159
>XP_006720911
          Length = 2355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQR+L +
Sbjct: 2203 ALQQRILQQ 2211
>XP_005255181
          Length = 2427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQR+L +
Sbjct: 2275 ALQQRILQQ 2283
>XP_006720684
          Length = 4713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ALQQRMLME 9
            ALQQ+ L+E
Sbjct: 1499 ALQQKYLLE 1507
>NP_057726
          Length = 3674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALQQRML 7
           ALQQR+L
Sbjct: 413 ALQQRLL 419
>NP_036359
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 259 LQQRLLRE 266
>NP_714928
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 721 LQQRLLAE 728
>XP_006724931
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 120 LQQRLLRE 127
>XP_006724510
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 120 LQQRLLRE 127
>XP_005254495
          Length = 3694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALQQRML 7
           ALQQR+L
Sbjct: 433 ALQQRLL 439
>XP_006713930
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 721 LQQRLLAE 728
>XP_006713929
          Length = 930

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 721 LQQRLLAE 728
>XP_006713928
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQQRMLME 9
           LQQR+L E
Sbjct: 721 LQQRLLAE 728
>XP_006726390
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 650 LQQRML 655
>XP_006726389
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 768 LQQRML 773
>XP_006726388
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 786 LQQRML 791
>XP_006726387
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 834 LQQRML 839
>XP_006711142
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 768 LQQRML 773
>XP_006711141
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 786 LQQRML 791
>XP_006711140
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 834 LQQRML 839
>XP_006710131
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 650 LQQRML 655
>XP_006710130
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 768 LQQRML 773
>XP_006710129
          Length = 1489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 786 LQQRML 791
>XP_006710128
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LQQRML 7
           LQQRML
Sbjct: 834 LQQRML 839
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.130    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,600
Number of extensions: 744
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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