Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     299
NP_001075109                                                           20     299
NP_001013725                                                           16    5631
NP_001229268                                                           16    5631
NP_002618                                                              16    5631
XP_005254450                                                           16    5631
XP_005254449                                                           16    5631
XP_005252524                                                           16    5631
XP_005252523                                                           16    5631
XP_006717512                                                           16    5631
XP_005252522                                                           16    5631
NP_001274732                                                           16    7355
NP_115703                                                              16    7355
NP_932160                                                              16    7355
NP_001274733                                                           16    7355
NP_932161                                                              16    7355
NP_932163                                                              16    7355
NP_079173                                                              16    7355
NP_001259041                                                           16    7355
NP_001259040                                                           16    7355
NP_001259039                                                           16    7355
NP_001259038                                                           16    7355
NP_001259035                                                           16    7355
NP_001259042                                                           16    7355
NP_057736                                                              16    7355
XP_006718089                                                           16    7355
XP_006718088                                                           16    7355
XP_006718087                                                           16    7355
XP_006718086                                                           16    7355
XP_006718085                                                           16    7355
XP_006718084                                                           16    7355
XP_005245551                                                           16    7355
XP_006711616                                                           16    7355
XP_006711615                                                           16    7355
XP_006711612                                                           16    7355
XP_006711611                                                           16    7355
XP_005245548                                                           16    7355
XP_006711610                                                           16    7355
XP_006711609                                                           16    7355
XP_006711608                                                           16    7355
XP_006711607                                                           16    7355
XP_006711606                                                           16    7355
XP_006711605                                                           16    7355
>NP_008835
          Length = 4128

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ALQLRTYSI 9
            ALQLRTYS+
Sbjct: 3785 ALQLRTYSV 3793
>NP_001075109
          Length = 4097

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ALQLRTYSI 9
            ALQLRTYS+
Sbjct: 3785 ALQLRTYSV 3793
>NP_001013725
          Length = 1649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    ALQLRTYSI 9
            ALQ R YSI
Sbjct: 1190 ALQERNYSI 1198
>NP_001229268
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQLRTYSI 9
           A Q+RT+SI
Sbjct: 484 ATQMRTHSI 492
>NP_002618
          Length = 784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQLRTYSI 9
           A Q+RT+SI
Sbjct: 492 ATQMRTHSI 500
>XP_005254450
          Length = 1505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    ALQLRTYSI 9
            ALQ R YSI
Sbjct: 1190 ALQERNYSI 1198
>XP_005254449
          Length = 1626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    ALQLRTYSI 9
            ALQ R YSI
Sbjct: 1190 ALQERNYSI 1198
>XP_005252524
          Length = 746

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQLRTYSI 9
           A Q+RT+SI
Sbjct: 454 ATQMRTHSI 462
>XP_005252523
          Length = 784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQLRTYSI 9
           A Q+RT+SI
Sbjct: 492 ATQMRTHSI 500
>XP_006717512
          Length = 797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQLRTYSI 9
           A Q+RT+SI
Sbjct: 454 ATQMRTHSI 462
>XP_005252522
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALQLRTYSI 9
           A Q+RT+SI
Sbjct: 492 ATQMRTHSI 500
>NP_001274732
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_115703
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_932160
          Length = 361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_001274733
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_932161
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_932163
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_079173
          Length = 351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 223 LQLGTYSL 230
>NP_001259041
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQLRTYSI 9
          LQL TYS+
Sbjct: 83 LQLGTYSL 90
>NP_001259040
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQLRTYSI 9
          LQL TYS+
Sbjct: 83 LQLGTYSL 90
>NP_001259039
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQLRTYSI 9
          LQL TYS+
Sbjct: 83 LQLGTYSL 90
>NP_001259038
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQLRTYSI 9
          LQL TYS+
Sbjct: 83 LQLGTYSL 90
>NP_001259035
          Length = 283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 155 LQLGTYSL 162
>NP_001259042
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQLRTYSI 9
          LQL TYS+
Sbjct: 83 LQLGTYSL 90
>NP_057736
          Length = 848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LQLRTYSI 9
          L+LR+YS+
Sbjct: 26 LELRSYSL 33
>XP_006718089
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718088
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718087
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718086
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718085
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718084
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_005245551
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LQLRTYSI 9
          LQL TYS+
Sbjct: 83 LQLGTYSL 90
>XP_006711616
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 218 LQLGTYSL 225
>XP_006711615
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 218 LQLGTYSL 225
>XP_006711612
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 246 LQLGTYSL 253
>XP_006711611
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 305 LQLGTYSL 312
>XP_005245548
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 326 LQLGTYSL 333
>XP_006711610
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 329 LQLGTYSL 336
>XP_006711609
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 329 LQLGTYSL 336
>XP_006711608
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 354 LQLGTYSL 361
>XP_006711607
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 357 LQLGTYSL 364
>XP_006711606
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 378 LQLGTYSL 385
>XP_006711605
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQLRTYSI 9
           LQL TYS+
Sbjct: 423 LQLGTYSL 430
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.135    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 440,381
Number of extensions: 520
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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