Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_758955                                                              15    9605
NP_031363                                                              15    9605
NP_031361                                                              15    9605
NP_940933                                                              15    9605
XP_006722513                                                           15    9605
XP_006722512                                                           15    9605
XP_006722510                                                           15    9605
XP_005266750                                                           15    9605
XP_005266749                                                           15    9605
XP_005266748                                                           15    9605
XP_005266747                                                           15    9605
XP_006713504                                                           15    9605
XP_006713503                                                           15    9605
XP_005265688                                                           15    9605
XP_006713502                                                           15    9605
XP_006713501                                                           15    9605
XP_006713500                                                           15    9605
XP_005265687                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ALMVAITVS 9
            A+MVAITVS
Sbjct: 2862 AIMVAITVS 2870
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ALMVAITVS 9
            A+MVAITVS
Sbjct: 2657 AIMVAITVS 2665
>NP_758955
          Length = 177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LMVAITVS 9
           +MVA+TV+
Sbjct: 164 IMVAVTVN 171
>NP_031363
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
>NP_031361
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
>NP_940933
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LMVAITV 8
            LMVA+TV
Sbjct: 1056 LMVALTV 1062
>XP_006722513
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LMVAITV 8
           LMVA+TV
Sbjct: 696 LMVALTV 702
>XP_006722512
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LMVAITV 8
           LMVA+TV
Sbjct: 750 LMVALTV 756
>XP_006722510
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LMVAITV 8
           LMVA+TV
Sbjct: 963 LMVALTV 969
>XP_005266750
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LMVAITV 8
            LMVA+TV
Sbjct: 1015 LMVALTV 1021
>XP_005266749
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LMVAITV 8
            LMVA+TV
Sbjct: 1056 LMVALTV 1062
>XP_005266748
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LMVAITV 8
            LMVA+TV
Sbjct: 1056 LMVALTV 1062
>XP_005266747
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LMVAITV 8
            LMVA+TV
Sbjct: 1056 LMVALTV 1062
>XP_006713504
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LMVAITVS 9
           L VAIT+S
Sbjct: 370 LQVAITIS 377
>XP_006713503
          Length = 1438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
>XP_005265688
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LMVAITVS 9
           L VAIT+S
Sbjct: 772 LQVAITIS 779
>XP_006713502
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
>XP_006713501
          Length = 1727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
>XP_006713500
          Length = 1746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
>XP_005265687
          Length = 1758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LMVAITVS 9
            L VAIT+S
Sbjct: 1073 LQVAITIS 1080
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.128    0.284 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 165,471
Number of extensions: 90
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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