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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1482
NP_001265522                                                           17    2528
NP_005580                                                              17    2528
NP_689775                                                              16    5631
NP_112589                                                              16    5631
XP_006716359                                                           16    5631
XP_006716358                                                           16    5631
XP_006716357                                                           16    5631
XP_006711414                                                           16    5631
NP_038466                                                              16    7355
NP_444295                                                              16    7355
NP_064516                                                              16    7355
NP_001269461                                                           16    7355
NP_056154                                                              16    7355
NP_001269460                                                           16    7355
NP_852107                                                              16    7355
XP_006723822                                                           16    7355
XP_005245404                                                           16    7355
NP_001189368                                                           15    9605
NP_694574                                                              15    9605
NP_001278261                                                           15    9605
NP_001034553                                                           15    9605
NP_001159580                                                           15    9605
NP_057165                                                              15    9605
NP_001159582                                                           15    9605
NP_001159581                                                           15    9605
XP_005256319                                                           15    9605
XP_006721414                                                           15    9605
XP_005262923                                                           15    9605
XP_005262922                                                           15    9605
XP_005262921                                                           15    9605
XP_005262920                                                           15    9605
XP_005262919                                                           15    9605
XP_005262918                                                           15    9605
XP_003846678                                                           15    9605

>NP_004251
          Length = 1208

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ALLTLQQGK 9
           ALLTL QGK
Sbjct: 687 ALLTLLQGK 695



>NP_001265522
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLTLQQGK 9
           L+TL+QGK
Sbjct: 109 LITLEQGK 116



>NP_005580
          Length = 535

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLTLQQGK 9
           L+TL+QGK
Sbjct: 122 LITLEQGK 129



>NP_689775
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LTLQQG+
Sbjct: 731 LTLQQGQ 737



>NP_112589
          Length = 268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LTL+QGK
Sbjct: 213 LTLRQGK 219



>XP_006716359
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LTLQQG+
Sbjct: 736 LTLQQGQ 742



>XP_006716358
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LTLQQG+
Sbjct: 736 LTLQQGQ 742



>XP_006716357
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LTLQQG+
Sbjct: 736 LTLQQGQ 742



>XP_006711414
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ALLTLQQG 8
          ALLT QQG
Sbjct: 6  ALLTHQQG 13



>NP_038466
          Length = 589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ALLTLQQG 8
           ALL +QQG
Sbjct: 462 ALLQIQQG 469



>NP_444295
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ALLTLQQG 8
           ALL +QQG
Sbjct: 434 ALLQIQQG 441



>NP_064516
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ALLTLQQG 8
           ALL +QQG
Sbjct: 468 ALLQIQQG 475



>NP_001269461
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LTLQQG 8
           LTLQQG
Sbjct: 552 LTLQQG 557



>NP_056154
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LTLQQG 8
           LTLQQG
Sbjct: 552 LTLQQG 557



>NP_001269460
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LTLQQG 8
           LTLQQG
Sbjct: 552 LTLQQG 557



>NP_852107
          Length = 1102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LTLQQG 8
           LTLQQG
Sbjct: 552 LTLQQG 557



>XP_006723822
          Length = 1111

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LTLQQG 8
           LTLQQG
Sbjct: 561 LTLQQG 566



>XP_005245404
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ALLTLQQG 8
           ALL +QQG
Sbjct: 468 ALLQIQQG 475



>NP_001189368
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ALLTLQQGK 9
           ALLT+  GK
Sbjct: 388 ALLTVTSGK 396



>NP_694574
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTLQQGK 9
           LLTL QG+
Sbjct: 186 LLTLTQGE 193



>NP_001278261
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLTLQQG 8
           LLT+Q+G
Sbjct: 653 LLTMQEG 659



>NP_001034553
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LLTLQQG 8
            LLT+Q+G
Sbjct: 1135 LLTMQEG 1141



>NP_001159580
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LT+Q+GK
Sbjct: 937 LTVQEGK 943



>NP_057165
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LT+Q+GK
Sbjct: 920 LTVQEGK 926



>NP_001159582
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LT+Q+GK
Sbjct: 433 LTVQEGK 439



>NP_001159581
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LT+Q+GK
Sbjct: 538 LTVQEGK 544



>XP_005256319
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTLQQGK 9
           LLTL QG+
Sbjct: 186 LLTLTQGE 193



>XP_006721414
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLTLQQGK 9
           LLTL QG+
Sbjct: 100 LLTLTQGE 107



>XP_005262923
          Length = 1018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LTLQQGK 9
           LT+Q+GK
Sbjct: 779 LTVQEGK 785



>XP_005262922
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LTLQQGK 9
            LT+Q+GK
Sbjct: 1037 LTVQEGK 1043



>XP_005262921
          Length = 1309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LTLQQGK 9
            LT+Q+GK
Sbjct: 1070 LTVQEGK 1076



>XP_005262920
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LTLQQGK 9
            LT+Q+GK
Sbjct: 1161 LTVQEGK 1167



>XP_005262919
          Length = 1383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LTLQQGK 9
            LT+Q+GK
Sbjct: 1144 LTVQEGK 1150



>XP_005262918
          Length = 1400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LTLQQGK 9
            LT+Q+GK
Sbjct: 1161 LTVQEGK 1167



>XP_003846678
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ALLTLQQGK 9
           ALLT Q G+
Sbjct: 96  ALLTSQMGR 104




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ALLTLQQGK 9
           ALLT Q G+
Sbjct: 213 ALLTSQMGR 221



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.131    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 497,707
Number of extensions: 742
Number of successful extensions: 36
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)