Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     869
NP_001129525                                                           17    3301
XP_006713560                                                           17    3301
XP_006713559                                                           17    3301
XP_006713558                                                           17    3301
NP_473371                                                              17    4312
NP_055872                                                              16    5631
NP_056392                                                              16    5631
NP_001138997                                                           16    5631
NP_001138995                                                           16    5631
NP_001138994                                                           16    5631
NP_001138993                                                           16    5631
NP_001138992                                                           16    5631
NP_909119                                                              16    5631
NP_057537                                                              16    5631
XP_006719852                                                           16    5631
XP_005266357                                                           16    5631
XP_006719851                                                           16    5631
XP_006719850                                                           16    5631
XP_006719849                                                           16    5631
XP_006719848                                                           16    5631
XP_005266356                                                           16    5631
XP_006719847                                                           16    5631
XP_006719846                                                           16    5631
XP_006719845                                                           16    5631
XP_006719844                                                           16    5631
XP_006719843                                                           16    5631
XP_006719842                                                           16    5631
XP_006714532                                                           16    5631
XP_005265280                                                           16    5631
XP_006713268                                                           16    5631
NP_001129334                                                           16    7355
NP_612424                                                              16    7355
NP_001229379                                                           16    7355
NP_065070                                                              16    7355
NP_036447                                                              16    7355
NP_001275631                                                           16    7355
NP_699169                                                              16    7355
NP_001116362                                                           16    7355
NP_001271225                                                           16    7355
NP_001138874                                                           16    7355
XP_006724185                                                           16    7355
NP_000535                                                              15    9605
NP_061313                                                              15    9605
NP_000531                                                              15    9605
NP_001036188                                                           15    9605
NP_001230925                                                           15    9605
NP_001276972                                                           15    9605
NP_001027                                                              15    9605
NP_071934                                                              15    9605
NP_037477                                                              15    9605
NP_001265623                                                           15    9605
NP_001026884                                                           15    9605
NP_001265624                                                           15    9605
XP_006723382                                                           15    9605
XP_006723381                                                           15    9605
XP_006723380                                                           15    9605
XP_005268062                                                           15    9605
XP_005268061                                                           15    9605
>NP_004251
          Length = 1208

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL+LLQGK
Sbjct: 687 ALLTLLQGK 695
>NP_001129525
          Length = 373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ALLSLLQG 8
           ALL+LLQG
Sbjct: 236 ALLNLLQG 243
>XP_006713560
          Length = 373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ALLSLLQG 8
           ALL+LLQG
Sbjct: 236 ALLNLLQG 243
>XP_006713559
          Length = 373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ALLSLLQG 8
           ALL+LLQG
Sbjct: 236 ALLNLLQG 243
>XP_006713558
          Length = 373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   ALLSLLQG 8
           ALL+LLQG
Sbjct: 236 ALLNLLQG 243
>NP_473371
          Length = 330

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSLLQGK 9
           LLS+L+GK
Sbjct: 159 LLSILEGK 166
>NP_055872
          Length = 4678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>NP_056392
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>NP_001138997
          Length = 983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 351 LLSLLQAK 358
>NP_001138995
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 340 LLSLLQAK 347
>NP_001138994
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 319 LLSLLQAK 326
>NP_001138993
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>NP_001138992
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>NP_909119
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSLLQGK 9
           LLSL++GK
Sbjct: 350 LLSLVEGK 357
>NP_057537
          Length = 722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSLLQGK 9
           LLSL++GK
Sbjct: 357 LLSLVEGK 364
>XP_006719852
          Length = 4752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_005266357
          Length = 4600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719851
          Length = 4689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719850
          Length = 4697

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719849
          Length = 4703

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719848
          Length = 4737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_005266356
          Length = 4755

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719847
          Length = 4761

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719846
          Length = 4763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719845
          Length = 4772

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719844
          Length = 4789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719843
          Length = 4794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006719842
          Length = 4797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ALLSLLQGK 9
           ALL++LQG+
Sbjct: 228 ALLNVLQGQ 236
>XP_006714532
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSLLQGK 9
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>XP_005265280
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSLLQGK 9
           LLSL++GK
Sbjct: 279 LLSLVEGK 286
>XP_006713268
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSLLQGK 9
           LLSL++GK
Sbjct: 357 LLSLVEGK 364
>NP_001129334
          Length = 489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLSLLQGK 9
           ALL L+QG+
Sbjct: 442 ALLRLIQGE 450
>NP_612424
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLSLLQGK 9
           ALL L+QG+
Sbjct: 484 ALLRLIQGE 492
>NP_001229379
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLSLLQGK 9
           ALL L+QG+
Sbjct: 430 ALLRLIQGE 438
>NP_065070
          Length = 1429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  ALLSLLQGK 9
          A  SLLQGK
Sbjct: 13 AQTSLLQGK 21
>NP_036447
          Length = 250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALLSLL G
Sbjct: 8  ALLSLLAG 15
>NP_001275631
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ALLSLLQG 8
           ALLSLL G
Sbjct: 279 ALLSLLAG 286
>NP_699169
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ALLSLLQG 8
           ALLSLL G
Sbjct: 241 ALLSLLAG 248
>NP_001116362
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ALLSLLQG 8
           ALLSLL G
Sbjct: 273 ALLSLLAG 280
>NP_001271225
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLSLLQGK 9
           ALL L+QG+
Sbjct: 280 ALLRLIQGE 288
>NP_001138874
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSLLQGK 9
           LSLL+GK
Sbjct: 745 LSLLEGK 751
>XP_006724185
          Length = 489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLSLLQGK 9
           ALL L+QG+
Sbjct: 442 ALLRLIQGE 450
>NP_000535
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALL LLQG
Sbjct: 18 ALLWLLQG 25
>NP_061313
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALL LLQG
Sbjct: 18 ALLWLLQG 25
>NP_000531
          Length = 5038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 4026 LLSLLEG 4032
>NP_001036188
          Length = 5033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 4021 LLSLLEG 4027
>NP_001230925
          Length = 4865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 3873 LLSLLEG 3879
>NP_001276972
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALL LLQG
Sbjct: 18 ALLWLLQG 25
>NP_001027
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 3878 LLSLLEG 3884
>NP_071934
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLSLLQG 8
           LLS+LQG
Sbjct: 291 LLSVLQG 297
>NP_037477
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALL +LQG
Sbjct: 67 ALLQVLQG 74
>NP_001265623
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALL +LQG
Sbjct: 67 ALLQVLQG 74
>NP_001026884
          Length = 1240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLSLLQG 8
           LLS+LQG
Sbjct: 291 LLSVLQG 297
>NP_001265624
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALLSLLQG 8
          ALL +LQG
Sbjct: 58 ALLQVLQG 65
>XP_006723382
          Length = 5027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 4015 LLSLLEG 4021
>XP_006723381
          Length = 5031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 4019 LLSLLEG 4025
>XP_006723380
          Length = 5032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LLSLLQG 8
            LLSLL+G
Sbjct: 4020 LLSLLEG 4026
>XP_005268062
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLSLLQG 8
           LLS+LQG
Sbjct: 323 LLSVLQG 329
>XP_005268061
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLSLLQG 8
           LLS+LQG
Sbjct: 323 LLSVLQG 329
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.138    0.338 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,455
Number of extensions: 786
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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